BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

227 related articles for article (PubMed ID: 33398329)

  • 1. mTORC1 promotes TOP mRNA translation through site-specific phosphorylation of LARP1.
    Jia JJ; Lahr RM; Solgaard MT; Moraes BJ; Pointet R; Yang AD; Celucci G; Graber TE; Hoang HD; Niklaus MR; Pena IA; Hollensen AK; Smith EM; Chaker-Margot M; Anton L; Dajadian C; Livingstone M; Hearnden J; Wang XD; Yu Y; Maier T; Damgaard CK; Berman AJ; Alain T; Fonseca BD
    Nucleic Acids Res; 2021 Apr; 49(6):3461-3489. PubMed ID: 33398329
    [TBL] [Abstract][Full Text] [Related]  

  • 2. La-related Protein 1 (LARP1) Represses Terminal Oligopyrimidine (TOP) mRNA Translation Downstream of mTOR Complex 1 (mTORC1).
    Fonseca BD; Zakaria C; Jia JJ; Graber TE; Svitkin Y; Tahmasebi S; Healy D; Hoang HD; Jensen JM; Diao IT; Lussier A; Dajadian C; Padmanabhan N; Wang W; Matta-Camacho E; Hearnden J; Smith EM; Tsukumo Y; Yanagiya A; Morita M; Petroulakis E; González JL; Hernández G; Alain T; Damgaard CK
    J Biol Chem; 2015 Jun; 290(26):15996-6020. PubMed ID: 25940091
    [TBL] [Abstract][Full Text] [Related]  

  • 3. La-related protein 1 (LARP1) repression of TOP mRNA translation is mediated through its cap-binding domain and controlled by an adjacent regulatory region.
    Philippe L; Vasseur JJ; Debart F; Thoreen CC
    Nucleic Acids Res; 2018 Feb; 46(3):1457-1469. PubMed ID: 29244122
    [TBL] [Abstract][Full Text] [Related]  

  • 4. La-related protein 1 (LARP1) binds the mRNA cap, blocking eIF4F assembly on TOP mRNAs.
    Lahr RM; Fonseca BD; Ciotti GE; Al-Ashtal HA; Jia JJ; Niklaus MR; Blagden SP; Alain T; Berman AJ
    Elife; 2017 Apr; 6():. PubMed ID: 28379136
    [TBL] [Abstract][Full Text] [Related]  

  • 5. LARP1 functions as a molecular switch for mTORC1-mediated translation of an essential class of mRNAs.
    Hong S; Freeberg MA; Han T; Kamath A; Yao Y; Fukuda T; Suzuki T; Kim JK; Inoki K
    Elife; 2017 Jun; 6():. PubMed ID: 28650797
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Proteomic analysis of cap-dependent translation identifies LARP1 as a key regulator of 5'TOP mRNA translation.
    Tcherkezian J; Cargnello M; Romeo Y; Huttlin EL; Lavoie G; Gygi SP; Roux PP
    Genes Dev; 2014 Feb; 28(4):357-71. PubMed ID: 24532714
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The LARP1 La-Module recognizes both ends of TOP mRNAs.
    Al-Ashtal HA; Rubottom CM; Leeper TC; Berman AJ
    RNA Biol; 2021 Feb; 18(2):248-258. PubMed ID: 31601159
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Capturing the Mechanism Underlying TOP mRNA Binding to LARP1.
    Cassidy KC; Lahr RM; Kaminsky JC; Mack S; Fonseca BD; Das SR; Berman AJ; Durrant JD
    Structure; 2019 Dec; 27(12):1771-1781.e5. PubMed ID: 31676287
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Global analysis of LARP1 translation targets reveals tunable and dynamic features of 5' TOP motifs.
    Philippe L; van den Elzen AMG; Watson MJ; Thoreen CC
    Proc Natl Acad Sci U S A; 2020 Mar; 117(10):5319-5328. PubMed ID: 32094190
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The amino acid sensor GCN2 suppresses terminal oligopyrimidine (TOP) mRNA translation via La-related protein 1 (LARP1).
    Farooq Z; Kusuma F; Burke P; Dufour CR; Lee D; Tabatabaei N; Toboz P; Radovani E; Greenblatt JF; Rehman J; Class J; Khoutorsky A; Fonseca BD; Richner JM; Mercier E; Bourque G; Giguère V; Subramaniam AR; Han J; Tahmasebi S
    J Biol Chem; 2022 Sep; 298(9):102277. PubMed ID: 35863436
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Distinct roles of LARP1 and 4EBP1/2 in regulating translation and stability of 5'TOP mRNAs.
    Hochstoeger T; Papasaikas P; Piskadlo E; Chao JA
    Sci Adv; 2024 Feb; 10(7):eadi7830. PubMed ID: 38363833
    [TBL] [Abstract][Full Text] [Related]  

  • 12. LARP1 and LARP4: up close with PABP for mRNA 3' poly(A) protection and stabilization.
    Mattijssen S; Kozlov G; Fonseca BD; Gehring K; Maraia RJ
    RNA Biol; 2021 Feb; 18(2):259-274. PubMed ID: 33522422
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The LARP1 homolog Slr1p controls the stability and expression of proto-5'TOP mRNAs in fission yeast.
    Mansouri-Noori F; Pircher A; Bilodeau D; Siniavskaia L; Grigull J; Rissland OS; Bayfield MA
    Cell Rep; 2023 Oct; 42(10):113226. PubMed ID: 37851576
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The isolated La-module of LARP1 mediates 3' poly(A) protection and mRNA stabilization, dependent on its intrinsic PAM2 binding to PABPC1.
    Mattijssen S; Kozlov G; Gaidamakov S; Ranjan A; Fonseca BD; Gehring K; Maraia RJ
    RNA Biol; 2021 Feb; 18(2):275-289. PubMed ID: 33292040
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The La-related protein 1-specific domain repurposes HEAT-like repeats to directly bind a 5'TOP sequence.
    Lahr RM; Mack SM; Héroux A; Blagden SP; Bousquet-Antonelli C; Deragon JM; Berman AJ
    Nucleic Acids Res; 2015 Sep; 43(16):8077-88. PubMed ID: 26206669
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A unifying model for mTORC1-mediated regulation of mRNA translation.
    Thoreen CC; Chantranupong L; Keys HR; Wang T; Gray NS; Sabatini DM
    Nature; 2012 May; 485(7396):109-13. PubMed ID: 22552098
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The RNA-binding protein LARP1 is dispensable for pancreatic β-cell function and mass.
    Werneck-de-Castro JP; Peçanha FLM; Silvestre DH; Bernal-Mizrachi E
    Sci Rep; 2021 Jan; 11(1):2079. PubMed ID: 33483593
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Controversies around the function of LARP1.
    Berman AJ; Thoreen CC; Dedeic Z; Chettle J; Roux PP; Blagden SP
    RNA Biol; 2021 Feb; 18(2):207-217. PubMed ID: 32233986
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The mTOR regulated RNA-binding protein LARP1 requires PABPC1 for guided mRNA interaction.
    Smith EM; Benbahouche NEH; Morris K; Wilczynska A; Gillen S; Schmidt T; Meijer HA; Jukes-Jones R; Cain K; Jones C; Stoneley M; Waldron JA; Bell C; Fonseca BD; Blagden S; Willis AE; Bushell M
    Nucleic Acids Res; 2021 Jan; 49(1):458-478. PubMed ID: 33332560
    [TBL] [Abstract][Full Text] [Related]  

  • 20. An unusual mode of baseline translation adjusts cellular protein synthesis capacity to metabolic needs.
    Schneider C; Erhard F; Binotti B; Buchberger A; Vogel J; Fischer U
    Cell Rep; 2022 Oct; 41(2):111467. PubMed ID: 36223745
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.