BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

142 related articles for article (PubMed ID: 33348171)

  • 1. Exploiting the antiproliferative potential of spiropyrazoline oxindoles in a human ovarian cancer cell line.
    Raposo LR; Silva A; Silva D; Roma-Rodrigues C; Espadinha M; Baptista PV; Santos MMM; Fernandes AR
    Bioorg Med Chem; 2021 Jan; 30():115880. PubMed ID: 33348171
    [TBL] [Abstract][Full Text] [Related]  

  • 2. In vitro targeting of colon cancer cells using spiropyrazoline oxindoles.
    Nunes RC; Ribeiro CJA; Monteiro Â; Rodrigues CMP; Amaral JD; Santos MMM
    Eur J Med Chem; 2017 Oct; 139():168-179. PubMed ID: 28800455
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis of novel spiropyrazoline oxindoles and evaluation of cytotoxicity in cancer cell lines.
    Monteiro Â; Gonçalves LM; Santos MM
    Eur J Med Chem; 2014 May; 79():266-72. PubMed ID: 24747063
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis of substituted biphenyl methylene indolinones as apoptosis inducers and tubulin polymerization inhibitors.
    Donthiboina K; Anchi P; Sri Ramya PV; Karri S; Srinivasulu G; Godugu C; Shankaraiah N; Kamal A
    Bioorg Chem; 2019 May; 86():210-223. PubMed ID: 30716619
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Development of Benzimidazole-Substituted Spirocyclopropyl Oxindole Derivatives as Cytotoxic Agents: Tubulin Polymerization Inhibition and Apoptosis Inducing Studies.
    Sakla AP; Bazaz MR; Mahale A; Sharma P; Valapil DG; Kulkarni OP; Dandekar MP; Shankaraiah N
    ChemMedChem; 2024 Jun; 19(12):e202400052. PubMed ID: 38517377
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Molecular hybridization design and synthesis of novel spirooxindole-based MDM2 inhibitors endowed with BCL2 signaling attenuation; a step towards the next generation p53 activators.
    Lotfy G; Abdel Aziz YM; Said MM; El Ashry ESH; El Tamany ESH; Abu-Serie MM; Teleb M; Dömling A; Barakat A
    Bioorg Chem; 2021 Dec; 117():105427. PubMed ID: 34794098
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synthesis of new thiazolo-pyrrolidine-(spirooxindole) tethered to 3-acylindole as anticancer agents.
    Islam MS; Ghawas HM; El-Senduny FF; Al-Majid AM; Elshaier YAMM; Badria FA; Barakat A
    Bioorg Chem; 2019 Feb; 82():423-430. PubMed ID: 30508794
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Combined Scaffold Evaluation and Systems-Level Transcriptome-Based Analysis for Accelerated Lead Optimization Reveals Ribosomal Targeting Spirooxindole Cyclopropanes.
    Rodriguez KX; Howe EN; Bacher EP; Burnette M; Meloche JL; Meisel J; Schnepp P; Tan X; Chang M; Zartman J; Zhang S; Ashfeld BL
    ChemMedChem; 2019 Sep; 14(18):1653-1661. PubMed ID: 31140738
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis of spiro-tetrahydrothiopyran-oxindoles by Michael-aldol cascade reactions: discovery of potential P53-MDM2 inhibitors with good antitumor activity.
    Wang S; Chen S; Guo Z; He S; Zhang F; Liu X; Chen W; Zhang S; Sheng C
    Org Biomol Chem; 2018 Jan; 16(4):625-634. PubMed ID: 29302672
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Design, Synthesis, and Biological Evaluation of Novel Thiazolyl Substituted Bis-pyrazole Oxime Derivatives with Potent Antitumor Activities by Selectively Inducing Apoptosis and ROS in Cancer Cells.
    Xiong B; Chen S; Zhu P; Huang M; Gao W; Zhu R; Qian J; Peng Y; Zhang Y; Dai H; Ling Y
    Med Chem; 2019; 15(7):743-754. PubMed ID: 30147012
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Antitumor properties of certain spirooxindoles towards hepatocellular carcinoma endowed with antioxidant activity.
    Al-Rashood ST; Hamed AR; Hassan GS; Alkahtani HM; Almehizia AA; Alharbi A; Al-Sanea MM; Eldehna WM
    J Enzyme Inhib Med Chem; 2020 Dec; 35(1):831-839. PubMed ID: 32208781
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Discovery of new LXRβ agonists as glioblastoma inhibitors.
    Chen H; Chen Z; Zhang Z; Li Y; Zhang S; Jiang F; Wei J; Ding P; Zhou H; Gu Q; Xu J
    Eur J Med Chem; 2020 May; 194():112240. PubMed ID: 32248003
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Novel pyrazolo[3,4-d]pyrimidine derivatives inhibit human cancer cell proliferation and induce apoptosis by ROS generation.
    Gaonkar S; Savanur MA; Nadaf AA; Najare MS; Mantur S; Garbhagudi M; Mulla SI; Khazi IAM
    Arch Pharm (Weinheim); 2020 Apr; 353(4):e1900296. PubMed ID: 32073686
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis of New Bis-Spiropyrazoles as Antitumor Agents under Ultrasound Irradiation.
    Abdel Hafez NA; Hassaneen HME; Farghaly TA; Riyadh SM; Elzahabi HSA
    Mini Rev Med Chem; 2018; 18(7):631-637. PubMed ID: 28901853
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Design, combinatorial synthesis and biological evaluations of novel 3-amino-1'-((1-aryl-1H-1,2,3-triazol-5-yl)methyl)-2'-oxospiro[benzo[a] pyrano[2,3-c]phenazine-1,3'-indoline]-2-carbonitrile antitumor hybrid molecules.
    Lu Y; Wang L; Wang X; Xi T; Liao J; Wang Z; Jiang F
    Eur J Med Chem; 2017 Jul; 135():125-141. PubMed ID: 28441581
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Design, synthesis and biological evaluation of novel steroidal spiro-oxindoles as potent antiproliferative agents.
    Yu B; Shi XJ; Qi PP; Yu DQ; Liu HM
    J Steroid Biochem Mol Biol; 2014 May; 141():121-34. PubMed ID: 24508598
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Fe
    Maddela S; Makula A; Galigniana MD; Parambi DGT; Federicci F; Mazaira G; Hendawy OM; Dev S; Mathew GE; Mathew B
    Arch Pharm (Weinheim); 2019 Jan; 352(1):e1800174. PubMed ID: 30485473
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis and in vitro evaluation of novel spiroketopyrazoles as acetyl-CoA carboxylase inhibitors and potential antitumor agents.
    Huang T; Wu X; Yan S; Liu T; Yin X
    Eur J Med Chem; 2021 Feb; 212():113036. PubMed ID: 33276990
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Reliability of Click Chemistry on Drug Discovery: A Personal Account.
    Shankaraiah N; Sakla AP; Laxmikeshav K; Tokala R
    Chem Rec; 2020 Apr; 20(4):253-272. PubMed ID: 31419056
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Inhibition of p53-Murine Double Minute 2 (MDM2) Interactions with 3,3'-Spirocyclopentene Oxindole Derivatives.
    Gicquel M; Gomez C; Garcia Alvarez MC; Pamlard O; Guérineau V; Jacquet E; Bignon J; Voituriez A; Marinetti A
    J Med Chem; 2018 Oct; 61(20):9386-9392. PubMed ID: 30221935
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.