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5. TSC2 S1365A mutation potently regulates CD8+ T cell function and differentiation and improves adoptive cellular cancer therapy. Patel CH; Dong Y; Koleini N; Wang X; Dunkerly-Eyring BL; Wen J; Ranek MJ; Bartle LM; Henderson DB; Sagert J; Kass DA; Powell JD JCI Insight; 2023 Nov; 8(21):. PubMed ID: 37788104 [TBL] [Abstract][Full Text] [Related]
6. Interleukin-6 mediates PSAT1 expression and serine metabolism in TSC2-deficient cells. Wang J; Filippakis H; Hougard T; Du H; Ye C; Liu HJ; Zhang L; Hindi K; Bagwe S; Nijmeh J; Asara JM; Shi W; El-Chemaly S; Henske EP; Lam HC Proc Natl Acad Sci U S A; 2021 Sep; 118(39):. PubMed ID: 34544857 [TBL] [Abstract][Full Text] [Related]
7. Pre-ischaemic mitochondrial substrate constraint by inhibition of malate-aspartate shuttle preserves mitochondrial function after ischaemia-reperfusion. Jespersen NR; Yokota T; Støttrup NB; Bergdahl A; Paelestik KB; Povlsen JA; Dela F; Bøtker HE J Physiol; 2017 Jun; 595(12):3765-3780. PubMed ID: 28093764 [TBL] [Abstract][Full Text] [Related]
8. Phosphorylation of TSC2 by PKC-δ reveals a novel signaling pathway that couples protein synthesis to mTORC1 activity. Zhan J; Chitta RK; Harwood FC; Grosveld GC Mol Cell Biochem; 2019 Jun; 456(1-2):123-134. PubMed ID: 30684133 [TBL] [Abstract][Full Text] [Related]
9. Inhibition of the malate-aspartate shuttle by pre-ischaemic aminooxyacetate loading of the heart induces cardioprotection. Støttrup NB; Løfgren B; Birkler RD; Nielsen JM; Wang L; Caldarone CA; Kristiansen SB; Contractor H; Johannsen M; Bøtker HE; Nielsen TT Cardiovasc Res; 2010 Nov; 88(2):257-66. PubMed ID: 20562422 [TBL] [Abstract][Full Text] [Related]
10. Upregulation of 6-phosphofructo-2-kinase (PFKFB3) by hyperactivated mammalian target of rapamycin complex 1 is critical for tumor growth in tuberous sclerosis complex. Wang Y; Tang S; Wu Y; Wan X; Zhou M; Li H; Zha X IUBMB Life; 2020 May; 72(5):965-977. PubMed ID: 31958214 [TBL] [Abstract][Full Text] [Related]
11. Single serine on TSC2 exerts biased control over mTORC1 activation mediated by ERK1/2 but not Akt. Dunkerly-Eyring BL; Pan S; Pinilla-Vera M; McKoy D; Mishra S; Grajeda Martinez MI; Oeing CU; Ranek MJ; Kass DA Life Sci Alliance; 2022 Jun; 5(6):. PubMed ID: 35288456 [TBL] [Abstract][Full Text] [Related]
12. Cardioprotection via preserved mitochondrial structure and function in the mPer2-mutant mouse myocardium. Virag JA; Anderson EJ; Kent SD; Blanton HD; Johnson TL; Moukdar F; DeAntonio JH; Thayne K; Ding JM; Lust RM Am J Physiol Heart Circ Physiol; 2013 Aug; 305(4):H477-83. PubMed ID: 23771689 [TBL] [Abstract][Full Text] [Related]
13. Methionine controls insulin/mammalian target of rapamycin complex 1 activity by modulating tuberous sclerosis complex 2 stability. Gen S; Matsumoto Y; Suzuki T; Inoue J; Yamamoto Y Biochem Biophys Res Commun; 2021 Feb; 541():84-89. PubMed ID: 33482580 [TBL] [Abstract][Full Text] [Related]
14. Upregulation of C/EBPβ and TSC2 by an HDAC inhibitor CG200745 protects heart from DOCA-induced hypertrophy. Lee E; Lee HA; Kim M; Do GY; Cho HM; Kim GJ; Jung H; Song JH; Cho JM; Kim I Clin Exp Pharmacol Physiol; 2019 Mar; 46(3):226-236. PubMed ID: 30099761 [TBL] [Abstract][Full Text] [Related]
16. mTOR Hyperactivation by Ablation of Tuberous Sclerosis Complex 2 in the Mouse Heart Induces Cardiac Dysfunction with the Increased Number of Small Mitochondria Mediated through the Down-Regulation of Autophagy. Taneike M; Nishida K; Omiya S; Zarrinpashneh E; Misaka T; Kitazume-Taneike R; Austin R; Takaoka M; Yamaguchi O; Gambello MJ; Shah AM; Otsu K PLoS One; 2016; 11(3):e0152628. PubMed ID: 27023784 [TBL] [Abstract][Full Text] [Related]
17. TSC2 regulates microRNA biogenesis via mTORC1 and GSK3β. Ogórek B; Lam HC; Khabibullin D; Liu HJ; Nijmeh J; Triboulet R; Kwiatkowski DJ; Gregory RI; Henske EP Hum Mol Genet; 2018 May; 27(9):1654-1663. PubMed ID: 29509898 [TBL] [Abstract][Full Text] [Related]
18. HDAC6-G3BP2 promotes lysosomal-TSC2 and suppresses mTORC1 under ETV4 targeting-induced low-lactate stress in non-small cell lung cancer. Liu B; Zhang J; Meng X; Xie SM; Liu F; Chen H; Yao D; Li M; Guo M; Shen H; Zhang X; Xing L Oncogene; 2023 Apr; 42(15):1181-1195. PubMed ID: 36823378 [TBL] [Abstract][Full Text] [Related]
19. Reduced cardiac CapZ protein protects hearts against acute ischemia-reperfusion injury and enhances preconditioning. Yang FH; Pyle WG J Mol Cell Cardiol; 2012 Mar; 52(3):761-72. PubMed ID: 22155006 [TBL] [Abstract][Full Text] [Related]
20. Metabolomic profiling of the heart during acute ischemic preconditioning reveals a role for SIRT1 in rapid cardioprotective metabolic adaptation. Nadtochiy SM; Urciuoli W; Zhang J; Schafer X; Munger J; Brookes PS J Mol Cell Cardiol; 2015 Nov; 88():64-72. PubMed ID: 26388263 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]