BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

173 related articles for article (PubMed ID: 33347482)

  • 1. Limited expression of non-integrating CpG-free plasmid is associated with increased nucleosome enrichment.
    Habib O; Mohd Sakri R; Ghazalli N; Chau DM; Ling KH; Abdullah S
    PLoS One; 2020; 15(12):e0244386. PubMed ID: 33347482
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The impact of polyadenylation signals on plasmid nuclease-resistance and transgene expression.
    Azzoni AR; Ribeiro SC; Monteiro GA; Prazeres DM
    J Gene Med; 2007 May; 9(5):392-402. PubMed ID: 17407167
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The effect of CpG motifs on gene expression and clearance kinetics of aerosol administered polyethylenimine (PEI)-plasmid DNA complexes in the lung.
    Lesina E; Dames P; Rudolph C
    J Control Release; 2010 Apr; 143(2):243-50. PubMed ID: 20074600
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Durable Transgene Expression Driven by CpG-Free and -Containing Promoters in Plasmid DNA with CpG-Free Backbone.
    Suzuki T; Goda T; Kamiya H
    Biol Pharm Bull; 2018; 41(9):1489-1493. PubMed ID: 30175785
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Minimal doses of a sequence-optimized transgene mediate high-level and long-term EPO expression in vivo: challenging CpG-free gene design.
    Kosovac D; Wild J; Ludwig C; Meissner S; Bauer AP; Wagner R
    Gene Ther; 2011 Feb; 18(2):189-98. PubMed ID: 20944679
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Persistence of plasmid-mediated expression of transgenes in human mesenchymal stem cells depends primarily on CpG levels of both vector and transgene.
    Bruter AV; Kandarakov OF; Belyavsky AV
    J Gene Med; 2018 Feb; 20(2-3):e3009. PubMed ID: 29424052
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The absence of CpG in plasmid DNA-chitosan polyplexes enhances transfection efficiencies and reduces inflammatory responses in murine lungs.
    Wongrakpanich A; Adamcakova-Dodd A; Xie W; Joshi VB; Mapuskar KA; Geary SM; Spitz DR; Thorne PS; Salem AK
    Mol Pharm; 2014 Mar; 11(3):1022-31. PubMed ID: 24494979
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Long-term transgene expression from plasmid DNA gene therapy vectors is negatively affected by CpG dinucleotides.
    Hodges BL; Taylor KM; Joseph MF; Bourgeois SA; Scheule RK
    Mol Ther; 2004 Aug; 10(2):269-78. PubMed ID: 15294174
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Efficient in vivo transfection and safety profile of a CpG-free and codon optimized luciferase plasmid using a cationic lipophosphoramidate in a multiple intravenous administration procedure.
    Lindberg MF; Le Gall T; Carmoy N; Berchel M; Hyde SC; Gill DR; Jaffrès PA; Lehn P; Montier T
    Biomaterials; 2015 Aug; 59():1-11. PubMed ID: 25941996
    [TBL] [Abstract][Full Text] [Related]  

  • 10. CpG-free plasmids confer reduced inflammation and sustained pulmonary gene expression.
    Hyde SC; Pringle IA; Abdullah S; Lawton AE; Davies LA; Varathalingam A; Nunez-Alonso G; Green AM; Bazzani RP; Sumner-Jones SG; Chan M; Li H; Yew NS; Cheng SH; Boyd AC; Davies JC; Griesenbach U; Porteous DJ; Sheppard DN; Munkonge FM; Alton EW; Gill DR
    Nat Biotechnol; 2008 May; 26(5):549-51. PubMed ID: 18438402
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Conventional plasmid DNAs with a CpG-containing backbone achieve durable transgene expression in mouse liver.
    Suzuki T; Wakao Y; Goda T; Kamiya H
    J Gene Med; 2020 Jan; 22(1):e3138. PubMed ID: 31696985
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Low generation PAMAM dendrimer and CpG free plasmids allow targeted and extended transgene expression in tumors after systemic delivery.
    Navarro G; Maiwald G; Haase R; Rogach AL; Wagner E; de Ilarduya CT; Ogris M
    J Control Release; 2010 Aug; 146(1):99-105. PubMed ID: 20438778
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Characterization of transgene expression and pDNA distribution of the suctioned kidney in mice.
    Oyama N; Fuchigami Y; Fumoto S; Sato M; Hagimori M; Shimizu K; Kawakami S
    Drug Deliv; 2017 Nov; 24(1):906-917. PubMed ID: 28585867
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Effect of the content of unmethylated CpG dinucleotides in plasmid DNA on the sustainability of transgene expression.
    Mitsui M; Nishikawa M; Zang L; Ando M; Hattori K; Takahashi Y; Watanabe Y; Takakura Y
    J Gene Med; 2009 May; 11(5):435-43. PubMed ID: 19291673
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Interplay of Promoter Usage and Intragenic CpG Content: Impact on GFP Reporter Gene Expression.
    Krinner S; Heitzer A; Asbach B; Wagner R
    Hum Gene Ther; 2015 Dec; 26(12):826-40. PubMed ID: 26414116
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Hydrodynamics-based procedure involves transient hyperpermeability in the hepatic cellular membrane: implication of a nonspecific process in efficient intracellular gene delivery.
    Kobayashi N; Nishikawa M; Hirata K; Takakura Y
    J Gene Med; 2004 May; 6(5):584-92. PubMed ID: 15133769
    [TBL] [Abstract][Full Text] [Related]  

  • 17. CpG-free plasmid expression cassettes for cystic fibrosis gene therapy.
    Pringle IA; Hyde SC; Connolly MM; Lawton AE; Xu B; Nunez-Alonso G; Davies LA; Sumner-Jones SG; Gill DR
    Biomaterials; 2012 Oct; 33(28):6833-42. PubMed ID: 22727465
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The use of CpG-free plasmids to mediate persistent gene expression following repeated aerosol delivery of pDNA/PEI complexes.
    Davies LA; Hyde SC; Nunez-Alonso G; Bazzani RP; Harding-Smith R; Pringle IA; Lawton AE; Abdullah S; Roberts TC; McCormick D; Sumner-Jones SG; Gill DR
    Biomaterials; 2012 Aug; 33(22):5618-27. PubMed ID: 22575838
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Transgene sequences free of CG dinucleotides lead to high level, long-term expression in the lung independent of plasmid backbone design.
    Bazzani RP; Pringle IA; Connolly MM; Davies LA; Sumner-Jones SG; Schleef M; Hyde SC; Gill DR
    Biomaterials; 2016 Jul; 93():20-26. PubMed ID: 27061267
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The impact of intragenic CpG content on gene expression.
    Bauer AP; Leikam D; Krinner S; Notka F; Ludwig C; Längst G; Wagner R
    Nucleic Acids Res; 2010 Jul; 38(12):3891-908. PubMed ID: 20203083
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.