These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

293 related articles for article (PubMed ID: 33421913)

  • 1. Synthesis and bioevaluation of N-(3,4,5-trimethoxyphenyl)-1H-pyrazolo[3,4-b]pyridin-3-amines as tubulin polymerization inhibitors with anti-angiogenic effects.
    Hao SY; Qi ZY; Wang S; Wang XR; Chen SW
    Bioorg Med Chem; 2021 Feb; 31():115985. PubMed ID: 33421913
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Design, synthesis, and bioevaluation of pyrazolo[1,5-a]pyrimidine derivatives as tubulin polymerization inhibitors targeting the colchicine binding site with potent anticancer activities.
    Li G; Wang Y; Li L; Ren Y; Deng X; Liu J; Wang W; Luo M; Liu S; Chen J
    Eur J Med Chem; 2020 Sep; 202():112519. PubMed ID: 32650183
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Design, synthesis and bioevaluation of 2,7-diaryl-pyrazolo[1,5-a]pyrimidines as tubulin polymerization inhibitors.
    Liu R; Zhang S; Huang M; Guo Z; Li L; Li M; Wu L; Guan Q; Zhang W
    Bioorg Chem; 2021 Oct; 115():105220. PubMed ID: 34352709
    [TBL] [Abstract][Full Text] [Related]  

  • 4. 3,5-Diaryl-1H-pyrazolo[3,4-b]pyridines as potent tubulin polymerization inhibitors: Rational design, synthesis and biological evaluation.
    Zhai M; Liu S; Gao M; Wang L; Sun J; Du J; Guan Q; Bao K; Zuo D; Wu Y; Zhang W
    Eur J Med Chem; 2019 Apr; 168():426-435. PubMed ID: 30831410
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis and biological evaluation of N-alkyl-N-(4-methoxyphenyl)pyridin-2-amines as a new class of tubulin polymerization inhibitors.
    Wang XF; Ohkoshi E; Wang SB; Hamel E; Bastow KF; Morris-Natschke SL; Lee KH; Xie L
    Bioorg Med Chem; 2013 Feb; 21(3):632-42. PubMed ID: 23274123
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Design, synthesis and bioevaluation of 6-aryl-1-(3,4,5-trimethoxyphenyl)-1H-benzo[d]imidazoles as tubulin polymerization inhibitors.
    Liu R; Huang M; Zhang S; Li L; Li M; Sun J; Wu L; Guan Q; Zhang W
    Eur J Med Chem; 2021 Dec; 226():113826. PubMed ID: 34571171
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Design, synthesis and biological evaluation of novel pyrazoline-containing derivatives as potential tubulin assembling inhibitors.
    Qin YJ; Li YJ; Jiang AQ; Yang MR; Zhu QZ; Dong H; Zhu HL
    Eur J Med Chem; 2015 Apr; 94():447-57. PubMed ID: 25828827
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis and biological evaluation of (1-aryl-1H-pyrazol-4-yl) (3,4,5-trimethoxyphenyl)methanone derivatives as tubulin inhibitors.
    Zhai M; Wang L; Liu S; Wang L; Yan P; Wang J; Zhang J; Guo H; Guan Q; Bao K; Wu Y; Zhang W
    Eur J Med Chem; 2018 Aug; 156():137-147. PubMed ID: 30006160
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Discovery and optimization of 3,4,5-trimethoxyphenyl substituted triazolylthioacetamides as potent tubulin polymerization inhibitors.
    Yang F; He CP; Diao PC; Hong KH; Rao JJ; Zhao PL
    Bioorg Med Chem Lett; 2019 Jan; 29(1):22-27. PubMed ID: 30448234
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis and biological evaluation of curcumin inspired imidazo[1,2-a]pyridine analogues as tubulin polymerization inhibitors.
    Ramya PVS; Guntuku L; Angapelly S; Digwal CS; Lakshmi UJ; Sigalapalli DK; Babu BN; Naidu VGM; Kamal A
    Eur J Med Chem; 2018 Jan; 143():216-231. PubMed ID: 29174816
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis, biological evaluation, and structure-activity relationships of new tubulin polymerization inhibitors based on 5-amino-1,2,4-triazole scaffold.
    Yang F; Chen L; Lai JM; Jian XE; Lv DX; Yuan LL; Liu YX; Liang FT; Zheng XL; Li XL; Wei LY; You WW; Zhao PL
    Bioorg Med Chem Lett; 2021 Apr; 38():127880. PubMed ID: 33636303
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis and biological evaluation of novel pyrazolo[3,4-b]pyridines as cis-restricted combretastatin A-4 analogues.
    Jian XE; Yang F; Jiang CS; You WW; Zhao PL
    Bioorg Med Chem Lett; 2020 Apr; 30(8):127025. PubMed ID: 32063430
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Hybrid Pharmacophore Design, Molecular Docking, Synthesis, and Biological Evaluation of Novel Aldimine-Type Schiff Base Derivatives as Tubulin Polymerization Inhibitor.
    Ameri A; Khodarahmi G; Forootanfar H; Hassanzadeh F; Hakimelahi GH
    Chem Biodivers; 2018 Mar; 15(3):e1700518. PubMed ID: 29292595
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis, biological evaluation and molecular docking of benzimidazole grafted benzsulfamide-containing pyrazole ring derivatives as novel tubulin polymerization inhibitors.
    Wang YT; Shi TQ; Zhu HL; Liu CH
    Bioorg Med Chem; 2019 Feb; 27(3):502-515. PubMed ID: 30606674
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Design and synthesis of 4-morpholino-6-(1,2,3,6-tetrahydropyridin-4-yl)-N-(3,4,5-trimethoxyphenyl)-1,3,5-triazin-2-amine analogues as tubulin polymerization inhibitors.
    Narva S; Chitti S; Amaroju S; Bhattacharjee D; Rao BB; Jain N; Alvala M; Sekhar KVGC
    Bioorg Med Chem Lett; 2017 Aug; 27(16):3794-3801. PubMed ID: 28684120
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Design, synthesis and biological evaluation of novel thiazole-naphthalene derivatives as potential anticancer agents and tubulin polymerisation inhibitors.
    Wang G; Liu W; Fan M; He M; Li Y; Peng Z
    J Enzyme Inhib Med Chem; 2021 Dec; 36(1):1694-1702. PubMed ID: 34309466
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis of Combretastatin-A4 Carboxamidest that Mimic Sulfonyl Piperazines by a Molecular Hybridization Approach: in vitro Cytotoxicity Evaluation and Inhibition of Tubulin Polymerization.
    Jadala C; Sathish M; Anchi P; Tokala R; Lakshmi UJ; Reddy VG; Shankaraiah N; Godugu C; Kamal A
    ChemMedChem; 2019 Dec; 14(24):2052-2060. PubMed ID: 31674147
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Discovery, biological evaluation, structure-activity relationships and mechanism of action of pyrazolo[3,4-b]pyridin-6-one derivatives as a new class of anticancer agents.
    Guo Q; Luo Y; Zhai S; Jiang Z; Zhao C; Xu J; Wang L
    Org Biomol Chem; 2019 Jun; 17(25):6201-6214. PubMed ID: 31179474
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Discovery of novel 2-substituted 2, 3-dihydroquinazolin-4(1H)-one derivatives as tubulin polymerization inhibitors for anticancer therapy: The in vitro and in vivo biological evaluation.
    Shi C; Yang B; He Z; Yang J; Li L; Song J; Xu S; Song W; Yang J
    Eur J Med Chem; 2024 Nov; 277():116766. PubMed ID: 39163776
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Design and synthesis of novel imidazole-chalcone derivatives as microtubule protein polymerization inhibitors to treat cervical cancer and reverse cisplatin resistance.
    Liu Z; Yang Z; Ablise M
    Bioorg Chem; 2024 Jun; 147():107310. PubMed ID: 38583249
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.