BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

199 related articles for article (PubMed ID: 33340543)

  • 1. Force-dependent stimulation of RNA unwinding by SARS-CoV-2 nsp13 helicase.
    Mickolajczyk KJ; Shelton PMM; Grasso M; Cao X; Warrington SE; Aher A; Liu S; Kapoor TM
    Biophys J; 2021 Mar; 120(6):1020-1030. PubMed ID: 33340543
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Force-dependent stimulation of RNA unwinding by SARS-CoV-2 nsp13 helicase.
    Mickolajczyk KJ; Shelton PMM; Grasso M; Cao X; Warrington SR; Aher A; Liu S; Kapoor TM
    bioRxiv; 2020 Jul; ():. PubMed ID: 32766580
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A high ATP concentration enhances the cooperative translocation of the SARS coronavirus helicase nsP13 in the unwinding of duplex RNA.
    Jang KJ; Jeong S; Kang DY; Sp N; Yang YM; Kim DE
    Sci Rep; 2020 Mar; 10(1):4481. PubMed ID: 32161317
    [TBL] [Abstract][Full Text] [Related]  

  • 4. SARS-Coronavirus-2 Nsp13 Possesses NTPase and RNA Helicase Activities That Can Be Inhibited by Bismuth Salts.
    Shu T; Huang M; Wu D; Ren Y; Zhang X; Han Y; Mu J; Wang R; Qiu Y; Zhang DY; Zhou X
    Virol Sin; 2020 Jun; 35(3):321-329. PubMed ID: 32500504
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The stalk domain of SARS-CoV-2 NSP13 is essential for its helicase activity.
    Yue K; Yao B; Shi Y; Yang Y; Qian Z; Ci Y; Shi L
    Biochem Biophys Res Commun; 2022 Apr; 601():129-136. PubMed ID: 35245742
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Architecture of a SARS-CoV-2 mini replication and transcription complex.
    Yan L; Zhang Y; Ge J; Zheng L; Gao Y; Wang T; Jia Z; Wang H; Huang Y; Li M; Wang Q; Rao Z; Lou Z
    Nat Commun; 2020 Nov; 11(1):5874. PubMed ID: 33208736
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Activity and inhibition of the SARS-CoV-2 Omicron nsp13 R392C variant using RNA duplex unwinding assays.
    Inniss NL; Rzhetskaya M; Ling-Hu T; Lorenzo-Redondo R; Bachta KE; Satchell KJF; Hultquist JF
    SLAS Discov; 2024 Apr; 29(3):100145. PubMed ID: 38301954
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Biochemical analysis of SARS-CoV-2 Nsp13 helicase implicated in COVID-19 and factors that regulate its catalytic functions.
    Sommers JA; Loftus LN; Jones MP; Lee RA; Haren CE; Dumm AJ; Brosh RM
    J Biol Chem; 2023 Mar; 299(3):102980. PubMed ID: 36739951
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Structural Basis for Helicase-Polymerase Coupling in the SARS-CoV-2 Replication-Transcription Complex.
    Chen J; Malone B; Llewellyn E; Grasso M; Shelton PMM; Olinares PDB; Maruthi K; Eng ET; Vatandaslar H; Chait BT; Kapoor TM; Darst SA; Campbell EA
    Cell; 2020 Sep; 182(6):1560-1573.e13. PubMed ID: 32783916
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The PKA-CREB1 axis regulates coronavirus proliferation by viral helicase nsp13 association.
    Zheng T; Shen B; Bai Y; Li E; Zhang X; Hu Y; Gao T; Dong Q; Zhu L; Jin R; Shi H; Liu H; Gao Y; Liu X; Cao C
    J Virol; 2024 Apr; 98(4):e0156523. PubMed ID: 38445884
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Kinetic Characterization of SARS-CoV-2 nsp13 ATPase Activity and Discovery of Small-Molecule Inhibitors.
    Yazdi AK; Pakarian P; Perveen S; Hajian T; Santhakumar V; Bolotokova A; Li F; Vedadi M
    ACS Infect Dis; 2022 Aug; 8(8):1533-1542. PubMed ID: 35822715
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Structure, mechanism and crystallographic fragment screening of the SARS-CoV-2 NSP13 helicase.
    Newman JA; Douangamath A; Yadzani S; Yosaatmadja Y; Aimon A; Brandão-Neto J; Dunnett L; Gorrie-Stone T; Skyner R; Fearon D; Schapira M; von Delft F; Gileadi O
    Nat Commun; 2021 Aug; 12(1):4848. PubMed ID: 34381037
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Mapping major SARS-CoV-2 drug targets and assessment of druggability using computational fragment screening: Identification of an allosteric small-molecule binding site on the Nsp13 helicase.
    Freidel MR; Armen RS
    PLoS One; 2021; 16(2):e0246181. PubMed ID: 33596235
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Identifying SARS-CoV-2 antiviral compounds by screening for small molecule inhibitors of nsp13 helicase.
    Zeng J; Weissmann F; Bertolin AP; Posse V; Canal B; Ulferts R; Wu M; Harvey R; Hussain S; Milligan JC; Roustan C; Borg A; McCoy L; Drury LS; Kjaer S; McCauley J; Howell M; Beale R; Diffley JFX
    Biochem J; 2021 Jul; 478(13):2405-2423. PubMed ID: 34198322
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Unwinding mechanism of SARS-CoV helicase (nsp13) in the presence of Ca
    Yu J; Im H; Lee G
    Biochem Biophys Res Commun; 2023 Aug; 668():35-41. PubMed ID: 37235917
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The Coronavirus helicase in replication.
    Grimes SL; Denison MR
    Virus Res; 2024 Aug; 346():199401. PubMed ID: 38796132
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Single-base pair unwinding and asynchronous RNA release by the hepatitis C virus NS3 helicase.
    Cheng W; Arunajadai SG; Moffitt JR; Tinoco I; Bustamante C
    Science; 2011 Sep; 333(6050):1746-9. PubMed ID: 21940894
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Multiple enzymatic activities associated with severe acute respiratory syndrome coronavirus helicase.
    Ivanov KA; Thiel V; Dobbe JC; van der Meer Y; Snijder EJ; Ziebuhr J
    J Virol; 2004 Jun; 78(11):5619-32. PubMed ID: 15140959
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Deducing the Crystal Structure of MERS-CoV Helicase.
    Cui S; Hao W
    Methods Mol Biol; 2020; 2099():69-85. PubMed ID: 31883088
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A mutation in the coronavirus nsp13-helicase impairs enzymatic activity and confers partial remdesivir resistance.
    Grimes SL; Choi YJ; Banerjee A; Small G; Anderson-Daniels J; Gribble J; Pruijssers AJ; Agostini ML; Abu-Shmais A; Lu X; Darst SA; Campbell E; Denison MR
    mBio; 2023 Aug; 14(4):e0106023. PubMed ID: 37338298
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.