BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

114 related articles for article (PubMed ID: 33347281)

  • 1. Synthesis, Pharmacological, and Biological Evaluation of 2-Furoyl-Based MIF-1 Peptidomimetics and the Development of a General-Purpose Model for Allosteric Modulators (ALLOPTML).
    Sampaio-Dias IE; Rodríguez-Borges JE; Yáñez-Pérez V; Arrasate S; Llorente J; Brea JM; Bediaga H; Viña D; Loza MI; Caamaño O; García-Mera X; González-Díaz H
    ACS Chem Neurosci; 2021 Jan; 12(1):203-215. PubMed ID: 33347281
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthesis, Pharmacological, and Biological Evaluation of MIF-1 Picolinoyl Peptidomimetics as Positive Allosteric Modulators of D
    Sampaio-Dias IE; Silva-Reis SC; García-Mera X; Brea J; Loza MI; Alves CS; Algarra M; Rodríguez-Borges JE
    ACS Chem Neurosci; 2019 Aug; 10(8):3690-3702. PubMed ID: 31347842
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Perturbation Theory/Machine Learning Model of ChEMBL Data for Dopamine Targets: Docking, Synthesis, and Assay of New l-Prolyl-l-leucyl-glycinamide Peptidomimetics.
    Ferreira da Costa J; Silva D; Caamaño O; Brea JM; Loza MI; Munteanu CR; Pazos A; García-Mera X; González-Díaz H
    ACS Chem Neurosci; 2018 Nov; 9(11):2572-2587. PubMed ID: 29791132
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Discovery of New Potent Positive Allosteric Modulators of Dopamine D
    Sampaio-Dias IE; Reis-Mendes A; Costa VM; García-Mera X; Brea J; Loza MI; Pires-Lima BL; Alcoholado C; Algarra M; Rodríguez-Borges JE
    J Med Chem; 2021 May; 64(9):6209-6220. PubMed ID: 33861612
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Novel l-prolyl-l-leucylglycinamide (PLG) tripeptidomimetics based on a 2-azanorbornane scaffold as positive allosteric modulators of the D
    Sampaio-Dias IE; Sousa CA; García-Mera X; Ferreira da Costa J; Caamaño O; Rodríguez-Borges JE
    Org Biomol Chem; 2016 Nov; 14(47):11065-11069. PubMed ID: 27830864
    [TBL] [Abstract][Full Text] [Related]  

  • 6. PTML Combinatorial Model of ChEMBL Compounds Assays for Multiple Types of Cancer.
    Bediaga H; Arrasate S; González-Díaz H
    ACS Comb Sci; 2018 Nov; 20(11):621-632. PubMed ID: 30240186
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Transformation of Pro-Leu-Gly-NH2 peptidomimetic positive allosteric modulators of the dopamine D2 receptor into negative modulators.
    Bhagwanth S; Mishra S; Daya R; Mah J; Mishra RK; Johnson RL
    ACS Chem Neurosci; 2012 Apr; 3(4):274-84. PubMed ID: 22860194
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Multioutput Perturbation-Theory Machine Learning (PTML) Model of ChEMBL Data for Antiretroviral Compounds.
    Vásquez-Domínguez E; Armijos-Jaramillo VD; Tejera E; González-Díaz H
    Mol Pharm; 2019 Oct; 16(10):4200-4212. PubMed ID: 31426639
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Preclinical pharmacokinetic and toxicological evaluation of MIF-1 peptidomimetic, PAOPA: examining the pharmacology of a selective dopamine D2 receptor allosteric modulator for the treatment of schizophrenia.
    Tan ML; Basu D; Kwiecien JM; Johnson RL; Mishra RK
    Peptides; 2013 Apr; 42():89-96. PubMed ID: 23416534
    [TBL] [Abstract][Full Text] [Related]  

  • 10. PTML Model for Selection of Nanoparticles, Anticancer Drugs, and Vitamins in the Design of Drug-Vitamin Nanoparticle Release Systems for Cancer Cotherapy.
    Santana R; Zuluaga R; Gañán P; Arrasate S; Onieva E; Montemore MM; González-Díaz H
    Mol Pharm; 2020 Jul; 17(7):2612-2627. PubMed ID: 32459098
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Big Data Challenges Targeting Proteins in GPCR Signaling Pathways; Combining PTML-ChEMBL Models and [
    Diez-Alarcia R; Yáñez-Pérez V; Muneta-Arrate I; Arrasate S; Lete E; Meana JJ; González-Díaz H
    ACS Chem Neurosci; 2019 Nov; 10(11):4476-4491. PubMed ID: 31618004
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis and evaluation of novel pyridine based PLG tripeptidomimetics.
    Saitton S; Del Tredici AL; Saxin M; Stenström T; Kihlberg J; Luthman K
    Org Biomol Chem; 2008 May; 6(9):1647-54. PubMed ID: 18421399
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Design, synthesis, and dopamine receptor modulating activity of spiro bicyclic peptidomimetics of L-prolyl-L-leucyl-glycinamide.
    Khalil EM; Ojala WH; Pradhan A; Nair VD; Gleason WB; Mishra RK; Johnson RL
    J Med Chem; 1999 Feb; 42(4):628-37. PubMed ID: 10052970
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Designing nanoparticle release systems for drug-vitamin cancer co-therapy with multiplicative perturbation-theory machine learning (PTML) models.
    Santana R; Zuluaga R; Gañán P; Arrasate S; Onieva E; González-Díaz H
    Nanoscale; 2019 Nov; 11(45):21811-21823. PubMed ID: 31691701
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Design and synthesis of photoaffinity-labeling ligands of the L-prolyl-L-leucylglycinamide binding site involved in the allosteric modulation of the dopamine receptor.
    Fisher A; Mann A; Verma V; Thomas N; Mishra RK; Johnson RL
    J Med Chem; 2006 Jan; 49(1):307-17. PubMed ID: 16392815
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Stapling Amantadine to Melanostatin Neuropeptide: Discovery of Potent Positive Allosteric Modulators of the D
    Silva-Reis SC; Correia XC; Costa-Almeida HF; Pires-Lima BL; Maronde D; Costa VM; García-Mera X; Cruz L; Brea J; Loza MI; Rodríguez-Borges JE; Sampaio-Dias IE
    ACS Med Chem Lett; 2023 Dec; 14(12):1656-1663. PubMed ID: 38116429
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Development of peptidomimetic ligands of Pro-Leu-Gly-NH(2) as allosteric modulators of the dopamine D(2) receptor.
    Bhagwanth S; Mishra RK; Johnson RL
    Beilstein J Org Chem; 2013; 9():204-14. PubMed ID: 23400263
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Design, synthesis, and dopamine receptor modulating activity of diketopiperazine peptidomimetics of L-prolyl-L-leucylglycinamide.
    Baures PW; Ojala WH; Costain WJ; Ott MC; Pradhan A; Gleason WB; Mishra RK; Johnson RL
    J Med Chem; 1997 Oct; 40(22):3594-600. PubMed ID: 9357526
    [TBL] [Abstract][Full Text] [Related]  

  • 19. PTML Model of ChEMBL Compounds Assays for Vitamin Derivatives.
    Santana R; Zuluaga R; Gañán P; Arrasate S; Onieva Caracuel E; González-Díaz H
    ACS Comb Sci; 2020 Mar; 22(3):129-141. PubMed ID: 32011854
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis and allosteric modulation of the dopamine receptor by peptide analogs of L-prolyl-L-leucyl-glycinamide (PLG) modified in the L-proline or L-proline and L-leucine scaffolds.
    Ferreira da Costa J; Caamaño O; Fernández F; García-Mera X; Sampaio-Dias IE; Brea JM; Cadavid MI
    Eur J Med Chem; 2013 Nov; 69():146-58. PubMed ID: 24013414
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.