These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

182 related articles for article (PubMed ID: 33361334)

  • 21. A genome-scale CRISPR-Cas9 screening in myeloma cells identifies regulators of immunomodulatory drug sensitivity.
    Liu J; Song T; Zhou W; Xing L; Wang S; Ho M; Peng Z; Tai YT; Hideshima T; Anderson KC; Cang Y
    Leukemia; 2019 Jan; 33(1):171-180. PubMed ID: 30026574
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Humanized cereblon mice revealed two distinct therapeutic pathways of immunomodulatory drugs.
    Gemechu Y; Millrine D; Hashimoto S; Prakash J; Sanchenkova K; Metwally H; Gyanu P; Kang S; Kishimoto T
    Proc Natl Acad Sci U S A; 2018 Nov; 115(46):11802-11807. PubMed ID: 30373817
    [TBL] [Abstract][Full Text] [Related]  

  • 23. USP15 antagonizes CRL4
    Nguyen TV
    Proc Natl Acad Sci U S A; 2021 Oct; 118(40):. PubMed ID: 34583995
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Targeting the CK1α/CBX4 axis for metastasis in osteosarcoma.
    Wang X; Qin G; Liang X; Wang W; Wang Z; Liao D; Zhong L; Zhang R; Zeng YX; Wu Y; Kang T
    Nat Commun; 2020 Feb; 11(1):1141. PubMed ID: 32111827
    [TBL] [Abstract][Full Text] [Related]  

  • 25. The IMiD target CRBN determines HSP90 activity toward transmembrane proteins essential in multiple myeloma.
    Heider M; Eichner R; Stroh J; Morath V; Kuisl A; Zecha J; Lawatscheck J; Baek K; Garz AK; Rudelius M; Deuschle FC; Keller U; Lemeer S; Verbeek M; Götze KS; Skerra A; Weber WA; Buchner J; Schulman BA; Kuster B; Fernández-Sáiz V; Bassermann F
    Mol Cell; 2021 Mar; 81(6):1170-1186.e10. PubMed ID: 33571422
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Differential abundance of CK1α provides selectivity for pharmacological CK1α activators to target WNT-dependent tumors.
    Li B; Orton D; Neitzel LR; Astudillo L; Shen C; Long J; Chen X; Kirkbride KC; Doundoulakis T; Guerra ML; Zaias J; Fei DL; Rodriguez-Blanco J; Thorne C; Wang Z; Jin K; Nguyen DM; Sands LR; Marchetti F; Abreu MT; Cobb MH; Capobianco AJ; Lee E; Robbins DJ
    Sci Signal; 2017 Jun; 10(485):. PubMed ID: 28655862
    [TBL] [Abstract][Full Text] [Related]  

  • 27. YAP-dependent ubiquitination and degradation of β-catenin mediates inhibition of Wnt signalling induced by Physalin F in colorectal cancer.
    Chen C; Zhu D; Zhang H; Han C; Xue G; Zhu T; Luo J; Kong L
    Cell Death Dis; 2018 May; 9(6):591. PubMed ID: 29789528
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Exploiting the MDM2-CK1α protein-protein interface to develop novel biologics that induce UBL-kinase-modification and inhibit cell growth.
    Huart AS; MacLaine NJ; Narayan V; Hupp TR
    PLoS One; 2012; 7(8):e43391. PubMed ID: 22916255
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Lenalidomide induces ubiquitination and degradation of CK1α in del(5q) MDS.
    Krönke J; Fink EC; Hollenbach PW; MacBeth KJ; Hurst SN; Udeshi ND; Chamberlain PP; Mani DR; Man HW; Gandhi AK; Svinkina T; Schneider RK; McConkey M; Järås M; Griffiths E; Wetzler M; Bullinger L; Cathers BE; Carr SA; Chopra R; Ebert BL
    Nature; 2015 Jul; 523(7559):183-188. PubMed ID: 26131937
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Akt Phosphorylates Wnt Coactivator and Chromatin Effector Pygo2 at Serine 48 to Antagonize Its Ubiquitin/Proteasome-mediated Degradation.
    Li Q; Li Y; Gu B; Fang L; Zhou P; Bao S; Huang L; Dai X
    J Biol Chem; 2015 Aug; 290(35):21553-67. PubMed ID: 26170450
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Chemical Inactivation of the E3 Ubiquitin Ligase Cereblon by Pomalidomide-based Homo-PROTACs.
    Lindner S; Steinebach C; Kehm H; Mangold M; Gütschow M; Krönke J
    J Vis Exp; 2019 May; (147):. PubMed ID: 31157769
    [TBL] [Abstract][Full Text] [Related]  

  • 32. The adaptor molecule CIN85 regulates Syk tyrosine kinase level by activating the ubiquitin-proteasome degradation pathway.
    Peruzzi G; Molfetta R; Gasparrini F; Vian L; Morrone S; Piccoli M; Frati L; Santoni A; Paolini R
    J Immunol; 2007 Aug; 179(4):2089-96. PubMed ID: 17675467
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Immunomodulatory drugs activate NK cells via both Zap-70 and cereblon-dependent pathways.
    Hideshima T; Ogiya D; Liu J; Harada T; Kurata K; Bae J; Massefski W; Anderson KC
    Leukemia; 2021 Jan; 35(1):177-188. PubMed ID: 32238854
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Aromatase is a novel neosubstrate of cereblon responsible for immunomodulatory drug-induced thrombocytopenia.
    Tochigi T; Miyamoto T; Hatakeyama K; Sakoda T; Ishihara D; Irifune H; Shima T; Kato K; Maeda T; Ito T; Handa H; Akashi K; Kikushige Y
    Blood; 2020 Jun; 135(24):2146-2158. PubMed ID: 32219443
    [TBL] [Abstract][Full Text] [Related]  

  • 35. The CK1α Activator Pyrvinium Enhances the Catalytic Efficiency (
    Shen C; Li B; Astudillo L; Deutscher MP; Cobb MH; Capobianco AJ; Lee E; Robbins DJ
    Biochemistry; 2019 Dec; 58(51):5102-5106. PubMed ID: 31820934
    [TBL] [Abstract][Full Text] [Related]  

  • 36. CK1α protects WAVE from degradation to regulate cell shape and motility in the immune response.
    Hirschhäuser A; van Cann M; Bogdan S
    J Cell Sci; 2021 Dec; 134(23):. PubMed ID: 34730182
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Jade-1S phosphorylation induced by CK1α contributes to cell cycle progression.
    Borgal L; Rinschen MM; Dafinger C; Liebrecht VI; Abken H; Benzing T; Schermer B
    Cell Cycle; 2016; 15(8):1034-45. PubMed ID: 26919559
    [TBL] [Abstract][Full Text] [Related]  

  • 38. An IMiD-induced SALL4 degron system for selective degradation of target proteins.
    Yamanaka S; Shoya Y; Matsuoka S; Nishida-Fukuda H; Shibata N; Sawasaki T
    Commun Biol; 2020 Sep; 3(1):515. PubMed ID: 32948804
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Suppression of casein kinase 1alpha in melanoma cells induces a switch in beta-catenin signaling to promote metastasis.
    Sinnberg T; Menzel M; Kaesler S; Biedermann T; Sauer B; Nahnsen S; Schwarz M; Garbe C; Schittek B
    Cancer Res; 2010 Sep; 70(17):6999-7009. PubMed ID: 20699366
    [TBL] [Abstract][Full Text] [Related]  

  • 40. The novel cereblon modulator CC-885 inhibits mitophagy via selective degradation of BNIP3L.
    Hao BB; Li XJ; Jia XL; Wang YX; Zhai LH; Li DZ; Liu J; Zhang D; Chen YL; Xu YH; Lee SK; Xu GF; Chen XH; Dang YJ; Liu B; Tan MJ
    Acta Pharmacol Sin; 2020 Sep; 41(9):1246-1254. PubMed ID: 32210356
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 10.