BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

123 related articles for article (PubMed ID: 33422770)

  • 1. Up-regulation of multidrug resistance protein MDR1/ABCB1 in carfilzomib-resistant multiple myeloma differentially affects efficacy of anti-myeloma drugs.
    Byrgazov K; Kraus M; Besse A; Slipicevic A; Lehmann F; Driessen C; Besse L
    Leuk Res; 2021 Feb; 101():106499. PubMed ID: 33422770
    [No Abstract]   [Full Text] [Related]  

  • 2. Lapatinib (Tykerb, GW572016) reverses multidrug resistance in cancer cells by inhibiting the activity of ATP-binding cassette subfamily B member 1 and G member 2.
    Dai CL; Tiwari AK; Wu CP; Su XD; Wang SR; Liu DG; Ashby CR; Huang Y; Robey RW; Liang YJ; Chen LM; Shi CJ; Ambudkar SV; Chen ZS; Fu LW
    Cancer Res; 2008 Oct; 68(19):7905-14. PubMed ID: 18829547
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Identification of an ABCB1 (P-glycoprotein)-positive carfilzomib-resistant myeloma subpopulation by the pluripotent stem cell fluorescent dye CDy1.
    Hawley TS; Riz I; Yang W; Wakabayashi Y; Depalma L; Chang YT; Peng W; Zhu J; Hawley RG
    Am J Hematol; 2013 Apr; 88(4):265-72. PubMed ID: 23475625
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Tetrandrine Interaction with ABCB1 Reverses Multidrug Resistance in Cancer Cells Through Competition with Anti-Cancer Drugs Followed by Downregulation of ABCB1 Expression.
    Liao D; Zhang W; Gupta P; Lei ZN; Wang JQ; Cai CY; Vera AA; Zhang L; Chen ZS; Yang DH
    Molecules; 2019 Nov; 24(23):. PubMed ID: 31801248
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Carfilzomib resistance due to ABCB1/MDR1 overexpression is overcome by nelfinavir and lopinavir in multiple myeloma.
    Besse A; Stolze SC; Rasche L; Weinhold N; Morgan GJ; Kraus M; Bader J; Overkleeft HS; Besse L; Driessen C
    Leukemia; 2018 Feb; 32(2):391-401. PubMed ID: 28676669
    [TBL] [Abstract][Full Text] [Related]  

  • 6. By inhibiting Src, verapamil and dasatinib overcome multidrug resistance via increased expression of Bim and decreased expressions of MDR1 and survivin in human multidrug-resistant myeloma cells.
    Tsubaki M; Komai M; Itoh T; Imano M; Sakamoto K; Shimaoka H; Takeda T; Ogawa N; Mashimo K; Fujiwara D; Mukai J; Sakaguchi K; Satou T; Nishida S
    Leuk Res; 2014 Jan; 38(1):121-30. PubMed ID: 24239173
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Inhibition of multidrug resistance by adamantylgb3, a globotriaosylceramide analog.
    De Rosa MF; Ackerley C; Wang B; Ito S; Clarke DM; Lingwood C
    J Biol Chem; 2008 Feb; 283(8):4501-11. PubMed ID: 18003606
    [TBL] [Abstract][Full Text] [Related]  

  • 8. ABCG2 expression, function, and promoter methylation in human multiple myeloma.
    Turner JG; Gump JL; Zhang C; Cook JM; Marchion D; Hazlehurst L; Munster P; Schell MJ; Dalton WS; Sullivan DM
    Blood; 2006 Dec; 108(12):3881-9. PubMed ID: 16917002
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Proteasome inhibitor-adapted myeloma cells are largely independent from proteasome activity and show complex proteomic changes, in particular in redox and energy metabolism.
    Soriano GP; Besse L; Li N; Kraus M; Besse A; Meeuwenoord N; Bader J; Everts B; den Dulk H; Overkleeft HS; Florea BI; Driessen C
    Leukemia; 2016 Nov; 30(11):2198-2207. PubMed ID: 27118406
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Thalidomide alters nuclear architecture without ABCB1 gene modulation in drug-resistant myeloma cells.
    Trussardi-Regnier A; Lavenus S; Gorisse MC; Dufer J
    Int J Oncol; 2009 Sep; 35(3):641-7. PubMed ID: 19639185
    [TBL] [Abstract][Full Text] [Related]  

  • 11. KLF4-SQSTM1/p62-associated prosurvival autophagy contributes to carfilzomib resistance in multiple myeloma models.
    Riz I; Hawley TS; Hawley RG
    Oncotarget; 2015 Jun; 6(17):14814-31. PubMed ID: 26109433
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Down-regulation of CD98 in melphalan-resistant myeloma cells with reduced drug uptake.
    Harada N; Nagasaki A; Hata H; Matsuzaki H; Matsuno F; Mitsuya H
    Acta Haematol; 2000; 103(3):144-51. PubMed ID: 10940652
    [TBL] [Abstract][Full Text] [Related]  

  • 13. XPO1 inhibitor combination therapy with bortezomib or carfilzomib induces nuclear localization of IκBα and overcomes acquired proteasome inhibitor resistance in human multiple myeloma.
    Turner JG; Kashyap T; Dawson JL; Gomez J; Bauer AA; Grant S; Dai Y; Shain KH; Meads M; Landesman Y; Sullivan DM
    Oncotarget; 2016 Nov; 7(48):78896-78909. PubMed ID: 27806331
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Dacomitinib antagonizes multidrug resistance (MDR) in cancer cells by inhibiting the efflux activity of ABCB1 and ABCG2 transporters.
    Fan YF; Zhang W; Zeng L; Lei ZN; Cai CY; Gupta P; Yang DH; Cui Q; Qin ZD; Chen ZS; Trombetta LD
    Cancer Lett; 2018 May; 421():186-198. PubMed ID: 29331420
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Structure, function and regulation of P-glycoprotein and its clinical relevance in drug disposition.
    Zhou SF
    Xenobiotica; 2008 Jul; 38(7-8):802-32. PubMed ID: 18668431
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Modulation of MDR1 and MRP3 gene expression in lung cancer cells after paclitaxel and carboplatin exposure.
    Melguizo C; Prados J; Luque R; Ortiz R; Caba O; Alvarez PJ; Gonzalez B; Aranega A
    Int J Mol Sci; 2012 Dec; 13(12):16624-35. PubMed ID: 23443122
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Diverse cross-resistance phenotype to ET-743 and PM00104 in multi-drug resistant cell lines.
    Duan Z; Choy E; Jimeno JM; Cuevas Cdel M; Mankin HJ; Hornicek FJ
    Cancer Chemother Pharmacol; 2009 May; 63(6):1121-9. PubMed ID: 18828019
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Not only P-glycoprotein: Amplification of the ABCB1-containing chromosome region 7q21 confers multidrug resistance upon cancer cells by coordinated overexpression of an assortment of resistance-related proteins.
    Genovese I; Ilari A; Assaraf YG; Fazi F; Colotti G
    Drug Resist Updat; 2017 May; 32():23-46. PubMed ID: 29145976
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Reversal effect of FW-04-806, a macrolide dilactone compound, on multidrug resistance mediated by ABCB1 and ABCG2 in vitro and in vivo.
    Zhang Z; Ma C; Li P; Wu M; Ye S; Fu L; Xu J
    Cell Commun Signal; 2019 Sep; 17(1):110. PubMed ID: 31472682
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Hydroxychloroquine potentiates carfilzomib toxicity towards myeloma cells.
    Baranowska K; Misund K; Starheim KK; Holien T; Johansson I; Darvekar S; Buene G; Waage A; Bjørkøy G; Sundan A
    Oncotarget; 2016 Oct; 7(43):70845-70856. PubMed ID: 27683126
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.