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2. CHEK2 germline variants identified in familial nonmedullary thyroid cancer lead to impaired protein structure and function. Pires C; Marques IJ; Valério M; Saramago A; Santo PE; Santos S; Silva M; Moura MM; Matos J; Pereira T; Cabrera R; Lousa D; Leite V; Bandeiras TM; Vicente JB; Cavaco BM J Biol Chem; 2024 Mar; 300(3):105767. PubMed ID: 38367672 [TBL] [Abstract][Full Text] [Related]
3. Germline CHEK2 Gene Mutations in Hereditary Breast Cancer Predisposition - Mutation Types and their Biological and Clinical Relevance. Kleiblová P; Stolařová L; Křížová K; Lhota F; Hojný J; Zemánková P; Havránek O; Vočka M; Černá M; Lhotová K; Borecká M; Janatová M; Soukupová J; Ševčík J; Zimovjanová M; Kotlas J; Panczak A; Veselá K; Červenková J; Schneiderová M; Burócziová M; Burdová K; Stránecký V; Foretová L; Macháčková E; Tavandzis S; Kmoch S; Macůrek L; Kleibl Z Klin Onkol; 2019; 32(Supplementum2):36-50. PubMed ID: 31409080 [TBL] [Abstract][Full Text] [Related]
4. Functional Analysis Identifies Damaging CHEK2 Missense Variants Associated with Increased Cancer Risk. Boonen RACM; Wiegant WW; Celosse N; Vroling B; Heijl S; Kote-Jarai Z; Mijuskovic M; Cristea S; Solleveld-Westerink N; van Wezel T; Beerenwinkel N; Eeles R; Devilee P; Vreeswijk MPG; Marra G; van Attikum H Cancer Res; 2022 Feb; 82(4):615-631. PubMed ID: 34903604 [TBL] [Abstract][Full Text] [Related]
5. The CHK2 kinase is recurrently mutated and functionally impaired in the germline of pediatric cancer patients. Wagener R; Walter C; Auer F; Alzoubi D; Hauer J; Fischer U; Varghese J; Dugas M; Borkhardt A; Brozou T Int J Cancer; 2023 Apr; 152(7):1388-1398. PubMed ID: 36468172 [TBL] [Abstract][Full Text] [Related]
6. Frequency of pathogenic germline mutation in CHEK2, PALB2, MRE11, and RAD50 in patients at high risk for hereditary breast cancer. Kim H; Cho DY; Choi DH; Oh M; Shin I; Park W; Huh SJ; Nam SJ; Lee JE; Kim SW Breast Cancer Res Treat; 2017 Jan; 161(1):95-102. PubMed ID: 27783279 [TBL] [Abstract][Full Text] [Related]
7. Germline mutations in a DNA repair pathway are associated with familial colorectal cancer. Xu P; Sun D; Gao Y; Jiang Y; Zhong M; Zhao G; Chen J; Wang Z; Liu Q; Hong J; Chen H; Chen YX; Fang JY JCI Insight; 2021 Sep; 6(18):. PubMed ID: 34549727 [TBL] [Abstract][Full Text] [Related]
8. Germline CHEK2 and ATM Variants in Myeloid and Other Hematopoietic Malignancies. Stubbins RJ; Korotev S; Godley LA Curr Hematol Malig Rep; 2022 Aug; 17(4):94-104. PubMed ID: 35674998 [TBL] [Abstract][Full Text] [Related]
9. CHEK2 1100DELC germline mutation: a frequency study in hereditary breast and colon cancer Brazilian families. Abud J; Koehler-Santos P; Ashton-Prolla P; Prolla JC; Arq Gastroenterol; 2012 Dec; 49(4):273-8. PubMed ID: 23329222 [TBL] [Abstract][Full Text] [Related]
10. Identification of deleterious germline CHEK2 mutations and their association with breast and ovarian cancer. Kleiblova P; Stolarova L; Krizova K; Lhota F; Hojny J; Zemankova P; Havranek O; Vocka M; Cerna M; Lhotova K; Borecka M; Janatova M; Soukupova J; Sevcik J; Zimovjanova M; Kotlas J; Panczak A; Vesela K; Cervenkova J; Schneiderova M; Burocziova M; Burdova K; Stranecky V; Foretova L; Machackova E; Tavandzis S; Kmoch S; Macurek L; Kleibl Z Int J Cancer; 2019 Oct; 145(7):1782-1797. PubMed ID: 31050813 [TBL] [Abstract][Full Text] [Related]
11. Immunohistochemical findings and clinicopathological features of breast cancers with pathogenic germline mutations in Non-BRCA genes. Singh K; Scalia J; Legare R; Quddus MR; Sung CJ Hum Pathol; 2024 Apr; 146():49-56. PubMed ID: 38608781 [TBL] [Abstract][Full Text] [Related]
12. Genomic profiling of pelvic genital type leiomyosarcoma in a woman with a germline Thibodeau ML; Reisle C; Zhao E; Martin LA; Alwelaie Y; Mungall KL; Ch'ng C; Thomas R; Ng T; Yip S; J Lim H; Sun S; Young SS; Karsan A; Zhao Y; Mungall AJ; Moore RA; J Renouf D; Gelmon K; Ma YP; Hayes M; Laskin J; Marra MA; Schrader KA; Jones SJM Cold Spring Harb Mol Case Stud; 2017 Sep; 3(5):. PubMed ID: 28514723 [TBL] [Abstract][Full Text] [Related]
13. Profiling of the genetic features of patients with breast, ovarian, colorectal and extracolonic cancers: Association to CHEK2 and PALB2 germline mutations. Infante M; Arranz-Ledo M; Lastra E; Olaverri A; Ferreira R; Orozco M; Hernández L; Martínez N; Durán M Clin Chim Acta; 2024 Jan; 552():117695. PubMed ID: 38061684 [TBL] [Abstract][Full Text] [Related]
14. A Germline Zhao Y; Yu T; Chen L; Xie D; Wang F; Fu L; Cheng C; Li Y; Zhu X; Miao G Thyroid; 2020 Jun; 30(6):924-930. PubMed ID: 32041497 [TBL] [Abstract][Full Text] [Related]
15. Association of Germline CHEK2 Gene Variants with Risk and Prognosis of Non-Hodgkin Lymphoma. Havranek O; Kleiblova P; Hojny J; Lhota F; Soucek P; Trneny M; Kleibl Z PLoS One; 2015; 10(10):e0140819. PubMed ID: 26506619 [TBL] [Abstract][Full Text] [Related]
16. ENIGMA CHEK2gether Project: A Comprehensive Study Identifies Functionally Impaired CHEK2 Germline Missense Variants Associated with Increased Breast Cancer Risk. Stolarova L; Kleiblova P; Zemankova P; Stastna B; Janatova M; Soukupova J; Achatz MI; Ambrosone C; Apostolou P; Arun BK; Auer P; Barnard M; Bertelsen B; ; Blok MJ; Boddicker N; Brunet J; Burnside ES; Calvello M; Campbell I; Chan SH; Chen F; Chiang JB; Coppa A; Cortesi L; Crujeiras-González A; ; De Leeneer K; De Putter R; DePersia A; Devereux L; Domchek S; Efremidis A; Engel C; Ernst C; Evans DGR; Feliubadaló L; Fostira F; Fuentes-Ríos O; Gómez-García EB; González S; Haiman C; Hansen TVO; Hauke J; Hodge J; Hu C; Huang H; Ishak NDB; Iwasaki Y; Konstantopoulou I; Kraft P; Lacey J; Lázaro C; Li N; Lim WK; Lindstrom S; Lori A; Martinez E; Martins A; Matsuda K; Matullo G; McInerny S; Michailidou K; Montagna M; Monteiro ANA; Mori L; Nathanson K; Neuhausen SL; Nevanlinna H; Olson JE; Palmer J; Pasini B; Patel A; Piane M; Poppe B; Radice P; Renieri A; Resta N; Richardson ME; Rosseel T; Ruddy KJ; Santamariña M; Dos Santos ES; Teras L; Toland AE; Trentham-Dietz A; Vachon CM; Volk AE; Weber-Lassalle N; Weitzel JN; Wiesmuller L; Winham S; Yadav S; Yannoukakos D; Yao S; Zampiga V; Zethoven M; Zhang ZW; Zima T; Spurdle AB; Vega A; Rossing M; Del Valle J; De Nicolo A; Hahnen E; Claes KBM; Ngeow J; Momozawa Y; James PA; Couch FJ; Macurek L; Kleibl Z Clin Cancer Res; 2023 Aug; 29(16):3037-3050. PubMed ID: 37449874 [TBL] [Abstract][Full Text] [Related]
17. Association of Inherited Pathogenic Variants in Checkpoint Kinase 2 (CHEK2) With Susceptibility to Testicular Germ Cell Tumors. AlDubayan SH; Pyle LC; Gamulin M; Kulis T; Moore ND; Taylor-Weiner A; Hamid AA; Reardon B; Wubbenhorst B; Godse R; Vaughn DJ; Jacobs LA; Meien S; Grgic M; Kastelan Z; Markt SC; Damrauer SM; Rader DJ; Kember RL; Loud JT; Kanetsky PA; Greene MH; Sweeney CJ; Kubisch C; Nathanson KL; Van Allen EM; Stewart DR; Lessel D; JAMA Oncol; 2019 Apr; 5(4):514-522. PubMed ID: 30676620 [TBL] [Abstract][Full Text] [Related]
18. The heterogeneous cancer phenotype of individuals with biallelic germline pathogenic variants in CHEK2. Hinić S; Cybulski C; Van der Post RS; Vos JR; Schuurs-Hoeijmakers J; Brugnoletti F; Koene S; Vreede L; van Zelst-Stams WAG; Kets CM; Haadsma M; Spruijt L; Wevers MR; Evans DG; Wimmer K; Schnaiter S; Volk AE; Möllring A; de Putter R; Soikkonen L; Kahre T; Tooming M; de Jong MM; Vaz F; Mensenkamp AR; Genuardi M; Lubinski J; Ligtenberg M; Hoogerbrugge N; de Voer RM Genet Med; 2024 May; 26(5):101101. PubMed ID: 38362852 [TBL] [Abstract][Full Text] [Related]
19. First evidence of a large CHEK2 duplication involved in cancer predisposition in an Italian family with hereditary breast cancer. Tedaldi G; Danesi R; Zampiga V; Tebaldi M; Bedei L; Zoli W; Amadori D; Falcini F; Calistri D BMC Cancer; 2014 Jul; 14():478. PubMed ID: 24986639 [TBL] [Abstract][Full Text] [Related]
20. Roles of Chk2/CHEK2 in guarding against environmentally induced DNA damage and replication-stress. Mustofa MK; Tanoue Y; Tateishi C; Vaziri C; Tateishi S Environ Mol Mutagen; 2020 Aug; 61(7):730-735. PubMed ID: 32578892 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]