BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

317 related articles for article (PubMed ID: 33353886)

  • 1. The Ercc
    Wong A; Kieu T; Robbins PD
    Aging (Albany NY); 2020 Dec; 12(24):24481-24483. PubMed ID: 33353886
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Tissue specificity of senescent cell accumulation during physiologic and accelerated aging of mice.
    Yousefzadeh MJ; Zhao J; Bukata C; Wade EA; McGowan SJ; Angelini LA; Bank MP; Gurkar AU; McGuckian CA; Calubag MF; Kato JI; Burd CE; Robbins PD; Niedernhofer LJ
    Aging Cell; 2020 Mar; 19(3):e13094. PubMed ID: 31981461
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Deficiency in the DNA repair protein ERCC1 triggers a link between senescence and apoptosis in human fibroblasts and mouse skin.
    Kim DE; Dollé MET; Vermeij WP; Gyenis A; Vogel K; Hoeijmakers JHJ; Wiley CD; Davalos AR; Hasty P; Desprez PY; Campisi J
    Aging Cell; 2020 Mar; 19(3):e13072. PubMed ID: 31737985
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Spontaneous DNA damage to the nuclear genome promotes senescence, redox imbalance and aging.
    Robinson AR; Yousefzadeh MJ; Rozgaja TA; Wang J; Li X; Tilstra JS; Feldman CH; Gregg SQ; Johnson CH; Skoda EM; Frantz MC; Bell-Temin H; Pope-Varsalona H; Gurkar AU; Nasto LA; Robinson RAS; Fuhrmann-Stroissnigg H; Czerwinska J; McGowan SJ; Cantu-Medellin N; Harris JB; Maniar S; Ross MA; Trussoni CE; LaRusso NF; Cifuentes-Pagano E; Pagano PJ; Tudek B; Vo NV; Rigatti LH; Opresko PL; Stolz DB; Watkins SC; Burd CE; Croix CMS; Siuzdak G; Yates NA; Robbins PD; Wang Y; Wipf P; Kelley EE; Niedernhofer LJ
    Redox Biol; 2018 Jul; 17():259-273. PubMed ID: 29747066
    [TBL] [Abstract][Full Text] [Related]  

  • 5. DNA damage drives accelerated bone aging via an NF-κB-dependent mechanism.
    Chen Q; Liu K; Robinson AR; Clauson CL; Blair HC; Robbins PD; Niedernhofer LJ; Ouyang H
    J Bone Miner Res; 2013 May; 28(5):1214-28. PubMed ID: 23281008
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A mouse model of accelerated liver aging caused by a defect in DNA repair.
    Gregg SQ; Gutiérrez V; Robinson AR; Woodell T; Nakao A; Ross MA; Michalopoulos GK; Rigatti L; Rothermel CE; Kamileri I; Garinis GA; Stolz DB; Niedernhofer LJ
    Hepatology; 2012 Feb; 55(2):609-21. PubMed ID: 21953681
    [TBL] [Abstract][Full Text] [Related]  

  • 7. ATM is a key driver of NF-κB-dependent DNA-damage-induced senescence, stem cell dysfunction and aging.
    Zhao J; Zhang L; Lu A; Han Y; Colangelo D; Bukata C; Scibetta A; Yousefzadeh MJ; Li X; Gurkar AU; McGowan SJ; Angelini L; O'Kelly R; Li H; Corbo L; Sano T; Nick H; Pola E; Pilla SPS; Ladiges WC; Vo N; Huard J; Niedernhofer LJ; Robbins PD
    Aging (Albany NY); 2020 Mar; 12(6):4688-4710. PubMed ID: 32201398
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Identification of microRNAs dysregulated in cellular senescence driven by endogenous genotoxic stress.
    Nidadavolu LS; Niedernhofer LJ; Khan SA
    Aging (Albany NY); 2013 Jun; 5(6):460-73. PubMed ID: 23852002
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The Achilles' heel of senescent cells: from transcriptome to senolytic drugs.
    Zhu Y; Tchkonia T; Pirtskhalava T; Gower AC; Ding H; Giorgadze N; Palmer AK; Ikeno Y; Hubbard GB; Lenburg M; O'Hara SP; LaRusso NF; Miller JD; Roos CM; Verzosa GC; LeBrasseur NK; Wren JD; Farr JN; Khosla S; Stout MB; McGowan SJ; Fuhrmann-Stroissnigg H; Gurkar AU; Zhao J; Colangelo D; Dorronsoro A; Ling YY; Barghouthy AS; Navarro DC; Sano T; Robbins PD; Niedernhofer LJ; Kirkland JL
    Aging Cell; 2015 Aug; 14(4):644-58. PubMed ID: 25754370
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Increased insulin sensitivity and diminished pancreatic beta-cell function in DNA repair deficient Ercc1
    Huerta Guevara AP; McGowan SJ; Kazantzis M; Stallons TR; Sano T; Mulder NL; Jurdzinski A; van Dijk TH; Eggen BJL; Jonker JW; Niedernhofer LJ; Kruit JK
    Metabolism; 2021 Apr; 117():154711. PubMed ID: 33493548
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Accelerated aging of intervertebral discs in a mouse model of progeria.
    Vo N; Seo HY; Robinson A; Sowa G; Bentley D; Taylor L; Studer R; Usas A; Huard J; Alber S; Watkins SC; Lee J; Coehlo P; Wang D; Loppini M; Robbins PD; Niedernhofer LJ; Kang J
    J Orthop Res; 2010 Dec; 28(12):1600-7. PubMed ID: 20973062
    [TBL] [Abstract][Full Text] [Related]  

  • 12. mTOR signaling plays a critical role in the defects observed in muscle-derived stem/progenitor cells isolated from a murine model of accelerated aging.
    Takayama K; Kawakami Y; Lavasani M; Mu X; Cummins JH; Yurube T; Kuroda R; Kurosaka M; Fu FH; Robbins PD; Niedernhofer LJ; Huard J
    J Orthop Res; 2017 Jul; 35(7):1375-1382. PubMed ID: 27572850
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Transcriptional profiling reveals progeroid Ercc1(-/Δ) mice as a model system for glomerular aging.
    Schermer B; Bartels V; Frommolt P; Habermann B; Braun F; Schultze JL; Roodbergen M; Hoeijmakers JH; Schumacher B; Nürnberg P; Dollé ME; Benzing T; Müller RU; Kurschat CE
    BMC Genomics; 2013 Aug; 14():559. PubMed ID: 23947592
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Genomic instability in the naturally and prematurely aged myocardium.
    De Majo F; Martens L; Hegenbarth JC; Rühle F; Hamczyk MR; Nevado RM; Andrés V; Hilbold E; Bär C; Thum T; de Boer M; Duncker DJ; Schroen B; Armand AS; Stoll M; De Windt LJ
    Proc Natl Acad Sci U S A; 2021 Sep; 118(36):. PubMed ID: 34465617
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The age-related expression decline of ERCC1 and XPF for forensic age estimation: A preliminary study.
    Deng XD; Gao Q; Zhang W; Zhang B; Ma Y; Zhang LX; Muer C; Xie Y; Liu Y
    J Forensic Leg Med; 2017 Jul; 49():15-19. PubMed ID: 28486142
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Involvement of ERCC1 in the pathogenesis of osteoarthritis through the modulation of apoptosis and cellular senescence.
    Takayama K; Kawakami Y; Lee S; Greco N; Lavasani M; Mifune Y; Cummins JH; Yurube T; Kuroda R; Kurosaka M; Fu FH; Huard J
    J Orthop Res; 2014 Oct; 32(10):1326-32. PubMed ID: 24964749
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Identification of HSP90 inhibitors as a novel class of senolytics.
    Fuhrmann-Stroissnigg H; Ling YY; Zhao J; McGowan SJ; Zhu Y; Brooks RW; Grassi D; Gregg SQ; Stripay JL; Dorronsoro A; Corbo L; Tang P; Bukata C; Ring N; Giacca M; Li X; Tchkonia T; Kirkland JL; Niedernhofer LJ; Robbins PD
    Nat Commun; 2017 Sep; 8(1):422. PubMed ID: 28871086
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Genotoxic stress accelerates age-associated degenerative changes in intervertebral discs.
    Nasto LA; Wang D; Robinson AR; Clauson CL; Ngo K; Dong Q; Roughley P; Epperly M; Huq SM; Pola E; Sowa G; Robbins PD; Kang J; Niedernhofer LJ; Vo NV
    Mech Ageing Dev; 2013; 134(1-2):35-42. PubMed ID: 23262094
    [TBL] [Abstract][Full Text] [Related]  

  • 19. ERCC1-deficient cells and mice are hypersensitive to lipid peroxidation.
    Czerwińska J; Nowak M; Wojtczak P; Dziuban-Lech D; Cieśla JM; Kołata D; Gajewska B; Barańczyk-Kuźma A; Robinson AR; Shane HL; Gregg SQ; Rigatti LH; Yousefzadeh MJ; Gurkar AU; McGowan SJ; Kosicki K; Bednarek M; Zarakowska E; Gackowski D; Oliński R; Speina E; Niedernhofer LJ; Tudek B
    Free Radic Biol Med; 2018 Aug; 124():79-96. PubMed ID: 29860127
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Premature aging-related peripheral neuropathy in a mouse model of progeria.
    Goss JR; Stolz DB; Robinson AR; Zhang M; Arbujas N; Robbins PD; Glorioso JC; Niedernhofer LJ
    Mech Ageing Dev; 2011 Aug; 132(8-9):437-42. PubMed ID: 21596054
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.