151 related articles for article (PubMed ID: 33416017)
1. Comparison of quinazoline and benzoylpyrazoline chemotypes targeting the CaVα-β interaction as antagonists of the N-type CaV2.2 channel.
Ran D; Gomez K; Moutal A; Patek M; Perez-Miller S; Khanna R
Channels (Austin); 2021 Dec; 15(1):128-135. PubMed ID: 33416017
[TBL] [Abstract][Full Text] [Related]
2. Targeting the CaVα-CaVβ interaction yields an antagonist of the N-type CaV2.2 channel with broad antinociceptive efficacy.
Khanna R; Yu J; Yang X; Moutal A; Chefdeville A; Gokhale V; Shuja Z; Chew LA; Bellampalli SS; Luo S; François-Moutal L; Serafini MJ; Ha T; Perez-Miller S; Park KD; Patwardhan AM; Streicher JM; Colecraft HM; Khanna M
Pain; 2019 Jul; 160(7):1644-1661. PubMed ID: 30933958
[TBL] [Abstract][Full Text] [Related]
3. Interaction via a key tryptophan in the I-II linker of N-type calcium channels is required for beta1 but not for palmitoylated beta2, implicating an additional binding site in the regulation of channel voltage-dependent properties.
Leroy J; Richards MW; Butcher AJ; Nieto-Rostro M; Pratt WS; Davies A; Dolphin AC
J Neurosci; 2005 Jul; 25(30):6984-96. PubMed ID: 16049174
[TBL] [Abstract][Full Text] [Related]
4. Engineering selectivity into RGK GTPase inhibition of voltage-dependent calcium channels.
Puckerin AA; Chang DD; Shuja Z; Choudhury P; Scholz J; Colecraft HM
Proc Natl Acad Sci U S A; 2018 Nov; 115(47):12051-12056. PubMed ID: 30397133
[TBL] [Abstract][Full Text] [Related]
5. Inhibition of protein kinase C (PKC) response of voltage-gated calcium (Cav)2.2 channels expressed in Xenopus oocytes by Cavβ subunits.
Rajagopal S; Fields BL; Burton BK; On C; Reeder AA; Kamatchi GL
Neuroscience; 2014 Nov; 280():1-9. PubMed ID: 25218964
[TBL] [Abstract][Full Text] [Related]
6. Spinal Fbxo3-Dependent Fbxl2 Ubiquitination of Active Zone Protein RIM1α Mediates Neuropathic Allodynia through CaV2.2 Activation.
Lai CY; Ho YC; Hsieh MC; Wang HH; Cheng JK; Chau YP; Peng HY
J Neurosci; 2016 Sep; 36(37):9722-38. PubMed ID: 27629721
[TBL] [Abstract][Full Text] [Related]
7. Reversal of Peripheral Neuropathic Pain by the Small-Molecule Natural Product Physalin F via Block of CaV2.3 (R-Type) and CaV2.2 (N-Type) Voltage-Gated Calcium Channels.
Shan Z; Cai S; Yu J; Zhang Z; Vallecillo TGM; Serafini MJ; Thomas AM; Pham NYN; Bellampalli SS; Moutal A; Zhou Y; Xu GB; Xu YM; Luo S; Patek M; Streicher JM; Gunatilaka AAL; Khanna R
ACS Chem Neurosci; 2019 Jun; 10(6):2939-2955. PubMed ID: 30946560
[TBL] [Abstract][Full Text] [Related]
8. Small-molecule Ca
Chen X; Liu D; Zhou D; Si Y; Xu D; Stamatkin CW; Ghozayel MK; Ripsch MS; Obukhov AG; White FA; Meroueh SO
Proc Natl Acad Sci U S A; 2018 Nov; 115(45):E10566-E10575. PubMed ID: 30355767
[TBL] [Abstract][Full Text] [Related]
9. Novel CaV2.1 clone replicates many properties of Purkinje cell CaV2.1 current.
Richards KS; Swensen AM; Lipscombe D; Bommert K
Eur J Neurosci; 2007 Nov; 26(10):2950-61. PubMed ID: 18001290
[TBL] [Abstract][Full Text] [Related]
10. Upregulation of N-type calcium channels in the soma of uninjured dorsal root ganglion neurons contributes to neuropathic pain by increasing neuronal excitability following peripheral nerve injury.
Yang J; Xie MX; Hu L; Wang XF; Mai JZ; Li YY; Wu N; Zhang C; Li J; Pang RP; Liu XG
Brain Behav Immun; 2018 Jul; 71():52-65. PubMed ID: 29709527
[TBL] [Abstract][Full Text] [Related]
11. The CaVβ Subunit Protects the I-II Loop of the Voltage-gated Calcium Channel CaV2.2 from Proteasomal Degradation but Not Oligoubiquitination.
Page KM; Rothwell SW; Dolphin AC
J Biol Chem; 2016 Sep; 291(39):20402-16. PubMed ID: 27489103
[TBL] [Abstract][Full Text] [Related]
12. Translocatable voltage-gated Ca
Yeon JH; Park CG; Hille B; Suh BC
Proc Natl Acad Sci U S A; 2018 Oct; 115(42):E9934-E9943. PubMed ID: 30257950
[TBL] [Abstract][Full Text] [Related]
13. Conserved biophysical features of the Ca
Gauberg J; Abdallah S; Elkhatib W; Harracksingh AN; Piekut T; Stanley EF; Senatore A
J Biol Chem; 2020 Dec; 295(52):18553-18578. PubMed ID: 33097592
[TBL] [Abstract][Full Text] [Related]
14. An integrated multiassay approach to the discovery of small-molecule N-type voltage-gated calcium channel antagonists.
Finley MF; Lubin ML; Neeper MP; Beck E; Liu Y; Flores CM; Qin N
Assay Drug Dev Technol; 2010 Dec; 8(6):685-94. PubMed ID: 21050074
[TBL] [Abstract][Full Text] [Related]
15. Novel mechanism of voltage-gated N-type (Cav2.2) calcium channel inhibition revealed through α-conotoxin Vc1.1 activation of the GABA(B) receptor.
Huynh TG; Cuny H; Slesinger PA; Adams DJ
Mol Pharmacol; 2015 Feb; 87(2):240-50. PubMed ID: 25425625
[TBL] [Abstract][Full Text] [Related]
16. An ancestral MAGUK protein supports the modulation of mammalian voltage-gated Ca
Segura E; Mehta A; Marsolais M; Quan XR; Zhao J; Sauvé R; Spafford JD; Parent L
Biochim Biophys Acta Biomembr; 2020 Nov; 1862(11):183439. PubMed ID: 32814116
[TBL] [Abstract][Full Text] [Related]
17. Heat But Not Mechanical Hypersensitivity Depends on Voltage-Gated Ca
DuBreuil DM; Lopez Soto EJ; Daste S; Meir R; Li D; Wainger B; Fleischmann A; Lipscombe D
J Neurosci; 2021 Sep; 41(36):7546-7560. PubMed ID: 34353899
[TBL] [Abstract][Full Text] [Related]
18. Cross talk between β subunits, intracellular Ca
Serra SA; Gené GG; Elorza-Vidal X; Fernández-Fernández JM
Physiol Rep; 2018 Jan; 6(2):. PubMed ID: 29380539
[TBL] [Abstract][Full Text] [Related]
19. Analgesic effects of a substituted N-triazole oxindole (TROX-1), a state-dependent, voltage-gated calcium channel 2 blocker.
Abbadie C; McManus OB; Sun SY; Bugianesi RM; Dai G; Haedo RJ; Herrington JB; Kaczorowski GJ; Smith MM; Swensen AM; Warren VA; Williams B; Arneric SP; Eduljee C; Snutch TP; Tringham EW; Jochnowitz N; Liang A; Euan MacIntyre D; McGowan E; Mistry S; White VV; Hoyt SB; London C; Lyons KA; Bunting PB; Volksdorf S; Duffy JL
J Pharmacol Exp Ther; 2010 Aug; 334(2):545-55. PubMed ID: 20439438
[TBL] [Abstract][Full Text] [Related]
20. Up-regulation of Cavβ3 subunit in primary sensory neurons increases voltage-activated Ca2+ channel activity and nociceptive input in neuropathic pain.
Li L; Cao XH; Chen SR; Han HD; Lopez-Berestein G; Sood AK; Pan HL
J Biol Chem; 2012 Feb; 287(8):6002-13. PubMed ID: 22187436
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
