These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

168 related articles for article (PubMed ID: 33372040)

  • 1. Differential Regulation of Cancer Progression by CDK4/6 Plays a Central Role in DNA Replication and Repair Pathways.
    Dai M; Boudreault J; Wang N; Poulet S; Daliah G; Yan G; Moamer A; Burgos SA; Sabri S; Ali S; Lebrun JJ
    Cancer Res; 2021 Mar; 81(5):1332-1346. PubMed ID: 33372040
    [TBL] [Abstract][Full Text] [Related]  

  • 2. 4-Acetylantroquinonol B induced DNA damage response signaling and apoptosis via suppressing CDK2/CDK4 expression in triple negative breast cancer cells.
    Satriyo PB; Su CM; Ong JR; Huang WC; Fong IH; Lin CC; Aryandono T; Haryana SM; Deng L; Huang CC; Tzeng YM; Chao TY; Liu HW; Yeh CT
    Toxicol Appl Pharmacol; 2021 Jul; 422():115493. PubMed ID: 33727089
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Modulated expression of genes encoding estrogen metabolizing enzymes by G1-phase cyclin-dependent kinases 6 and 4 in human breast cancer cells.
    Jia Y; Domenico J; Swasey C; Wang M; Gelfand EW; Lucas JJ
    PLoS One; 2014; 9(5):e97448. PubMed ID: 24848372
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Loss of the FAT1 Tumor Suppressor Promotes Resistance to CDK4/6 Inhibitors via the Hippo Pathway.
    Li Z; Razavi P; Li Q; Toy W; Liu B; Ping C; Hsieh W; Sanchez-Vega F; Brown DN; Da Cruz Paula AF; Morris L; Selenica P; Eichenberger E; Shen R; Schultz N; Rosen N; Scaltriti M; Brogi E; Baselga J; Reis-Filho JS; Chandarlapaty S
    Cancer Cell; 2018 Dec; 34(6):893-905.e8. PubMed ID: 30537512
    [TBL] [Abstract][Full Text] [Related]  

  • 5. CDK4/6 Inhibitors Impede Chemoresistance and Inhibit Tumor Growth of Small Cell Lung Cancer.
    Wen Y; Sun X; Zeng L; Liang S; Li D; Chen X; Zeng F; Zhang C; Wang Q; Zhong Q; Deng L; Guo L
    Adv Sci (Weinh); 2024 Oct; 11(38):e2400666. PubMed ID: 39136283
    [TBL] [Abstract][Full Text] [Related]  

  • 6. CDK4/6 Inhibitor PD 0332991 Sensitizes Acute Myeloid Leukemia to Cytarabine-Mediated Cytotoxicity.
    Yang C; Boyson CA; Di Liberto M; Huang X; Hannah J; Dorn DC; Moore MA; Chen-Kiang S; Zhou P
    Cancer Res; 2015 May; 75(9):1838-45. PubMed ID: 25744718
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Functional Determinants of Cell Cycle Plasticity and Sensitivity to CDK4/6 Inhibition.
    Kumarasamy V; Vail P; Nambiar R; Witkiewicz AK; Knudsen ES
    Cancer Res; 2021 Mar; 81(5):1347-1360. PubMed ID: 33323381
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Targeting CDK4 and CDK6: From Discovery to Therapy.
    Sherr CJ; Beach D; Shapiro GI
    Cancer Discov; 2016 Apr; 6(4):353-67. PubMed ID: 26658964
    [TBL] [Abstract][Full Text] [Related]  

  • 9. DNA damage induced by CDK4 and CDK6 blockade triggers anti-tumor immune responses through cGAS-STING pathway.
    Fan H; Liu W; Zeng Y; Zhou Y; Gao M; Yang L; Liu H; Shi Y; Li L; Ma J; Ruan J; Cao R; Jin X; Chen J; Cheng G; Yang H
    Commun Biol; 2023 Oct; 6(1):1041. PubMed ID: 37833461
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A CDK4/6-Dependent Epigenetic Mechanism Protects Cancer Cells from PML-induced Senescence.
    Acevedo M; Vernier M; Mignacca L; Lessard F; Huot G; Moiseeva O; Bourdeau V; Ferbeyre G
    Cancer Res; 2016 Jun; 76(11):3252-64. PubMed ID: 27206849
    [TBL] [Abstract][Full Text] [Related]  

  • 11. SPH3643: A novel cyclin-dependent kinase 4/6 inhibitor with good anticancer efficacy and strong blood-brain barrier permeability.
    Liao X; Hong Y; Mao Y; Chen N; Wang Q; Wang Z; Zhang L; Wang L; Shi C; Shi W; Ge H; Li A; Li X; Xia G; Liu Y
    Cancer Sci; 2020 May; 111(5):1761-1773. PubMed ID: 32103527
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Nuclear factor of activated T cells c1 mediates p21-activated kinase 1 activation in the modulation of chemokine-induced human aortic smooth muscle cell F-actin stress fiber formation, migration, and proliferation and injury-induced vascular wall remodeling.
    Kundumani-Sridharan V; Singh NK; Kumar S; Gadepalli R; Rao GN
    J Biol Chem; 2013 Jul; 288(30):22150-62. PubMed ID: 23737530
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Kaempferol suppresses proliferation and induces apoptosis and DNA damage in human gallbladder cancer cells through the CDK4/CDK6/cyclin D1 pathway.
    Liu ZQ; Yao GL; Zhai JM; Hu DW; Fan YG
    Eur Rev Med Pharmacol Sci; 2021 Feb; 25(3):1311-1321. PubMed ID: 33629301
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Differential regulation of cyclin-dependent kinase 4 (CDK4) and CDK6, evidence that CDK4 might not be activated by CDK7, and design of a CDK6 activating mutation.
    Bockstaele L; Bisteau X; Paternot S; Roger PP
    Mol Cell Biol; 2009 Aug; 29(15):4188-200. PubMed ID: 19487459
    [TBL] [Abstract][Full Text] [Related]  

  • 15. CDK6-PI3K signaling axis is an efficient target for attenuating ABCB1/P-gp mediated multi-drug resistance (MDR) in cancer cells.
    Zhang L; Li Y; Hu C; Chen Y; Chen Z; Chen ZS; Zhang JY; Fang S
    Mol Cancer; 2022 Apr; 21(1):103. PubMed ID: 35459184
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The metabolic function of cyclin D3-CDK6 kinase in cancer cell survival.
    Wang H; Nicolay BN; Chick JM; Gao X; Geng Y; Ren H; Gao H; Yang G; Williams JA; Suski JM; Keibler MA; Sicinska E; Gerdemann U; Haining WN; Roberts TM; Polyak K; Gygi SP; Dyson NJ; Sicinski P
    Nature; 2017 Jun; 546(7658):426-430. PubMed ID: 28607489
    [TBL] [Abstract][Full Text] [Related]  

  • 17. CDK4/6-dependent activation of DUB3 regulates cancer metastasis through SNAIL1.
    Liu T; Yu J; Deng M; Yin Y; Zhang H; Luo K; Qin B; Li Y; Wu C; Ren T; Han Y; Yin P; Kim J; Lee S; Lin J; Zhang L; Zhang J; Nowsheen S; Wang L; Boughey J; Goetz MP; Yuan J; Lou Z
    Nat Commun; 2017 Jan; 8():13923. PubMed ID: 28067227
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Functional Genomic Analysis of CDK4 and CDK6 Gene Dependency across Human Cancer Cell Lines.
    Zhang Z; Golomb L; Meyerson M
    Cancer Res; 2022 Jun; 82(11):2171-2184. PubMed ID: 35395071
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Targeting Aberrant FGFR Signaling to Overcome CDK4/6 Inhibitor Resistance in Breast Cancer.
    Sobhani N; Fassl A; Mondani G; Generali D; Otto T
    Cells; 2021 Feb; 10(2):. PubMed ID: 33535617
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Attenuation of the retinoblastoma pathway in pancreatic neuroendocrine tumors due to increased cdk4/cdk6.
    Tang LH; Contractor T; Clausen R; Klimstra DS; Du YC; Allen PJ; Brennan MF; Levine AJ; Harris CR
    Clin Cancer Res; 2012 Sep; 18(17):4612-20. PubMed ID: 22761470
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.