These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

228 related articles for article (PubMed ID: 33427574)

  • 21. Engineering Highly Potent and Selective Microproteins against Nav1.7 Sodium Channel for Treatment of Pain.
    Shcherbatko A; Rossi A; Foletti D; Zhu G; Bogin O; Galindo Casas M; Rickert M; Hasa-Moreno A; Bartsevich V; Crameri A; Steiner AR; Henningsen R; Gill A; Pons J; Shelton DL; Rajpal A; Strop P
    J Biol Chem; 2016 Jul; 291(27):13974-13986. PubMed ID: 27129258
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Development of Photocrosslinking Probes Based on Huwentoxin-IV to Map the Site of Interaction on Nav1.7.
    Tzakoniati F; Xu H; Li T; Garcia N; Kugel C; Payandeh J; Koth CM; Tate EW
    Cell Chem Biol; 2020 Mar; 27(3):306-313.e4. PubMed ID: 31732432
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Insensitivity to pain induced by a potent selective closed-state Nav1.7 inhibitor.
    Flinspach M; Xu Q; Piekarz AD; Fellows R; Hagan R; Gibbs A; Liu Y; Neff RA; Freedman J; Eckert WA; Zhou M; Bonesteel R; Pennington MW; Eddinger KA; Yaksh TL; Hunter M; Swanson RV; Wickenden AD
    Sci Rep; 2017 Jan; 7():39662. PubMed ID: 28045073
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Structural Basis for High-Affinity Trapping of the Na
    Wisedchaisri G; Tonggu L; Gamal El-Din TM; McCord E; Zheng N; Catterall WA
    Mol Cell; 2021 Jan; 81(1):38-48.e4. PubMed ID: 33232657
    [TBL] [Abstract][Full Text] [Related]  

  • 25. A spider-venom peptide with multitarget activity on sodium and calcium channels alleviates chronic visceral pain in a model of irritable bowel syndrome.
    Cardoso FC; Castro J; Grundy L; Schober G; Garcia-Caraballo S; Zhao T; Herzig V; King GF; Brierley SM; Lewis RJ
    Pain; 2021 Feb; 162(2):569-581. PubMed ID: 32826759
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Computational design of peptides to target Na
    Nguyen PT; Nguyen HM; Wagner KM; Stewart RG; Singh V; Thapa P; Chen YJ; Lillya MW; Ton AT; Kondo R; Ghetti A; Pennington MW; Hammock B; Griffith TN; Sack JT; Wulff H; Yarov-Yarovoy V
    Elife; 2022 Dec; 11():. PubMed ID: 36576241
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Discovery of Tarantula Venom-Derived Na
    Wu B; Murray JK; Andrews KL; Sham K; Long J; Aral J; Ligutti J; Amagasu S; Liu D; Zou A; Min X; Wang Z; Ilch CP; Kornecook TJ; Lin MJ; Be X; Miranda LP; Moyer BD; Biswas K
    J Med Chem; 2018 Nov; 61(21):9500-9512. PubMed ID: 30346167
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Natural mutations change the affinity of μ-theraphotoxin-Hhn2a to voltage-gated sodium channels.
    Zhang F; Liu Y; Zhang C; Li J; Yang Z; Gong X; Gan Y; Chen P; Liu Z; Liang S
    Toxicon; 2015 Jan; 93():24-30. PubMed ID: 25447770
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Manipulation of a spider peptide toxin alters its affinity for lipid bilayers and potency and selectivity for voltage-gated sodium channel subtype 1.7.
    Agwa AJ; Tran P; Mueller A; Tran HNT; Deuis JR; Israel MR; McMahon KL; Craik DJ; Vetter I; Schroeder CI
    J Biol Chem; 2020 Apr; 295(15):5067-5080. PubMed ID: 32139508
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Engineering potent and selective analogues of GpTx-1, a tarantula venom peptide antagonist of the Na(V)1.7 sodium channel.
    Murray JK; Ligutti J; Liu D; Zou A; Poppe L; Li H; Andrews KL; Moyer BD; McDonough SI; Favreau P; Stöcklin R; Miranda LP
    J Med Chem; 2015 Mar; 58(5):2299-314. PubMed ID: 25658507
    [TBL] [Abstract][Full Text] [Related]  

  • 31. General mechanism of spider toxin family I acting on sodium channel Nav1.7.
    Yuan FC; Sun FD; Zhang L; Huang B; An HL; Rong MQ; Du CW
    Zool Res; 2022 Sep; 43(5):886-896. PubMed ID: 36052553
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Challenges and Opportunities for Therapeutics Targeting the Voltage-Gated Sodium Channel Isoform Na
    Mulcahy JV; Pajouhesh H; Beckley JT; Delwig A; Du Bois J; Hunter JC
    J Med Chem; 2019 Oct; 62(19):8695-8710. PubMed ID: 31012583
    [TBL] [Abstract][Full Text] [Related]  

  • 33. A Novel Toxin from Haplopelma lividum Selectively Inhibits the Na
    Meng P; Huang H; Wang G; Yang S; Lu Q; Liu J; Lai R; Rong M
    Toxins (Basel); 2016 Dec; 9(1):. PubMed ID: 28035974
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Gating modifier toxins isolated from spider venom: Modulation of voltage-gated sodium channels and the role of lipid membranes.
    Agwa AJ; Peigneur S; Chow CY; Lawrence N; Craik DJ; Tytgat J; King GF; Henriques ST; Schroeder CI
    J Biol Chem; 2018 Jun; 293(23):9041-9052. PubMed ID: 29703751
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Newly Discovered Action of HpTx3 from Venom of Heteropoda
    Wu X; Wang Z; Chen Y; Xu D; Zhang P; Wang X
    Toxins (Basel); 2019 Nov; 11(12):. PubMed ID: 31757020
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Engineering Gain-of-Function Analogues of the Spider Venom Peptide HNTX-I, A Potent Blocker of the hNa
    Zhang Y; Yang Q; Zhang Q; Peng D; Chen M; Liang S; Zhou X; Liu Z
    Toxins (Basel); 2018 Sep; 10(9):. PubMed ID: 30181499
    [TBL] [Abstract][Full Text] [Related]  

  • 37. A complicated complex: Ion channels, voltage sensing, cell membranes and peptide inhibitors.
    Zhang AH; Sharma G; Undheim EAB; Jia X; Mobli M
    Neurosci Lett; 2018 Jul; 679():35-47. PubMed ID: 29684532
    [TBL] [Abstract][Full Text] [Related]  

  • 38. The Role of Disulfide Bond Replacements in Analogues of the Tarantula Toxin ProTx-II and Their Effects on Inhibition of the Voltage-Gated Sodium Ion Channel Na
    Wright ZVF; McCarthy S; Dickman R; Reyes FE; Sanchez-Martinez S; Cryar A; Kilford I; Hall A; Takle AK; Topf M; Gonen T; Thalassinos K; Tabor AB
    J Am Chem Soc; 2017 Sep; 139(37):13063-13075. PubMed ID: 28880078
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Discovery of a selective NaV1.7 inhibitor from centipede venom with analgesic efficacy exceeding morphine in rodent pain models.
    Yang S; Xiao Y; Kang D; Liu J; Li Y; Undheim EA; Klint JK; Rong M; Lai R; King GF
    Proc Natl Acad Sci U S A; 2013 Oct; 110(43):17534-9. PubMed ID: 24082113
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Engineering Na
    Murray JK; Wu B; Tegley CM; Nixey TE; Falsey JR; Herberich B; Yin L; Sham K; Long J; Aral J; Cheng Y; Netirojjanakul C; Doherty L; Glaus C; Ikotun T; Li H; Tran L; Soto M; Salimi-Moosavi H; Ligutti J; Amagasu S; Andrews KL; Be X; Lin MJ; Foti RS; Ilch CP; Youngblood B; Kornecook TJ; Karow M; Walker KW; Moyer BD; Biswas K; Miranda LP
    ACS Chem Biol; 2019 Apr; 14(4):806-818. PubMed ID: 30875193
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 12.