276 related articles for article (PubMed ID: 33361160)
1. CRAC channel opening is determined by a series of Orai1 gating checkpoints in the transmembrane and cytosolic regions.
Tiffner A; Schober R; Höglinger C; Bonhenry D; Pandey S; Lunz V; Sallinger M; Frischauf I; Fahrner M; Lindinger S; Maltan L; Berlansky S; Stadlbauer M; Schindl R; Ettrich R; Romanin C; Derler I
J Biol Chem; 2021; 296():100224. PubMed ID: 33361160
[TBL] [Abstract][Full Text] [Related]
2. A dual mechanism promotes switching of the Stormorken STIM1 R304W mutant into the activated state.
Fahrner M; Stadlbauer M; Muik M; Rathner P; Stathopulos P; Ikura M; Müller N; Romanin C
Nat Commun; 2018 Feb; 9(1):825. PubMed ID: 29483506
[TBL] [Abstract][Full Text] [Related]
3. Pore properties of Orai1 calcium channel dimers and their activation by the STIM1 ER calcium sensor.
Cai X; Nwokonko RM; Loktionova NA; Abdulqadir R; Baraniak JH; Wang Y; Trebak M; Zhou Y; Gill DL
J Biol Chem; 2018 Aug; 293(33):12962-12974. PubMed ID: 29954946
[TBL] [Abstract][Full Text] [Related]
4. STIM1-Orai1 interactions and Orai1 conformational changes revealed by live-cell FRET microscopy.
Navarro-Borelly L; Somasundaram A; Yamashita M; Ren D; Miller RJ; Prakriya M
J Physiol; 2008 Nov; 586(22):5383-401. PubMed ID: 18832420
[TBL] [Abstract][Full Text] [Related]
5. Authentic CRAC channel activity requires STIM1 and the conserved portion of the Orai N terminus.
Derler I; Butorac C; Krizova A; Stadlbauer M; Muik M; Fahrner M; Frischauf I; Romanin C
J Biol Chem; 2018 Jan; 293(4):1259-1270. PubMed ID: 29237734
[TBL] [Abstract][Full Text] [Related]
6. The Orai Pore Opening Mechanism.
Tiffner A; Maltan L; Weiß S; Derler I
Int J Mol Sci; 2021 Jan; 22(2):. PubMed ID: 33430308
[TBL] [Abstract][Full Text] [Related]
7. ORAI1 channel gating and selectivity is differentially altered by natural mutations in the first or third transmembrane domain.
Bulla M; Gyimesi G; Kim JH; Bhardwaj R; Hediger MA; Frieden M; Demaurex N
J Physiol; 2019 Jan; 597(2):561-582. PubMed ID: 30382595
[TBL] [Abstract][Full Text] [Related]
8. Communication between N terminus and loop2 tunes Orai activation.
Fahrner M; Pandey SK; Muik M; Traxler L; Butorac C; Stadlbauer M; Zayats V; Krizova A; Plenk P; Frischauf I; Schindl R; Gruber HJ; Hinterdorfer P; Ettrich R; Romanin C; Derler I
J Biol Chem; 2018 Jan; 293(4):1271-1285. PubMed ID: 29237733
[TBL] [Abstract][Full Text] [Related]
9. A novel STIM1-Orai1 gating interface essential for CRAC channel activation.
Butorac C; Muik M; Derler I; Stadlbauer M; Lunz V; Krizova A; Lindinger S; Schober R; Frischauf I; Bhardwaj R; Hediger MA; Groschner K; Romanin C
Cell Calcium; 2019 May; 79():57-67. PubMed ID: 30831274
[TBL] [Abstract][Full Text] [Related]
10. Ca
Bhardwaj R; Augustynek BS; Ercan-Herbst E; Kandasamy P; Seedorf M; Peinelt C; Hediger MA
Cell Physiol Biochem; 2020 Mar; 54(2):252-270. PubMed ID: 32176842
[TBL] [Abstract][Full Text] [Related]
11. Molecular mechanisms of STIM/Orai communication.
Derler I; Jardin I; Romanin C
Am J Physiol Cell Physiol; 2016 Apr; 310(8):C643-62. PubMed ID: 26825122
[TBL] [Abstract][Full Text] [Related]
12. STIM1 activates CRAC channels through rotation of the pore helix to open a hydrophobic gate.
Yamashita M; Yeung PS; Ing CE; McNally BA; Pomès R; Prakriya M
Nat Commun; 2017 Feb; 8():14512. PubMed ID: 28220789
[TBL] [Abstract][Full Text] [Related]
13. Essential role of N-terminal SAM regions in STIM1 multimerization and function.
Sallinger M; Humer C; Ong HL; Narayanasamy S; Lin QT; Fahrner M; Grabmayr H; Berlansky S; Choi S; Schmidt T; Maltan L; Atzgerstorfer L; Niederwieser M; Frischauf I; Romanin C; Stathopulos PB; Ambudkar I; Leitner R; Bonhenry D; Schindl R
Proc Natl Acad Sci U S A; 2024 May; 121(21):e2318874121. PubMed ID: 38753510
[TBL] [Abstract][Full Text] [Related]
14. Structural and Mechanistic Insights of CRAC Channel as a Drug Target in Autoimmune Disorder.
Bhuvaneshwari S; Sankaranarayanan K
Curr Drug Targets; 2020; 21(1):55-75. PubMed ID: 31556856
[TBL] [Abstract][Full Text] [Related]
15. The STIM1-binding site nexus remotely controls Orai1 channel gating.
Zhou Y; Cai X; Loktionova NA; Wang X; Nwokonko RM; Wang X; Wang Y; Rothberg BS; Trebak M; Gill DL
Nat Commun; 2016 Dec; 7():13725. PubMed ID: 27929067
[TBL] [Abstract][Full Text] [Related]
16. Transmembrane helix connectivity in Orai1 controls two gates for calcium-dependent transcription.
Frischauf I; Litviňuková M; Schober R; Zayats V; Svobodová B; Bonhenry D; Lunz V; Cappello S; Tociu L; Reha D; Stallinger A; Hochreiter A; Pammer T; Butorac C; Muik M; Groschner K; Bogeski I; Ettrich RH; Romanin C; Schindl R
Sci Signal; 2017 Nov; 10(507):. PubMed ID: 29184031
[TBL] [Abstract][Full Text] [Related]
17. Differential roles of the C and N termini of Orai1 protein in interacting with stromal interaction molecule 1 (STIM1) for Ca2+ release-activated Ca2+ (CRAC) channel activation.
Zheng H; Zhou MH; Hu C; Kuo E; Peng X; Hu J; Kuo L; Zhang SL
J Biol Chem; 2013 Apr; 288(16):11263-72. PubMed ID: 23447534
[TBL] [Abstract][Full Text] [Related]
18. Distinct gating mechanism of SOC channel involving STIM-Orai coupling and an intramolecular interaction of Orai in
Kim KM; Wijerathne T; Hur JH; Kang UJ; Kim IH; Kweon YC; Lee AR; Jeong SJ; Lee SK; Lee YY; Sim BW; Lee JH; Baig C; Kim SU; Chang KT; Lee KP; Park CY
Proc Natl Acad Sci U S A; 2018 May; 115(20):E4623-E4632. PubMed ID: 29712850
[TBL] [Abstract][Full Text] [Related]
19. The action of selective CRAC channel blockers is affected by the Orai pore geometry.
Derler I; Schindl R; Fritsch R; Heftberger P; Riedl MC; Begg M; House D; Romanin C
Cell Calcium; 2013 Feb; 53(2):139-51. PubMed ID: 23218667
[TBL] [Abstract][Full Text] [Related]
20. Conformational Changes in the Orai1 C-Terminus Evoked by STIM1 Binding.
Tirado-Lee L; Yamashita M; Prakriya M
PLoS One; 2015; 10(6):e0128622. PubMed ID: 26035642
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
