BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

309 related articles for article (PubMed ID: 33347683)

  • 1. Formation of retromer transport carriers is disrupted by the Parkinson disease-linked Vps35 D620N variant.
    Cui Y; Yang Z; Flores-Rodriguez N; Follett J; Ariotti N; Wall AA; Parton RG; Teasdale RD
    Traffic; 2021 Apr; 22(4):123-136. PubMed ID: 33347683
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The Vps35 D620N mutation linked to Parkinson's disease disrupts the cargo sorting function of retromer.
    Follett J; Norwood SJ; Hamilton NA; Mohan M; Kovtun O; Tay S; Zhe Y; Wood SA; Mellick GD; Silburn PA; Collins BM; Bugarcic A; Teasdale RD
    Traffic; 2014 Feb; 15(2):230-44. PubMed ID: 24152121
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Retromer binding to FAM21 and the WASH complex is perturbed by the Parkinson disease-linked VPS35(D620N) mutation.
    McGough IJ; Steinberg F; Jia D; Barbuti PA; McMillan KJ; Heesom KJ; Whone AL; Caldwell MA; Billadeau DD; Rosen MK; Cullen PJ
    Curr Biol; 2014 Jul; 24(14):1670-1676. PubMed ID: 24980502
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Mutation in VPS35 associated with Parkinson's disease impairs WASH complex association and inhibits autophagy.
    Zavodszky E; Seaman MN; Moreau K; Jimenez-Sanchez M; Breusegem SY; Harbour ME; Rubinsztein DC
    Nat Commun; 2014 May; 5():3828. PubMed ID: 24819384
    [TBL] [Abstract][Full Text] [Related]  

  • 5. VPS35 and retromer dysfunction in Parkinson's disease.
    Rowlands J; Moore DJ
    Philos Trans R Soc Lond B Biol Sci; 2024 Apr; 379(1899):20220384. PubMed ID: 38368930
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The Parkinson's disease related mutant VPS35 (D620N) amplifies the LRRK2 response to endolysosomal stress.
    McCarron KR; Elcocks H; Mortiboys H; Urbé S; Clague MJ
    Biochem J; 2024 Feb; 481(4):265-278. PubMed ID: 38299383
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Mechanisms of
    Sargent D; Moore DJ
    Int Rev Mov Disord; 2021; 2():221-244. PubMed ID: 35497708
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Endosomal traffic and glutamate synapse activity are increased in VPS35 D620N mutant knock-in mouse neurons, and resistant to LRRK2 kinase inhibition.
    Kadgien CA; Kamesh A; Milnerwood AJ
    Mol Brain; 2021 Sep; 14(1):143. PubMed ID: 34530877
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The Parkinson's disease VPS35[D620N] mutation enhances LRRK2-mediated Rab protein phosphorylation in mouse and human.
    Mir R; Tonelli F; Lis P; Macartney T; Polinski NK; Martinez TN; Chou MY; Howden AJM; König T; Hotzy C; Milenkovic I; Brücke T; Zimprich A; Sammler E; Alessi DR
    Biochem J; 2018 Jun; 475(11):1861-1883. PubMed ID: 29743203
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Retromer-dependent neurotransmitter receptor trafficking to synapses is altered by the Parkinson's disease VPS35 mutation p.D620N.
    Munsie LN; Milnerwood AJ; Seibler P; Beccano-Kelly DA; Tatarnikov I; Khinda J; Volta M; Kadgien C; Cao LP; Tapia L; Klein C; Farrer MJ
    Hum Mol Genet; 2015 Mar; 24(6):1691-703. PubMed ID: 25416282
    [TBL] [Abstract][Full Text] [Related]  

  • 11. An update on cellular and molecular determinants of Parkinson's disease with emphasis on the role of the retromer complex.
    Macías-Calvio V; Fuentealba LM; Marzolo MP
    J Neurosci Res; 2021 Jan; 99(1):163-179. PubMed ID: 32633426
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Parkinson Disease-linked Vps35 R524W Mutation Impairs the Endosomal Association of Retromer and Induces α-Synuclein Aggregation.
    Follett J; Bugarcic A; Yang Z; Ariotti N; Norwood SJ; Collins BM; Parton RG; Teasdale RD
    J Biol Chem; 2016 Aug; 291(35):18283-98. PubMed ID: 27385586
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Role of the VPS35 D620N mutation in Parkinson's disease.
    Mohan M; Mellick GD
    Parkinsonism Relat Disord; 2017 Mar; 36():10-18. PubMed ID: 27964832
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Understanding the contributions of VPS35 and the retromer in neurodegenerative disease.
    Williams ET; Chen X; Otero PA; Moore DJ
    Neurobiol Dis; 2022 Aug; 170():105768. PubMed ID: 35588987
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Retromer-mediated recruitment of the WASH complex involves discrete interactions between VPS35, VPS29, and FAM21.
    Romano-Moreno M; Astorga-Simón EN; Rojas AL; Hierro A
    Protein Sci; 2024 May; 33(5):e4980. PubMed ID: 38607248
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Retromer's Role in Endosomal Trafficking and Impaired Function in Neurodegenerative Diseases.
    Follett J; Bugarcic A; Collins BM; Teasdale RD
    Curr Protein Pept Sci; 2017; 18(7):687-701. PubMed ID: 26965691
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Endosomal dysfunction in iPSC-derived neural cells from Parkinson's disease patients with VPS35 D620N.
    Bono K; Hara-Miyauchi C; Sumi S; Oka H; Iguchi Y; Okano HJ
    Mol Brain; 2020 Oct; 13(1):137. PubMed ID: 33032646
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Parkin mediates the ubiquitination of VPS35 and modulates retromer-dependent endosomal sorting.
    Williams ET; Glauser L; Tsika E; Jiang H; Islam S; Moore DJ
    Hum Mol Genet; 2018 Sep; 27(18):3189-3205. PubMed ID: 29893854
    [TBL] [Abstract][Full Text] [Related]  

  • 19. VPS35, the Retromer Complex and Parkinson's Disease.
    Williams ET; Chen X; Moore DJ
    J Parkinsons Dis; 2017; 7(2):219-233. PubMed ID: 28222538
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Retromer has a selective function in cargo sorting via endosome transport carriers.
    Cui Y; Carosi JM; Yang Z; Ariotti N; Kerr MC; Parton RG; Sargeant TJ; Teasdale RD
    J Cell Biol; 2019 Feb; 218(2):615-631. PubMed ID: 30559172
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.