BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

213 related articles for article (PubMed ID: 33415684)

  • 1. In vivo Validation of Bimolecular Fluorescence Complementation (BiFC) to Investigate Aggregate Formation in Amyotrophic Lateral Sclerosis (ALS).
    Don EK; Maschirow A; Radford RAW; Scherer NM; Vidal-Itriago A; Hogan A; Maurel C; Formella I; Stoddart JJ; Hall TE; Lee A; Shi B; Cole NJ; Laird AS; Badrock AP; Chung RS; Morsch M
    Mol Neurobiol; 2021 May; 58(5):2061-2074. PubMed ID: 33415684
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Pathological TDP-43 changes in Betz cells differ from those in bulbar and spinal α-motoneurons in sporadic amyotrophic lateral sclerosis.
    Braak H; Ludolph AC; Neumann M; Ravits J; Del Tredici K
    Acta Neuropathol; 2017 Jan; 133(1):79-90. PubMed ID: 27757524
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Dipeptide repeat protein inclusions are rare in the spinal cord and almost absent from motor neurons in C9ORF72 mutant amyotrophic lateral sclerosis and are unlikely to cause their degeneration.
    Gomez-Deza J; Lee YB; Troakes C; Nolan M; Al-Sarraj S; Gallo JM; Shaw CE
    Acta Neuropathol Commun; 2015 Jun; 3():38. PubMed ID: 26108573
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Spinal motor neuron protein supersaturation patterns are associated with inclusion body formation in ALS.
    Ciryam P; Lambert-Smith IA; Bean DM; Freer R; Cid F; Tartaglia GG; Saunders DN; Wilson MR; Oliver SG; Morimoto RI; Dobson CM; Vendruscolo M; Favrin G; Yerbury JJ
    Proc Natl Acad Sci U S A; 2017 May; 114(20):E3935-E3943. PubMed ID: 28396410
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Optogenetic modulation of TDP-43 oligomerization accelerates ALS-related pathologies in the spinal motor neurons.
    Asakawa K; Handa H; Kawakami K
    Nat Commun; 2020 Feb; 11(1):1004. PubMed ID: 32081878
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Targeted depletion of TDP-43 expression in the spinal cord motor neurons leads to the development of amyotrophic lateral sclerosis-like phenotypes in mice.
    Wu LS; Cheng WC; Shen CK
    J Biol Chem; 2012 Aug; 287(33):27335-44. PubMed ID: 22718760
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A robust TDP-43 knock-in mouse model of ALS.
    Huang SL; Wu LS; Lee M; Chang CW; Cheng WC; Fang YS; Chen YR; Cheng PL; Shen CJ
    Acta Neuropathol Commun; 2020 Jan; 8(1):3. PubMed ID: 31964415
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The metastability of the proteome of spinal motor neurons underlies their selective vulnerability in ALS.
    Yerbury JJ; Ooi L; Blair IP; Ciryam P; Dobson CM; Vendruscolo M
    Neurosci Lett; 2019 Jun; 704():89-94. PubMed ID: 30953736
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Low molecular weight species of TDP-43 generated by abnormal splicing form inclusions in amyotrophic lateral sclerosis and result in motor neuron death.
    Xiao S; Sanelli T; Chiang H; Sun Y; Chakrabartty A; Keith J; Rogaeva E; Zinman L; Robertson J
    Acta Neuropathol; 2015 Jul; 130(1):49-61. PubMed ID: 25788357
    [TBL] [Abstract][Full Text] [Related]  

  • 10. TDP-43 aggregation inside micronuclei reveals a potential mechanism for protein inclusion formation in ALS.
    Droppelmann CA; Campos-Melo D; Moszczynski AJ; Amzil H; Strong MJ
    Sci Rep; 2019 Dec; 9(1):19928. PubMed ID: 31882736
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Review: Prion-like mechanisms of transactive response DNA binding protein of 43 kDa (TDP-43) in amyotrophic lateral sclerosis (ALS).
    Smethurst P; Sidle KC; Hardy J
    Neuropathol Appl Neurobiol; 2015 Aug; 41(5):578-97. PubMed ID: 25487060
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Enrichment of C-terminal fragments in TAR DNA-binding protein-43 cytoplasmic inclusions in brain but not in spinal cord of frontotemporal lobar degeneration and amyotrophic lateral sclerosis.
    Igaz LM; Kwong LK; Xu Y; Truax AC; Uryu K; Neumann M; Clark CM; Elman LB; Miller BL; Grossman M; McCluskey LF; Trojanowski JQ; Lee VM
    Am J Pathol; 2008 Jul; 173(1):182-94. PubMed ID: 18535185
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Combined fused in sarcoma-positive (FUS+) basophilic inclusion body disease and atypical tauopathy presenting with an amyotrophic lateral sclerosis/motor neurone disease (ALS/MND)-plus phenotype.
    Wharton SB; Verber NS; Wagner BE; Highley JR; Fillingham DJ; Waller R; Strand K; Ince PG; Shaw PJ
    Neuropathol Appl Neurobiol; 2019 Oct; 45(6):586-596. PubMed ID: 30659642
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Characteristic Features of FUS Inclusions in Spinal Motor Neurons of Sporadic Amyotrophic Lateral Sclerosis.
    Ikenaka K; Ishigaki S; Iguchi Y; Kawai K; Fujioka Y; Yokoi S; Abdelhamid RF; Nagano S; Mochizuki H; Katsuno M; Sobue G
    J Neuropathol Exp Neurol; 2020 Apr; 79(4):370-377. PubMed ID: 32142134
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Loss of hnRNPA1 in ALS spinal cord motor neurons with TDP-43-positive inclusions.
    Honda H; Hamasaki H; Wakamiya T; Koyama S; Suzuki SO; Fujii N; Iwaki T
    Neuropathology; 2015 Feb; 35(1):37-43. PubMed ID: 25338872
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Decreased number of Gemini of coiled bodies and U12 snRNA level in amyotrophic lateral sclerosis.
    Ishihara T; Ariizumi Y; Shiga A; Kato T; Tan CF; Sato T; Miki Y; Yokoo M; Fujino T; Koyama A; Yokoseki A; Nishizawa M; Kakita A; Takahashi H; Onodera O
    Hum Mol Genet; 2013 Oct; 22(20):4136-47. PubMed ID: 23740936
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The long non-coding RNA nuclear-enriched abundant transcript 1_2 induces paraspeckle formation in the motor neuron during the early phase of amyotrophic lateral sclerosis.
    Nishimoto Y; Nakagawa S; Hirose T; Okano HJ; Takao M; Shibata S; Suyama S; Kuwako K; Imai T; Murayama S; Suzuki N; Okano H
    Mol Brain; 2013 Jul; 6():31. PubMed ID: 23835137
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Monomerization of TDP-43 is a key determinant for inducing TDP-43 pathology in amyotrophic lateral sclerosis.
    Oiwa K; Watanabe S; Onodera K; Iguchi Y; Kinoshita Y; Komine O; Sobue A; Okada Y; Katsuno M; Yamanaka K
    Sci Adv; 2023 Aug; 9(31):eadf6895. PubMed ID: 37540751
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Distinct responses of neurons and astrocytes to TDP-43 proteinopathy in amyotrophic lateral sclerosis.
    Smethurst P; Risse E; Tyzack GE; Mitchell JS; Taha DM; Chen YR; Newcombe J; Collinge J; Sidle K; Patani R
    Brain; 2020 Feb; 143(2):430-440. PubMed ID: 32040555
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Amyotrophic lateral sclerosis: dash-like accumulation of phosphorylated TDP-43 in somatodendritic and axonal compartments of somatomotor neurons of the lower brainstem and spinal cord.
    Braak H; Ludolph A; Thal DR; Del Tredici K
    Acta Neuropathol; 2010 Jul; 120(1):67-74. PubMed ID: 20379728
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.