BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

346 related articles for article (PubMed ID: 33358111)

  • 1. Targeting the Mevalonate Pathway in Cancer.
    Juarez D; Fruman DA
    Trends Cancer; 2021 Jun; 7(6):525-540. PubMed ID: 33358111
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Secretion of apolipoprotein E by brain glia requires protein prenylation and is suppressed by statins.
    Naidu A; Xu Q; Catalano R; Cordell B
    Brain Res; 2002 Dec; 958(1):100-11. PubMed ID: 12468034
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Statins inhibit blastocyst formation by preventing geranylgeranylation.
    Alarcon VB; Marikawa Y
    Mol Hum Reprod; 2016 May; 22(5):350-63. PubMed ID: 26908642
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Targeting the mevalonate cascade as a new therapeutic approach in heart disease, cancer and pulmonary disease.
    Yeganeh B; Wiechec E; Ande SR; Sharma P; Moghadam AR; Post M; Freed DH; Hashemi M; Shojaei S; Zeki AA; Ghavami S
    Pharmacol Ther; 2014 Jul; 143(1):87-110. PubMed ID: 24582968
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The mevalonate synthesis pathway as a therapeutic target in cancer.
    Andela VB; Pirri M; Schwarz EM; Puzas EJ; O'Keefe RJ; Rosenblatt JD; Rosier RN
    Clin Orthop Relat Res; 2003 Oct; (415 Suppl):S59-66. PubMed ID: 14600593
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Efficient use of exogenous isoprenols for protein isoprenylation by MDA-MB-231 cells is regulated independently of the mevalonate pathway.
    Onono F; Subramanian T; Sunkara M; Subramanian KL; Spielmann HP; Morris AJ
    J Biol Chem; 2013 Sep; 288(38):27444-27455. PubMed ID: 23908355
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Novel aspects of mevalonate pathway inhibitors as antitumor agents.
    Thurnher M; Nussbaumer O; Gruenbacher G
    Clin Cancer Res; 2012 Jul; 18(13):3524-31. PubMed ID: 22529099
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Inhibition of geranylgeranylation mediates sensitivity to CHOP-induced cell death of DLBCL cell lines.
    Ageberg M; Rydström K; Lindén O; Linderoth J; Jerkeman M; Drott K
    Exp Cell Res; 2011 May; 317(8):1179-91. PubMed ID: 21324313
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Anti-tumor effects of mevalonate pathway inhibition in ovarian cancer.
    Göbel A; Zinna VM; Dell'Endice S; Jaschke N; Kuhlmann JD; Wimberger P; Rachner TD
    BMC Cancer; 2020 Jul; 20(1):703. PubMed ID: 32727400
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Inhibition of geranylgeranylation mediates the effects of 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase inhibitors on microglia.
    Bi X; Baudry M; Liu J; Yao Y; Fu L; Brucher F; Lynch G
    J Biol Chem; 2004 Nov; 279(46):48238-45. PubMed ID: 15364922
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Simvastatin inhibits TGFβ1-induced fibronectin in human airway fibroblasts.
    Schaafsma D; McNeill KD; Mutawe MM; Ghavami S; Unruh H; Jacques E; Laviolette M; Chakir J; Halayko AJ
    Respir Res; 2011 Aug; 12(1):113. PubMed ID: 21864337
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Effects of statins and farnesyltransferase inhibitors on the development and progression of cancer.
    Graaf MR; Richel DJ; van Noorden CJ; Guchelaar HJ
    Cancer Treat Rev; 2004 Nov; 30(7):609-41. PubMed ID: 15531395
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Mevalonate Cascade Inhibition by Simvastatin Induces the Intrinsic Apoptosis Pathway via Depletion of Isoprenoids in Tumor Cells.
    Alizadeh J; Zeki AA; Mirzaei N; Tewary S; Rezaei Moghadam A; Glogowska A; Nagakannan P; Eftekharpour E; Wiechec E; Gordon JW; Xu FY; Field JT; Yoneda KY; Kenyon NJ; Hashemi M; Hatch GM; Hombach-Klonisch S; Klonisch T; Ghavami S
    Sci Rep; 2017 Mar; 7():44841. PubMed ID: 28344327
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Inhibition of farnesyl pyrophosphate (FPP) and/or geranylgeranyl pyrophosphate (GGPP) biosynthesis and its implication in the treatment of cancers.
    Waller DD; Park J; Tsantrizos YS
    Crit Rev Biochem Mol Biol; 2019 Feb; 54(1):41-60. PubMed ID: 30773935
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Statins, Mevalonate Pathway and its Intermediate Products in Placental Development and Preeclampsia.
    Ermini L; Post M; Caniggia I
    Curr Mol Pharmacol; 2017; 10(2):152-160. PubMed ID: 26758951
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Mevalonate Cascade and its Regulation in Cholesterol Metabolism in Different Tissues in Health and Disease.
    Hashemi M; Hoshyar R; Ande SR; Chen QM; Solomon C; Zuse A; Naderi M
    Curr Mol Pharmacol; 2017; 10(1):13-26. PubMed ID: 26758949
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Statin-induced depletion of geranylgeranyl pyrophosphate inhibits cell proliferation by a novel pathway of Skp2 degradation.
    Vosper J; Masuccio A; Kullmann M; Ploner C; Geley S; Hengst L
    Oncotarget; 2015 Feb; 6(5):2889-902. PubMed ID: 25605247
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Simvastatin-mediated enhancement of long-term potentiation is driven by farnesyl-pyrophosphate depletion and inhibition of farnesylation.
    Mans RA; McMahon LL; Li L
    Neuroscience; 2012 Jan; 202():1-9. PubMed ID: 22192838
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Key Enzymes for the Mevalonate Pathway in the Cardiovascular System.
    Zhang C; Jin DD; Wang XY; Lou L; Yang J
    J Cardiovasc Pharmacol; 2021 Feb; 77(2):142-152. PubMed ID: 33538531
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mevalonate Pathway Regulates Cell Size Homeostasis and Proteostasis through Autophagy.
    Miettinen TP; Björklund M
    Cell Rep; 2015 Dec; 13(11):2610-2620. PubMed ID: 26686643
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 18.