224 related articles for article (PubMed ID: 33408125)
1. TDP-43 mislocalization drives neurofilament changes in a novel model of TDP-43 proteinopathy.
Atkinson R; Leung J; Bender J; Kirkcaldie M; Vickers J; King A
Dis Model Mech; 2021 Jan; 14(2):. PubMed ID: 33408125
[TBL] [Abstract][Full Text] [Related]
2. Dysregulation of the ALS-associated gene TDP-43 leads to neuronal death and degeneration in mice.
Igaz LM; Kwong LK; Lee EB; Chen-Plotkin A; Swanson E; Unger T; Malunda J; Xu Y; Winton MJ; Trojanowski JQ; Lee VM
J Clin Invest; 2011 Feb; 121(2):726-38. PubMed ID: 21206091
[TBL] [Abstract][Full Text] [Related]
3. Targeting RACK1 to alleviate TDP-43 and FUS proteinopathy-mediated suppression of protein translation and neurodegeneration.
Zhao B; Cowan CM; Coutts JA; Christy DD; Saraph A; Hsueh SCC; Plotkin SS; Mackenzie IR; Kaplan JM; Cashman NR
Acta Neuropathol Commun; 2023 Dec; 11(1):200. PubMed ID: 38111057
[TBL] [Abstract][Full Text] [Related]
4. Withania somnifera Reverses Transactive Response DNA Binding Protein 43 Proteinopathy in a Mouse Model of Amyotrophic Lateral Sclerosis/Frontotemporal Lobar Degeneration.
Dutta K; Patel P; Rahimian R; Phaneuf D; Julien JP
Neurotherapeutics; 2017 Apr; 14(2):447-462. PubMed ID: 27928708
[TBL] [Abstract][Full Text] [Related]
5. Functional recovery in new mouse models of ALS/FTLD after clearance of pathological cytoplasmic TDP-43.
Walker AK; Spiller KJ; Ge G; Zheng A; Xu Y; Zhou M; Tripathy K; Kwong LK; Trojanowski JQ; Lee VM
Acta Neuropathol; 2015 Nov; 130(5):643-60. PubMed ID: 26197969
[TBL] [Abstract][Full Text] [Related]
6. A Drosophila model for TDP-43 proteinopathy.
Li Y; Ray P; Rao EJ; Shi C; Guo W; Chen X; Woodruff EA; Fushimi K; Wu JY
Proc Natl Acad Sci U S A; 2010 Feb; 107(7):3169-74. PubMed ID: 20133767
[TBL] [Abstract][Full Text] [Related]
7. Transcriptomic Changes Due to Cytoplasmic TDP-43 Expression Reveal Dysregulation of Histone Transcripts and Nuclear Chromatin.
Amlie-Wolf A; Ryvkin P; Tong R; Dragomir I; Suh E; Xu Y; Van Deerlin VM; Gregory BD; Kwong LK; Trojanowski JQ; Lee VM; Wang LS; Lee EB
PLoS One; 2015; 10(10):e0141836. PubMed ID: 26510133
[TBL] [Abstract][Full Text] [Related]
8. Conjoint pathologic cascades mediated by ALS/FTLD-U linked RNA-binding proteins TDP-43 and FUS.
Ito D; Suzuki N
Neurology; 2011 Oct; 77(17):1636-43. PubMed ID: 21956718
[TBL] [Abstract][Full Text] [Related]
9. The pathological phenotypes of human TDP-43 transgenic mouse models are independent of downregulation of mouse Tdp-43.
Xu YF; Prudencio M; Hubbard JM; Tong J; Whitelaw EC; Jansen-West K; Stetler C; Cao X; Song J; Zhang YJ
PLoS One; 2013; 8(7):e69864. PubMed ID: 23922830
[TBL] [Abstract][Full Text] [Related]
10. Differential Neurotoxicity Related to Tetracycline Transactivator and TDP-43 Expression in Conditional TDP-43 Mouse Model of Frontotemporal Lobar Degeneration.
Kukreja L; Shahidehpour R; Kim G; Keegan J; Sadleir KR; Russell T; Csernansky J; Mesulam M; Vassar RJ; Wang L; Dong H; Geula C
J Neurosci; 2018 Jul; 38(27):6045-6062. PubMed ID: 29807909
[TBL] [Abstract][Full Text] [Related]
11. Expression of mutant TDP-43 induces neuronal dysfunction in transgenic mice.
Xu YF; Zhang YJ; Lin WL; Cao X; Stetler C; Dickson DW; Lewis J; Petrucelli L
Mol Neurodegener; 2011 Oct; 6():73. PubMed ID: 22029574
[TBL] [Abstract][Full Text] [Related]
12. Mislocalization of Nup62 Contributes to TDP-43 Proteinopathy in ALS/FTLD.
Nag N; Tripathi T
ACS Chem Neurosci; 2022 Sep; 13(17):2544-2546. PubMed ID: 36001801
[TBL] [Abstract][Full Text] [Related]
13. RNA-binding deficient TDP-43 drives cognitive decline in a mouse model of TDP-43 proteinopathy.
Necarsulmer JC; Simon JM; Evangelista BA; Chen Y; Tian X; Nafees S; Marquez AB; Jiang H; Wang P; Ajit D; Nikolova VD; Harper KM; Ezzell JA; Lin FC; Beltran AS; Moy SS; Cohen TJ
Elife; 2023 Oct; 12():. PubMed ID: 37819053
[TBL] [Abstract][Full Text] [Related]
14. Endogenous TDP-43 mislocalization in a novel knock-in mouse model reveals DNA repair impairment, inflammation, and neuronal senescence.
Mitra J; Dharmalingam P; Kodavati M; Guerrero EN; Rao KS; Garruto RM; Hegde ML
Res Sq; 2024 Mar; ():. PubMed ID: 38343852
[TBL] [Abstract][Full Text] [Related]
15. Lower motor neuron involvement in TAR DNA-binding protein of 43 kDa-related frontotemporal lobar degeneration and amyotrophic lateral sclerosis.
Riku Y; Watanabe H; Yoshida M; Tatsumi S; Mimuro M; Iwasaki Y; Katsuno M; Iguchi Y; Masuda M; Senda J; Ishigaki S; Udagawa T; Sobue G
JAMA Neurol; 2014 Feb; 71(2):172-9. PubMed ID: 24378564
[TBL] [Abstract][Full Text] [Related]
16. Motor neuron TDP-43 proteinopathy in progressive supranuclear palsy and corticobasal degeneration.
Riku Y; Iwasaki Y; Ishigaki S; Akagi A; Hasegawa M; Nishioka K; Li Y; Riku M; Ikeuchi T; Fujioka Y; Miyahara H; Sone J; Hattori N; Yoshida M; Katsuno M; Sobue G
Brain; 2022 Aug; 145(8):2769-2784. PubMed ID: 35274674
[TBL] [Abstract][Full Text] [Related]
17. Developmentally Regulated RNA-binding Protein 1 (Drb1)/RNA-binding Motif Protein 45 (RBM45), a Nuclear-Cytoplasmic Trafficking Protein, Forms TAR DNA-binding Protein 43 (TDP-43)-mediated Cytoplasmic Aggregates.
Mashiko T; Sakashita E; Kasashima K; Tominaga K; Kuroiwa K; Nozaki Y; Matsuura T; Hamamoto T; Endo H
J Biol Chem; 2016 Jul; 291(29):14996-5007. PubMed ID: 27226551
[TBL] [Abstract][Full Text] [Related]
18. Retrotransposon activation contributes to neurodegeneration in a Drosophila TDP-43 model of ALS.
Krug L; Chatterjee N; Borges-Monroy R; Hearn S; Liao WW; Morrill K; Prazak L; Rozhkov N; Theodorou D; Hammell M; Dubnau J
PLoS Genet; 2017 Mar; 13(3):e1006635. PubMed ID: 28301478
[TBL] [Abstract][Full Text] [Related]
19. TDP-43 transports ribosomal protein mRNA to regulate axonal local translation in neuronal axons.
Nagano S; Jinno J; Abdelhamid RF; Jin Y; Shibata M; Watanabe S; Hirokawa S; Nishizawa M; Sakimura K; Onodera O; Okada H; Okada T; Saito Y; Takahashi-Fujigasaki J; Murayama S; Wakatsuki S; Mochizuki H; Araki T
Acta Neuropathol; 2020 Nov; 140(5):695-713. PubMed ID: 32803350
[TBL] [Abstract][Full Text] [Related]
20. Induction of autophagy mitigates TDP-43 pathology and translational repression of neurofilament mRNAs in mouse models of ALS/FTD.
Kumar S; Phaneuf D; Cordeau P; Boutej H; Kriz J; Julien JP
Mol Neurodegener; 2021 Jan; 16(1):1. PubMed ID: 33413517
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]