246 related articles for article (PubMed ID: 33407930)
1. Dysfunction in nonsense-mediated decay, protein homeostasis, mitochondrial function, and brain connectivity in ALS-FUS mice with cognitive deficits.
Ho WY; Agrawal I; Tyan SH; Sanford E; Chang WT; Lim K; Ong J; Tan BSY; Moe AAK; Yu R; Wong P; Tucker-Kellogg G; Koo E; Chuang KH; Ling SC
Acta Neuropathol Commun; 2021 Jan; 9(1):9. PubMed ID: 33407930
[TBL] [Abstract][Full Text] [Related]
2. FUS-mediated dysregulation of Sema5a, an autism-related gene, in FUS mice with hippocampus-dependent cognitive deficits.
Ho WY; Chang JC; Tyan SH; Yen YC; Lim K; Tan BSY; Ong J; Tucker-Kellogg G; Wong P; Koo E; Ling SC
Hum Mol Genet; 2019 Nov; 28(22):3777-3791. PubMed ID: 31509188
[TBL] [Abstract][Full Text] [Related]
3. ALS mutations of FUS suppress protein translation and disrupt the regulation of nonsense-mediated decay.
Kamelgarn M; Chen J; Kuang L; Jin H; Kasarskis EJ; Zhu H
Proc Natl Acad Sci U S A; 2018 Dec; 115(51):E11904-E11913. PubMed ID: 30455313
[TBL] [Abstract][Full Text] [Related]
4. Neuronal dysfunction caused by FUSR521G promotes ALS-associated phenotypes that are attenuated by NF-κB inhibition.
Pelaez MC; Desmeules A; Gelon PA; Glasson B; Marcadet L; Rodgers A; Phaneuf D; Pozzi S; Dutchak PA; Julien JP; Sephton CF
Acta Neuropathol Commun; 2023 Nov; 11(1):182. PubMed ID: 37974279
[TBL] [Abstract][Full Text] [Related]
5. Expression of Fused in sarcoma mutations in mice recapitulates the neuropathology of FUS proteinopathies and provides insight into disease pathogenesis.
Verbeeck C; Deng Q; Dejesus-Hernandez M; Taylor G; Ceballos-Diaz C; Kocerha J; Golde T; Das P; Rademakers R; Dickson DW; Kukar T
Mol Neurodegener; 2012 Oct; 7():53. PubMed ID: 23046583
[TBL] [Abstract][Full Text] [Related]
6. Dendritic Homeostasis Disruption in a Novel Frontotemporal Dementia Mouse Model Expressing Cytoplasmic Fused in Sarcoma.
Shiihashi G; Ito D; Arai I; Kobayashi Y; Hayashi K; Otsuka S; Nakajima K; Yuzaki M; Itohara S; Suzuki N
EBioMedicine; 2017 Oct; 24():102-115. PubMed ID: 28928015
[TBL] [Abstract][Full Text] [Related]
7. ALS/FTD-Linked Mutation in FUS Suppresses Intra-axonal Protein Synthesis and Drives Disease Without Nuclear Loss-of-Function of FUS.
López-Erauskin J; Tadokoro T; Baughn MW; Myers B; McAlonis-Downes M; Chillon-Marinas C; Asiaban JN; Artates J; Bui AT; Vetto AP; Lee SK; Le AV; Sun Y; Jambeau M; Boubaker J; Swing D; Qiu J; Hicks GG; Ouyang Z; Fu XD; Tessarollo L; Ling SC; Parone PA; Shaw CE; Marsala M; Lagier-Tourenne C; Cleveland DW; Da Cruz S
Neuron; 2018 Nov; 100(4):816-830.e7. PubMed ID: 30344044
[TBL] [Abstract][Full Text] [Related]
8. Extensive splicing changes in an ALS/FTD transgenic mouse model overexpressing cytoplasmic fused in sarcoma.
Ito D; Taguchi R; Deguchi M; Ogasawara H; Inoue E
Sci Rep; 2020 Mar; 10(1):4857. PubMed ID: 32184412
[TBL] [Abstract][Full Text] [Related]
9. Pathogenesis of FUS-associated ALS and FTD: insights from rodent models.
Nolan M; Talbot K; Ansorge O
Acta Neuropathol Commun; 2016 Sep; 4(1):99. PubMed ID: 27600654
[TBL] [Abstract][Full Text] [Related]
10. Elevated FUS levels by overriding its autoregulation produce gain-of-toxicity properties that disrupt protein and RNA homeostasis.
Ho WY; Ling SC
Autophagy; 2019 Sep; 15(9):1665-1667. PubMed ID: 31230528
[TBL] [Abstract][Full Text] [Related]
11. Antisense oligonucleotide silencing of FUS expression as a therapeutic approach in amyotrophic lateral sclerosis.
Korobeynikov VA; Lyashchenko AK; Blanco-Redondo B; Jafar-Nejad P; Shneider NA
Nat Med; 2022 Jan; 28(1):104-116. PubMed ID: 35075293
[TBL] [Abstract][Full Text] [Related]
12. ALS/FTD-associated FUS activates GSK-3β to disrupt the VAPB-PTPIP51 interaction and ER-mitochondria associations.
Stoica R; Paillusson S; Gomez-Suaga P; Mitchell JC; Lau DH; Gray EH; Sancho RM; Vizcay-Barrena G; De Vos KJ; Shaw CE; Hanger DP; Noble W; Miller CC
EMBO Rep; 2016 Sep; 17(9):1326-42. PubMed ID: 27418313
[TBL] [Abstract][Full Text] [Related]
13. ALS/FTD-associated protein FUS induces mitochondrial dysfunction by preferentially sequestering respiratory chain complex mRNAs.
Tsai YL; Coady TH; Lu L; Zheng D; Alland I; Tian B; Shneider NA; Manley JL
Genes Dev; 2020 Jun; 34(11-12):785-805. PubMed ID: 32381627
[TBL] [Abstract][Full Text] [Related]
14. Nuclear transport dysfunction: a common theme in amyotrophic lateral sclerosis and frontotemporal dementia.
Jovičić A; Paul JW; Gitler AD
J Neurochem; 2016 Aug; 138 Suppl 1():134-44. PubMed ID: 27087014
[TBL] [Abstract][Full Text] [Related]
15. Conformational change of RNA-helicase DHX30 by ALS/FTD-linked FUS induces mitochondrial dysfunction and cytosolic aggregates.
Hikiami R; Morimura T; Ayaki T; Tsukiyama T; Morimura N; Kusui M; Wada H; Minamiyama S; Shodai A; Asada-Utsugi M; Muramatsu SI; Ueki T; Takahashi R; Urushitani M
Sci Rep; 2022 Sep; 12(1):16030. PubMed ID: 36163369
[TBL] [Abstract][Full Text] [Related]
16. Comparative interactomics analysis of different ALS-associated proteins identifies converging molecular pathways.
Blokhuis AM; Koppers M; Groen EJN; van den Heuvel DMA; Dini Modigliani S; Anink JJ; Fumoto K; van Diggelen F; Snelting A; Sodaar P; Verheijen BM; Demmers JAA; Veldink JH; Aronica E; Bozzoni I; den Hertog J; van den Berg LH; Pasterkamp RJ
Acta Neuropathol; 2016 Aug; 132(2):175-196. PubMed ID: 27164932
[TBL] [Abstract][Full Text] [Related]
17. Oxr1 improves pathogenic cellular features of ALS-associated FUS and TDP-43 mutations.
Finelli MJ; Liu KX; Wu Y; Oliver PL; Davies KE
Hum Mol Genet; 2015 Jun; 24(12):3529-44. PubMed ID: 25792726
[TBL] [Abstract][Full Text] [Related]
18. The ALS-associated proteins FUS and TDP-43 function together to affect Drosophila locomotion and life span.
Wang JW; Brent JR; Tomlinson A; Shneider NA; McCabe BD
J Clin Invest; 2011 Oct; 121(10):4118-26. PubMed ID: 21881207
[TBL] [Abstract][Full Text] [Related]
19. Motor-Coordinative and Cognitive Dysfunction Caused by Mutant TDP-43 Could Be Reversed by Inhibiting Its Mitochondrial Localization.
Wang W; Arakawa H; Wang L; Okolo O; Siedlak SL; Jiang Y; Gao J; Xie F; Petersen RB; Wang X
Mol Ther; 2017 Jan; 25(1):127-139. PubMed ID: 28129109
[TBL] [Abstract][Full Text] [Related]
20. Identification of a novel interaction of FUS and syntaphilin may explain synaptic and mitochondrial abnormalities caused by ALS mutations.
Salam S; Tacconelli S; Smith BN; Mitchell JC; Glennon E; Nikolaou N; Houart C; Vance C
Sci Rep; 2021 Jun; 11(1):13613. PubMed ID: 34193962
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]