These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

155 related articles for article (PubMed ID: 33395287)

  • 1. Antitubercular 2-Pyrazolylpyrimidinones: Structure-Activity Relationship and Mode-of-Action Studies.
    Soares de Melo C; Singh V; Myrick A; Simelane SB; Taylor D; Brunschwig C; Lawrence N; Schnappinger D; Engelhart CA; Kumar A; Parish T; Su Q; Myers TG; Boshoff HIM; Barry CE; Sirgel FA; van Helden PD; Buchanan KI; Bayliss T; Green SR; Ray PC; Wyatt PG; Basarab GS; Eyermann CJ; Chibale K; Ghorpade SR
    J Med Chem; 2021 Jan; 64(1):719-740. PubMed ID: 33395287
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Identification of New MmpL3 Inhibitors by Untargeted and Targeted Mutant Screens Defines MmpL3 Domains with Differential Resistance.
    Williams JT; Haiderer ER; Coulson GB; Conner KN; Ellsworth E; Chen C; Alvarez-Cabrera N; Li W; Jackson M; Dick T; Abramovitch RB
    Antimicrob Agents Chemother; 2019 Oct; 63(10):. PubMed ID: 31405862
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Aminopyrazolo[1,5-a]pyrimidines as potential inhibitors of Mycobacterium tuberculosis: Structure activity relationships and ADME characterization.
    Soares de Melo C; Feng TS; van der Westhuyzen R; Gessner RK; Street LJ; Morgans GL; Warner DF; Moosa A; Naran K; Lawrence N; Boshoff HI; Barry CE; Harris CJ; Gordon R; Chibale K
    Bioorg Med Chem; 2015 Nov; 23(22):7240-50. PubMed ID: 26522089
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A piperidinol-containing molecule is active against
    Dupont C; Chen Y; Xu Z; Roquet-Banères F; Blaise M; Witt AK; Dubar F; Biot C; Guérardel Y; Maurer FP; Chng SS; Kremer L
    J Biol Chem; 2019 Nov; 294(46):17512-17523. PubMed ID: 31562241
    [No Abstract]   [Full Text] [Related]  

  • 5. 1,3-Diarylpyrazolyl-acylsulfonamides as Potent Anti-tuberculosis Agents Targeting Cell Wall Biosynthesis in
    Khonde LP; Müller R; Boyle GA; Reddy V; Nchinda AT; Eyermann CJ; Fienberg S; Singh V; Myrick A; Abay E; Njoroge M; Lawrence N; Su Q; Myers TG; Boshoff HIM; Barry CE; Sirgel FA; van Helden PD; Massoudi LM; Robertson GT; Lenaerts AJ; Basarab GS; Ghorpade SR; Chibale K
    J Med Chem; 2021 Sep; 64(17):12790-12807. PubMed ID: 34414766
    [TBL] [Abstract][Full Text] [Related]  

  • 6. 1
    Korycka-Machała M; Viljoen A; Pawełczyk J; Borówka P; Dziadek B; Gobis K; Brzostek A; Kawka M; Blaise M; Strapagiel D; Kremer L; Dziadek J
    Antimicrob Agents Chemother; 2019 Oct; 63(10):. PubMed ID: 31332069
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Development of ssDNA aptamers as potent inhibitors of Mycobacterium tuberculosis acetohydroxyacid synthase.
    Baig IA; Moon JY; Lee SC; Ryoo SW; Yoon MY
    Biochim Biophys Acta; 2015 Oct; 1854(10 Pt A):1338-50. PubMed ID: 25988243
    [TBL] [Abstract][Full Text] [Related]  

  • 8. In silico Design and Synthesis of Tetrahydropyrimidinones and Tetrahydropyrimidinethiones as Potential Thymidylate Kinase Inhibitors Exerting Anti-TB Activity Against
    Venugopala KN; Tratrat C; Pillay M; Chandrashekharappa S; Al-Attraqchi OHA; Aldhubiab BE; Attimarad M; Alwassil OI; Nair AB; Sreeharsha N; Venugopala R; Morsy MA; Haroun M; Kumalo HM; Odhav B; Mlisana K
    Drug Des Devel Ther; 2020; 14():1027-1039. PubMed ID: 32214795
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Discovery of pyrazolopyridones as a novel class of noncovalent DprE1 inhibitor with potent anti-mycobacterial activity.
    Panda M; Ramachandran S; Ramachandran V; Shirude PS; Humnabadkar V; Nagalapur K; Sharma S; Kaur P; Guptha S; Narayan A; Mahadevaswamy J; Ambady A; Hegde N; Rudrapatna SS; Hosagrahara VP; Sambandamurthy VK; Raichurkar A
    J Med Chem; 2014 Jun; 57(11):4761-71. PubMed ID: 24818517
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Novel Antitubercular 6-Dialkylaminopyrimidine Carboxamides from Phenotypic Whole-Cell High Throughput Screening of a SoftFocus Library: Structure-Activity Relationship and Target Identification Studies.
    Wilson CR; Gessner RK; Moosa A; Seldon R; Warner DF; Mizrahi V; Soares de Melo C; Simelane SB; Nchinda A; Abay E; Taylor D; Njoroge M; Brunschwig C; Lawrence N; Boshoff HIM; Barry CE; Sirgel FA; van Helden P; Harris CJ; Gordon R; Ghidelli-Disse S; Pflaumer H; Boesche M; Drewes G; Sanz O; Santos G; Rebollo-Lopez MJ; Urones B; Selenski C; Lafuente-Monasterio MJ; Axtman M; Lelièvre J; Ballell L; Mueller R; Street LJ; Ghorpade SR; Chibale K
    J Med Chem; 2017 Dec; 60(24):10118-10134. PubMed ID: 29148755
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Active Benzimidazole Derivatives Targeting the MmpL3 Transporter in
    Raynaud C; Daher W; Johansen MD; Roquet-Banères F; Blaise M; Onajole OK; Kozikowski AP; Herrmann JL; Dziadek J; Gobis K; Kremer L
    ACS Infect Dis; 2020 Feb; 6(2):324-337. PubMed ID: 31860799
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Discovery and Structure-Activity-Relationship Study of N-Alkyl-5-hydroxypyrimidinone Carboxamides as Novel Antitubercular Agents Targeting Decaprenylphosphoryl-β-d-ribose 2'-Oxidase.
    Oh S; Park Y; Engelhart CA; Wallach JB; Schnappinger D; Arora K; Manikkam M; Gac B; Wang H; Murgolo N; Olsen DB; Goodwin M; Sutphin M; Weiner DM; Via LE; Boshoff HIM; Barry CE
    J Med Chem; 2018 Nov; 61(22):9952-9965. PubMed ID: 30350998
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Novel chemical entities inhibiting Mycobacterium tuberculosis growth identified by phenotypic high-throughput screening.
    Kumar A; Chettiar S; Brown BS; Early J; Ollinger J; Files M; Bailey MA; Korkegian A; Dennison D; McNeil M; Metz J; Osuma A; Curtin M; Kunzer A; Freiberg G; Bruncko M; Kempf D; Parish T
    Sci Rep; 2022 Sep; 12(1):14879. PubMed ID: 36050506
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide and N-benzyl-6',7'-dihydrospiro[piperidine-4,4'-thieno[3,2-c]pyran] analogues with bactericidal efficacy against Mycobacterium tuberculosis targeting MmpL3.
    Remuiñán MJ; Pérez-Herrán E; Rullás J; Alemparte C; Martínez-Hoyos M; Dow DJ; Afari J; Mehta N; Esquivias J; Jiménez E; Ortega-Muro F; Fraile-Gabaldón MT; Spivey VL; Loman NJ; Pallen MJ; Constantinidou C; Minick DJ; Cacho M; Rebollo-López MJ; González C; Sousa V; Angulo-Barturen I; Mendoza-Losana A; Barros D; Besra GS; Ballell L; Cammack N
    PLoS One; 2013; 8(4):e60933. PubMed ID: 23613759
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Multiple Mutations in Mycobacterium tuberculosis MmpL3 Increase Resistance to MmpL3 Inhibitors.
    McNeil MB; O'Malley T; Dennison D; Shelton CD; Sunde B; Parish T
    mSphere; 2020 Oct; 5(5):. PubMed ID: 33055263
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Identification of a novel inhibitor of isocitrate lyase as a potent antitubercular agent against both active and non-replicating Mycobacterium tuberculosis.
    Liu Y; Zhou S; Deng Q; Li X; Meng J; Guan Y; Li C; Xiao C
    Tuberculosis (Edinb); 2016 Mar; 97():38-46. PubMed ID: 26980494
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Development of gallic acid formazans as novel enoyl acyl carrier protein reductase inhibitors for the treatment of tuberculosis.
    Saharan VD; Mahajan SS
    Bioorg Med Chem Lett; 2017 Feb; 27(4):808-815. PubMed ID: 28117201
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Diphenylether-Modified 1,2-Diamines with Improved Drug Properties for Development against Mycobacterium tuberculosis.
    Foss MH; Pou S; Davidson PM; Dunaj JL; Winter RW; Pou S; Licon MH; Doh JK; Li Y; Kelly JX; Dodean RA; Koop DR; Riscoe MK; Purdy GE
    ACS Infect Dis; 2016 Jul; 2(7):500-8. PubMed ID: 27626102
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The antitubercular activity of various nitro(triazole/imidazole)-based compounds.
    Papadopoulou MV; Bloomer WD; Rosenzweig HS
    Bioorg Med Chem; 2017 Nov; 25(21):6039-6048. PubMed ID: 28993106
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Design, synthesis and antimycobacterial evaluation of novel adamantane and adamantanol analogues effective against drug-resistant tuberculosis.
    Alsayed SSR; Lun S; Payne A; Bishai WR; Gunosewoyo H
    Bioorg Chem; 2021 Jan; 106():104486. PubMed ID: 33276981
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.