417 related articles for article (PubMed ID: 33326752)
21. Glycine homeostasis requires reverse SHMT flux.
McBride MJ; Hunter CJ; Zhang Z; TeSlaa T; Xu X; Ducker GS; Rabinowitz JD
Cell Metab; 2024 Jan; 36(1):103-115.e4. PubMed ID: 38171330
[TBL] [Abstract][Full Text] [Related]
22. Is mutated serine hydroxymethyltransferase (SHMT) involved in the etiology of neural tube defects?
Heil SG; Van der Put NM; Waas ET; den Heijer M; Trijbels FJ; Blom HJ
Mol Genet Metab; 2001 Jun; 73(2):164-72. PubMed ID: 11386852
[TBL] [Abstract][Full Text] [Related]
23. Serine hydroxymethyltransferase 1 and 2: gene sequence variation and functional genomic characterization.
Hebbring SJ; Chai Y; Ji Y; Abo RP; Jenkins GD; Fridley B; Zhang J; Eckloff BW; Wieben ED; Weinshilboum RM
J Neurochem; 2012 Mar; 120(6):881-90. PubMed ID: 22220685
[TBL] [Abstract][Full Text] [Related]
24. Human Cytosolic and Mitochondrial Serine Hydroxymethyltransferase Isoforms in Comparison: Full Kinetic Characterization and Substrate Inhibition Properties.
Tramonti A; Nardella C; di Salvo ML; Barile A; Cutruzzolà F; Contestabile R
Biochemistry; 2018 Dec; 57(51):6984-6996. PubMed ID: 30500180
[TBL] [Abstract][Full Text] [Related]
25. Disruption of shmt1 impairs hippocampal neurogenesis and mnemonic function in mice.
Abarinov EV; Beaudin AE; Field MS; Perry CA; Allen RH; Stabler SP; Stover PJ
J Nutr; 2013 Jul; 143(7):1028-35. PubMed ID: 23700346
[TBL] [Abstract][Full Text] [Related]
26. Differential inhibitory effect of a pyrazolopyran compound on human serine hydroxymethyltransferase-amino acid complexes.
Tramonti A; Paiardini A; Paone A; Bouzidi A; Giardina G; Guiducci G; Magnifico MC; Rinaldo S; McDermott L; Menendez JA; Contestabile R; Cutruzzolà F
Arch Biochem Biophys; 2018 Sep; 653():71-79. PubMed ID: 29991441
[TBL] [Abstract][Full Text] [Related]
27. Cytoplasmic serine hydroxymethyltransferase mediates competition between folate-dependent deoxyribonucleotide and S-adenosylmethionine biosyntheses.
Herbig K; Chiang EP; Lee LR; Hills J; Shane B; Stover PJ
J Biol Chem; 2002 Oct; 277(41):38381-9. PubMed ID: 12161434
[TBL] [Abstract][Full Text] [Related]
28. Quantitative flux analysis reveals folate-dependent NADPH production.
Fan J; Ye J; Kamphorst JJ; Shlomi T; Thompson CB; Rabinowitz JD
Nature; 2014 Jun; 510(7504):298-302. PubMed ID: 24805240
[TBL] [Abstract][Full Text] [Related]
29. Evidence for intracellular partitioning of serine and glycine metabolism in Chinese hamster ovary cells.
Narkewicz MR; Sauls SD; Tjoa SS; Teng C; Fennessey PV
Biochem J; 1996 Feb; 313 ( Pt 3)(Pt 3):991-6. PubMed ID: 8611185
[TBL] [Abstract][Full Text] [Related]
30. A pyrazolopyran derivative preferentially inhibits the activity of human cytosolic serine hydroxymethyltransferase and induces cell death in lung cancer cells.
Marani M; Paone A; Fiascarelli A; Macone A; Gargano M; Rinaldo S; Giardina G; Pontecorvi V; Koes D; McDermott L; Yang T; Paiardini A; Contestabile R; Cutruzzolà F
Oncotarget; 2016 Jan; 7(4):4570-83. PubMed ID: 26717037
[TBL] [Abstract][Full Text] [Related]
31. Nuclear respiratory factor 1 (NRF-1) upregulates the expression and function of reduced folate carrier (RFC) at the blood-brain barrier.
Alam C; Hoque MT; Sangha V; Bendayan R
FASEB J; 2020 Aug; 34(8):10516-10530. PubMed ID: 32543769
[TBL] [Abstract][Full Text] [Related]
32. Evidence for small ubiquitin-like modifier-dependent nuclear import of the thymidylate biosynthesis pathway.
Woeller CF; Anderson DD; Szebenyi DM; Stover PJ
J Biol Chem; 2007 Jun; 282(24):17623-31. PubMed ID: 17446168
[TBL] [Abstract][Full Text] [Related]
33. Depleted folate pool and dysfunctional mitochondria associated with defective mitochondrial folate proteins sensitize Chinese ovary cell mutants to tert-butylhydroperoxide-induced oxidative stress and apoptosis.
Ye YL; Chan YT; Liu HC; Lu HT; Huang RF
J Nutr Biochem; 2010 Sep; 21(9):793-800. PubMed ID: 19716280
[TBL] [Abstract][Full Text] [Related]
34. Differential 3-bromopyruvate inhibition of cytosolic and mitochondrial human serine hydroxymethyltransferase isoforms, key enzymes in cancer metabolic reprogramming.
Paiardini A; Tramonti A; Schirch D; Guiducci G; di Salvo ML; Fiascarelli A; Giorgi A; Maras B; Cutruzzolà F; Contestabile R
Biochim Biophys Acta; 2016 Nov; 1864(11):1506-17. PubMed ID: 27530298
[TBL] [Abstract][Full Text] [Related]
35. Human SHMT inhibitors reveal defective glycine import as a targetable metabolic vulnerability of diffuse large B-cell lymphoma.
Ducker GS; Ghergurovich JM; Mainolfi N; Suri V; Jeong SK; Hsin-Jung Li S; Friedman A; Manfredi MG; Gitai Z; Kim H; Rabinowitz JD
Proc Natl Acad Sci U S A; 2017 Oct; 114(43):11404-11409. PubMed ID: 29073064
[TBL] [Abstract][Full Text] [Related]
36. The catalytic activity of serine hydroxymethyltransferase is essential for de novo nuclear dTMP synthesis in lung cancer cells.
Giardina G; Paone A; Tramonti A; Lucchi R; Marani M; Magnifico MC; Bouzidi A; Pontecorvi V; Guiducci G; Zamparelli C; Rinaldo S; Paiardini A; Contestabile R; Cutruzzolà F
FEBS J; 2018 Sep; 285(17):3238-3253. PubMed ID: 30035852
[TBL] [Abstract][Full Text] [Related]
37. Reduced folate carrier independent internalization of PEGylated pemetrexed: a potential nanomedicinal approach for breast cancer therapy.
Vandana M; Sahoo SK
Mol Pharm; 2012 Oct; 9(10):2828-43. PubMed ID: 22894559
[TBL] [Abstract][Full Text] [Related]
38. Glycine decarboxylase maintains mitochondrial protein lipoylation to support tumor growth.
Mukha D; Fokra M; Feldman A; Sarvin B; Sarvin N; Nevo-Dinur K; Besser E; Hallo E; Aizenshtein E; Schug ZT; Shlomi T
Cell Metab; 2022 May; 34(5):775-782.e9. PubMed ID: 35508111
[TBL] [Abstract][Full Text] [Related]
39. Nucleotide biosynthesis arrest by silencing SHMT1 function via vitamin B6-coupled vector and effects on tumor growth inhibition.
Pandey S; Garg P; Lee S; Choung HW; Choung YH; Choung PH; Chung JH
Biomaterials; 2014 Nov; 35(34):9332-42. PubMed ID: 25132602
[TBL] [Abstract][Full Text] [Related]
40. Deletion of the neural tube defect-associated gene
Bryant JD; Sweeney SR; Sentandreu E; Shin M; Ipas H; Xhemalce B; Momb J; Tiziani S; Appling DR
J Biol Chem; 2018 Apr; 293(16):5821-5833. PubMed ID: 29483189
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]