212 related articles for article (PubMed ID: 33420377)
1. Inhibition of PFKFB3 induces cell death and synergistically enhances chemosensitivity in endometrial cancer.
Xiao Y; Jin L; Deng C; Guan Y; Kalogera E; Ray U; Thirusangu P; Staub J; Sarkar Bhattacharya S; Xu H; Fang X; Shridhar V
Oncogene; 2021 Feb; 40(8):1409-1424. PubMed ID: 33420377
[TBL] [Abstract][Full Text] [Related]
2. Therapeutic targeting of PFKFB3 with a novel glycolytic inhibitor PFK158 promotes lipophagy and chemosensitivity in gynecologic cancers.
Mondal S; Roy D; Sarkar Bhattacharya S; Jin L; Jung D; Zhang S; Kalogera E; Staub J; Wang Y; Xuyang W; Khurana A; Chien J; Telang S; Chesney J; Tapolsky G; Petras D; Shridhar V
Int J Cancer; 2019 Jan; 144(1):178-189. PubMed ID: 30226266
[TBL] [Abstract][Full Text] [Related]
3. PFKFB3 inhibition reprograms malignant pleural mesothelioma to nutrient stress-induced macropinocytosis and ER stress as independent binary adaptive responses.
Sarkar Bhattacharya S; Thirusangu P; Jin L; Roy D; Jung D; Xiao Y; Staub J; Roy B; Molina JR; Shridhar V
Cell Death Dis; 2019 Sep; 10(10):725. PubMed ID: 31562297
[TBL] [Abstract][Full Text] [Related]
4. Small-molecule inhibition of 6-phosphofructo-2-kinase activity suppresses glycolytic flux and tumor growth.
Clem B; Telang S; Clem A; Yalcin A; Meier J; Simmons A; Rasku MA; Arumugam S; Dean WL; Eaton J; Lane A; Trent JO; Chesney J
Mol Cancer Ther; 2008 Jan; 7(1):110-20. PubMed ID: 18202014
[TBL] [Abstract][Full Text] [Related]
5. PFKFB3 Inhibition Attenuates Oxaliplatin-Induced Autophagy and Enhances Its Cytotoxicity in Colon Cancer Cells.
Yan S; Zhou N; Zhang D; Zhang K; Zheng W; Bao Y; Yang W
Int J Mol Sci; 2019 Oct; 20(21):. PubMed ID: 31671668
[TBL] [Abstract][Full Text] [Related]
6. Inhibition of glycolytic activator PFKFB3 suppresses tumor growth and induces tumor vessel normalization in hepatocellular carcinoma.
Matsumoto K; Noda T; Kobayashi S; Sakano Y; Yokota Y; Iwagami Y; Yamada D; Tomimaru Y; Akita H; Gotoh K; Takeda Y; Tanemura M; Umeshita K; Doki Y; Eguchi H
Cancer Lett; 2021 Mar; 500():29-40. PubMed ID: 33307155
[TBL] [Abstract][Full Text] [Related]
7. PFKFB3 regulates cancer stemness through the hippo pathway in small cell lung carcinoma.
Thirusangu P; Ray U; Sarkar Bhattacharya S; Oien DB; Jin L; Staub J; Kannan N; Molina JR; Shridhar V
Oncogene; 2022 Aug; 41(33):4003-4017. PubMed ID: 35804016
[TBL] [Abstract][Full Text] [Related]
8. KDM1A inhibition augments the efficacy of rapamycin for the treatment of endometrial cancer.
Venkata PP; Chen Y; Alejo S; He Y; Palacios BE; Loeffel I; Liu J; Pratap UP; Gray G; Achuthan Pillai SM; Zou Y; Lai Z; Suzuki T; Viswanadhapalli S; Palakurthi S; Tekmal RR; Vadlamudi RK; Kost E; Sareddy GR
Cancer Lett; 2022 Jan; 524():219-231. PubMed ID: 34673129
[TBL] [Abstract][Full Text] [Related]
9. Blockage of glycolysis by targeting PFKFB3 suppresses tumor growth and metastasis in head and neck squamous cell carcinoma.
Li HM; Yang JG; Liu ZJ; Wang WM; Yu ZL; Ren JG; Chen G; Zhang W; Jia J
J Exp Clin Cancer Res; 2017 Jan; 36(1):7. PubMed ID: 28061878
[TBL] [Abstract][Full Text] [Related]
10. PFKFB3 regulates breast cancer tumorigenesis and Fulvestrant sensitivity by affecting ERĪ± stability.
Jia W; Wu Q; Shen M; Yu X; An S; Zhao L; Huang G; Liu J
Cell Signal; 2024 Jul; 119():111184. PubMed ID: 38640982
[TBL] [Abstract][Full Text] [Related]
11. Increased 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase-3 activity in response to EGFR signaling contributes to non-small cell lung cancer cell survival.
Lypova N; Telang S; Chesney J; Imbert-Fernandez Y
J Biol Chem; 2019 Jul; 294(27):10530-10543. PubMed ID: 31126985
[TBL] [Abstract][Full Text] [Related]
12. PFKFB3 works on the FAK-STAT3-SOX2 axis to regulate the stemness in MPM.
Sarkar Bhattacharya S; Thirusangu P; Jin L; Staub J; Shridhar V; Molina JR
Br J Cancer; 2022 Oct; 127(7):1352-1364. PubMed ID: 35794237
[TBL] [Abstract][Full Text] [Related]
13. Dual inhibition of PFKFB3 and VEGF normalizes tumor vasculature, reduces lactate production, and improves chemotherapy in glioblastoma: insights from protein expression profiling and MRI.
Zhang J; Xue W; Xu K; Yi L; Guo Y; Xie T; Tong H; Zhou B; Wang S; Li Q; Liu H; Chen X; Fang J; Zhang W
Theranostics; 2020; 10(16):7245-7259. PubMed ID: 32641990
[No Abstract] [Full Text] [Related]
14. Expression of PFKFB3 and Ki67 in lung adenocarcinomas and targeting PFKFB3 as a therapeutic strategy.
Li X; Liu J; Qian L; Ke H; Yao C; Tian W; Liu Y; Zhang J
Mol Cell Biochem; 2018 Aug; 445(1-2):123-134. PubMed ID: 29327288
[TBL] [Abstract][Full Text] [Related]
15. 4-Acetylantroquinonol B suppresses autophagic flux and improves cisplatin sensitivity in highly aggressive epithelial cancer through the PI3K/Akt/mTOR/p70S6K signaling pathway.
Liu M; Bamodu OA; Huang WC; Zucha MA; Lin YK; Wu ATH; Huang CC; Lee WH; Yuan CC; Hsiao M; Deng L; Tzeng YM; Yeh CT
Toxicol Appl Pharmacol; 2017 Jun; 325():48-60. PubMed ID: 28408137
[TBL] [Abstract][Full Text] [Related]
16. Inhibition of PFKFB3 suppresses osteoclastogenesis and prevents ovariectomy-induced bone loss.
Wang J; Guan H; Liu H; Lei Z; Kang H; Guo Q; Dong Y; Liu H; Sun Y; Fang Z; Li F
J Cell Mol Med; 2020 Feb; 24(3):2294-2307. PubMed ID: 31880389
[TBL] [Abstract][Full Text] [Related]
17. Inhibition of 6-phosphofructo-2-kinase (PFKFB3) suppresses glucose metabolism and the growth of HER2+ breast cancer.
O'Neal J; Clem A; Reynolds L; Dougherty S; Imbert-Fernandez Y; Telang S; Chesney J; Clem BF
Breast Cancer Res Treat; 2016 Nov; 160(1):29-40. PubMed ID: 27613609
[TBL] [Abstract][Full Text] [Related]
18. Effects of endoplasmic reticulum stress on the autophagy, apoptosis, and chemotherapy resistance of human breast cancer cells by regulating the PI3K/AKT/mTOR signaling pathway.
Zhong JT; Yu J; Wang HJ; Shi Y; Zhao TS; He BX; Qiao B; Feng ZW
Tumour Biol; 2017 May; 39(5):1010428317697562. PubMed ID: 28459209
[TBL] [Abstract][Full Text] [Related]
19. Co-treatment with BEZ235 enhances chemosensitivity of A549/DDP cells to cisplatin via inhibition of PI3K/Akt/mTOR signaling and downregulation of ERCC1 expression.
Xia A; Li H; Li R; Lu L; Wu X
Oncol Rep; 2018 Oct; 40(4):2353-2362. PubMed ID: 30066933
[TBL] [Abstract][Full Text] [Related]
20. The synergistic effect of PFK15 with metformin exerts anti-myeloma activity via PFKFB3.
Liu X; Zhao Y; Zhang E; Yan H; Lv N; Cai Z
Biochem Biophys Res Commun; 2019 Jul; 515(2):332-338. PubMed ID: 31153642
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]