BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

269 related articles for article (PubMed ID: 33400855)

  • 1. Reprogramming of aerobic glycolysis in non-transformed mouse liver with pyruvate dehydrogenase complex deficiency.
    Patel MS; Mahmood S; Jung J; Rideout TC
    Physiol Rep; 2021 Jan; 9(1):e14684. PubMed ID: 33400855
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Lack of mitochondria-generated acetyl-CoA by pyruvate dehydrogenase complex downregulates gene expression in the hepatic de novo lipogenic pathway.
    Mahmood S; Birkaya B; Rideout TC; Patel MS
    Am J Physiol Endocrinol Metab; 2016 Jul; 311(1):E117-27. PubMed ID: 27166281
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Therapeutic potential of the mammalian pyruvate dehydrogenase kinases in the prevention of hyperglycaemia.
    Sugden MC; Holness MJ
    Curr Drug Targets Immune Endocr Metabol Disord; 2002 Jul; 2(2):151-65. PubMed ID: 12476789
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The cellular and compartmental profile of mouse retinal glycolysis, tricarboxylic acid cycle, oxidative phosphorylation, and ~P transferring kinases.
    Rueda EM; Johnson JE; Giddabasappa A; Swaroop A; Brooks MJ; Sigel I; Chaney SY; Fox DA
    Mol Vis; 2016; 22():847-85. PubMed ID: 27499608
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Therapeutic Targeting of the Pyruvate Dehydrogenase Complex/Pyruvate Dehydrogenase Kinase (PDC/PDK) Axis in Cancer.
    Stacpoole PW
    J Natl Cancer Inst; 2017 Nov; 109(11):. PubMed ID: 29059435
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Liver-specific pyruvate dehydrogenase complex deficiency upregulates lipogenesis in adipose tissue and improves peripheral insulin sensitivity.
    Choi CS; Ghoshal P; Srinivasan M; Kim S; Cline G; Patel MS
    Lipids; 2010 Nov; 45(11):987-95. PubMed ID: 20835892
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Anti-Warburg Effect of Melatonin: A Proposed Mechanism to Explain its Inhibition of Multiple Diseases.
    Reiter RJ; Sharma R; Rosales-Corral S
    Int J Mol Sci; 2021 Jan; 22(2):. PubMed ID: 33466614
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Lactic acidosis caused by repressed lactate dehydrogenase subunit B expression down-regulates mitochondrial oxidative phosphorylation via the pyruvate dehydrogenase (PDH)-PDH kinase axis.
    Hong SM; Lee YK; Park I; Kwon SM; Min S; Yoon G
    J Biol Chem; 2019 May; 294(19):7810-7820. PubMed ID: 30923124
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Acetyl-CoA production from pyruvate is not necessary for preservation of myelin.
    Della-Flora Nunes G; Mueller L; Silvestri N; Patel MS; Wrabetz L; Feltri ML; Poitelon Y
    Glia; 2017 Oct; 65(10):1626-1639. PubMed ID: 28657129
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The pyruvate carboxylase-pyruvate dehydrogenase axis in islet pyruvate metabolism: Going round in circles?
    Sugden MC; Holness MJ
    Islets; 2011; 3(6):302-19. PubMed ID: 21934355
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Revisited Metabolic Control and Reprogramming Cancers by Means of the Warburg Effect in Tumor Cells.
    Fukushi A; Kim HD; Chang YC; Kim CH
    Int J Mol Sci; 2022 Sep; 23(17):. PubMed ID: 36077431
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Pyruvate dehydrogenase complex activity in normal and deficient fibroblasts.
    Sheu KF; Hu CW; Utter MF
    J Clin Invest; 1981 May; 67(5):1463-71. PubMed ID: 6262377
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The pyruvate dehydrogenase complex: Life's essential, vulnerable and druggable energy homeostat.
    Stacpoole PW; McCall CE
    Mitochondrion; 2023 May; 70():59-102. PubMed ID: 36863425
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Magnetic resonance spectroscopic investigation of mitochondrial fuel metabolism and energetics in cultured human fibroblasts: effects of pyruvate dehydrogenase complex deficiency and dichloroacetate.
    Simpson NE; Han Z; Berendzen KM; Sweeney CA; Oca-Cossio JA; Constantinidis I; Stacpoole PW
    Mol Genet Metab; 2006; 89(1-2):97-105. PubMed ID: 16765624
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Pyruvate dehydrogenase deficiency: morphological and metabolic effects, creation of animal model to search for curative treatment.
    Ebertowska A; Ludkiewicz B; Klejbor I; Melka N; Moryś J
    Folia Morphol (Warsz); 2020; 79(2):191-197. PubMed ID: 32073132
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Microenvironmental control of glucose metabolism in tumors by regulation of pyruvate dehydrogenase.
    Golias T; Kery M; Radenkovic S; Papandreou I
    Int J Cancer; 2019 Feb; 144(4):674-686. PubMed ID: 30121950
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Control of cardiac pyruvate dehydrogenase activity in peroxisome proliferator-activated receptor-alpha transgenic mice.
    Hopkins TA; Sugden MC; Holness MJ; Kozak R; Dyck JR; Lopaschuk GD
    Am J Physiol Heart Circ Physiol; 2003 Jul; 285(1):H270-6. PubMed ID: 12663261
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Targeting pyruvate dehydrogenase kinase signaling in the development of effective cancer therapy.
    Anwar S; Shamsi A; Mohammad T; Islam A; Hassan MI
    Biochim Biophys Acta Rev Cancer; 2021 Aug; 1876(1):188568. PubMed ID: 34023419
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Structural and functional impact of clinically relevant E1α variants causing pyruvate dehydrogenase complex deficiency.
    Pavlu-Pereira H; Lousa D; Tomé CS; Florindo C; Silva MJ; de Almeida IT; Leandro P; Rivera I; Vicente JB
    Biochimie; 2021 Apr; 183():78-88. PubMed ID: 33588022
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Pyruvate dehydrogenase complex deficiency is linked to regulatory loop disorder in the αV138M variant of human pyruvate dehydrogenase.
    Whitley MJ; Arjunan P; Nemeria NS; Korotchkina LG; Park YH; Patel MS; Jordan F; Furey W
    J Biol Chem; 2018 Aug; 293(34):13204-13213. PubMed ID: 29970614
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.