161 related articles for article (PubMed ID: 33402044)
1. Development of a High-Throughput Assay to Identify Inhibitors of ENPP1.
Kumar M; Lowery RG
SLAS Discov; 2021 Jun; 26(5):740-746. PubMed ID: 33402044
[TBL] [Abstract][Full Text] [Related]
2. ENPP1, an Old Enzyme with New Functions, and Small Molecule Inhibitors-A STING in the Tale of ENPP1.
Onyedibe KI; Wang M; Sintim HO
Molecules; 2019 Nov; 24(22):. PubMed ID: 31752288
[TBL] [Abstract][Full Text] [Related]
3. Structural insights into cGAMP degradation by Ecto-nucleotide pyrophosphatase phosphodiesterase 1.
Kato K; Nishimasu H; Oikawa D; Hirano S; Hirano H; Kasuya G; Ishitani R; Tokunaga F; Nureki O
Nat Commun; 2018 Oct; 9(1):4424. PubMed ID: 30356045
[TBL] [Abstract][Full Text] [Related]
4. Tumor Exosomal ENPP1 Hydrolyzes cGAMP to Inhibit cGAS-STING Signaling.
An Y; Zhu J; Xie Q; Feng J; Gong Y; Fan Q; Cao J; Huang Z; Shi W; Lin Q; Wu L; Yang C; Ji T
Adv Sci (Weinh); 2024 May; 11(20):e2308131. PubMed ID: 38498770
[TBL] [Abstract][Full Text] [Related]
5. Maintenance of cyclic GMP-AMP homeostasis by ENPP1 is involved in pseudorabies virus infection.
Wang J; Lu SF; Wan B; Ming SL; Li GL; Su BQ; Liu JY; Wei YS; Yang GY; Chu BB
Mol Immunol; 2018 Mar; 95():56-63. PubMed ID: 29407577
[TBL] [Abstract][Full Text] [Related]
6. Crystal structures of human ENPP1 in apo and bound forms.
Dennis ML; Newman J; Dolezal O; Hattarki M; Surjadi RN; Nuttall SD; Pham T; Nebl T; Camerino M; Khoo PS; Monahan BJ; Peat TS
Acta Crystallogr D Struct Biol; 2020 Sep; 76(Pt 9):889-898. PubMed ID: 32876064
[TBL] [Abstract][Full Text] [Related]
7. Structure-Aided Development of Small-Molecule Inhibitors of ENPP1, the Extracellular Phosphodiesterase of the Immunotransmitter cGAMP.
Carozza JA; Brown JA; Böhnert V; Fernandez D; AlSaif Y; Mardjuki RE; Smith M; Li L
Cell Chem Biol; 2020 Nov; 27(11):1347-1358.e5. PubMed ID: 32726585
[TBL] [Abstract][Full Text] [Related]
8. ENPP1 is an innate immune checkpoint of the anticancer cGAMP-STING pathway in breast cancer.
Wang S; Böhnert V; Joseph AJ; Sudaryo V; Skariah G; Swinderman JT; Yu FB; Subramanyam V; Wolf DM; Lyu X; Gilbert LA; Van't Veer LJ; Goodarzi H; Li L
Proc Natl Acad Sci U S A; 2023 Dec; 120(52):e2313693120. PubMed ID: 38117852
[TBL] [Abstract][Full Text] [Related]
9. Identification of the extracellular membrane protein ENPP3 as a major cGAMP hydrolase and innate immune checkpoint.
Mardjuki R; Wang S; Carozza J; Zirak B; Subramanyam V; Abhiraman G; Lyu X; Goodarzi H; Li L
Cell Rep; 2024 May; 43(5):114209. PubMed ID: 38749434
[TBL] [Abstract][Full Text] [Related]
10. Development of cGAMP-Luc, a sensitive and precise coupled enzyme assay to measure cGAMP in complex biological samples.
Mardjuki RE; Carozza JA; Li L
J Biol Chem; 2020 Apr; 295(15):4881-4892. PubMed ID: 32127400
[TBL] [Abstract][Full Text] [Related]
11. Discovery of Orally Bioavailable Phthalazinone Analogues as an ENPP1 Inhibitor for STING-Mediated Cancer Immunotherapy.
Cho Y; Kang M; Ji SH; Jeong HJ; Jung JE; Oh DH; Park S; Park YY; Choi J; Kim S; Kim NJ; Lee DH; Park CS; Han SJ; Lee S; Choi J
J Med Chem; 2023 Nov; 66(22):15141-15170. PubMed ID: 37963811
[TBL] [Abstract][Full Text] [Related]
12. Development of Novel Ecto-Nucleotide Pyrophosphatase/Phosphodiesterase 1 (ENPP1) Inhibitors for Tumor Immunotherapy.
Wang X; Lu X; Yan D; Zhou Y; Tan X
Int J Mol Sci; 2022 Jun; 23(13):. PubMed ID: 35806118
[TBL] [Abstract][Full Text] [Related]
13. Insight into small-molecule inhibitors targeting extracellular nucleotide pyrophosphatase/phosphodiesterase1 for potential multiple human diseases.
Du B; Ru J; Zhan Z; Lin C; Liu Y; Mao W; Zhang J
Eur J Med Chem; 2024 Mar; 268():116286. PubMed ID: 38432057
[TBL] [Abstract][Full Text] [Related]
14. Ecto-nucleotide pyrophosphatase/phosphodiesterase 1 inhibitors: Research progress and prospects.
Guan D; Fang L; Feng M; Guo S; Xie L; Chen C; Sun X; Wu Q; Yuan X; Xie Z; Zhou J; Zhang H
Eur J Med Chem; 2024 Mar; 267():116211. PubMed ID: 38359537
[TBL] [Abstract][Full Text] [Related]
15. New activity assays for ENPP1 with physiological substrates ATP and ADP.
Ma CT; Sergienko EA
Methods Mol Biol; 2013; 1053():145-54. PubMed ID: 23860653
[TBL] [Abstract][Full Text] [Related]
16. AVA-NP-695 Selectively Inhibits ENPP1 to Activate STING Pathway and Abrogate Tumor Metastasis in 4T1 Breast Cancer Syngeneic Mouse Model.
Goswami A; Deb B; Goyal S; Gosavi A; Mali M; Martis AM; Khurana P; Gangar M; Raykar D; Mohanty A; Kulkarni A
Molecules; 2022 Oct; 27(19):. PubMed ID: 36235254
[TBL] [Abstract][Full Text] [Related]
17. Development and validation of a transcreener assay for detection of AMP- and GMP-producing enzymes.
Staeben M; Kleman-Leyer KM; Kopp AL; Westermeyer TA; Lowery RG
Assay Drug Dev Technol; 2010 Jun; 8(3):344-55. PubMed ID: 20158441
[TBL] [Abstract][Full Text] [Related]
18. Development of an ENPP1 Fluorescence Probe for Inhibitor Screening, Cellular Imaging, and Prognostic Assessment of Malignant Breast Cancer.
Kawaguchi M; Han X; Hisada T; Nishikawa S; Kano K; Ieda N; Aoki J; Toyama T; Nakagawa H
J Med Chem; 2019 Oct; 62(20):9254-9269. PubMed ID: 31536342
[TBL] [Abstract][Full Text] [Related]
19. Design, synthesis and biological evaluation studies of novel small molecule ENPP1 inhibitors for cancer immunotherapy.
Gangar M; Goyal S; Raykar D; Khurana P; Martis AM; Goswami A; Ghoshal I; Patel KV; Nagare Y; Raikar S; Mukherjee A; Cyriac R; Paquin JF; Kulkarni A
Bioorg Chem; 2022 Feb; 119():105549. PubMed ID: 34929517
[TBL] [Abstract][Full Text] [Related]
20. Targeting ENPP1 for cancer immunotherapy: Killing two birds with one stone.
Huang R; Ning Q; Zhao J; Zhao X; Zeng L; Yi Y; Tang S
Biochem Pharmacol; 2024 Feb; 220():116006. PubMed ID: 38142838
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
