These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
2. In vitro Multistage Malaria Transmission Blocking Activity of Selected Malaria Box Compounds. Malebo HM; D'Alessandro S; Ebstie YA; Sorè H; Tenoh Guedoung AR; Katani SJ; Parapini S; Taramelli D; Habluetzel A Drug Des Devel Ther; 2020; 14():1593-1607. PubMed ID: 32425505 [TBL] [Abstract][Full Text] [Related]
3. Identification of MMV malaria box inhibitors of plasmodium falciparum early-stage gametocytes using a luciferase-based high-throughput assay. Lucantoni L; Duffy S; Adjalley SH; Fidock DA; Avery VM Antimicrob Agents Chemother; 2013 Dec; 57(12):6050-62. PubMed ID: 24060871 [TBL] [Abstract][Full Text] [Related]
4. Probing the Open Global Health Chemical Diversity Library for Multistage-Active Starting Points for Next-Generation Antimalarials. Abraham M; Gagaring K; Martino ML; Vanaerschot M; Plouffe DM; Calla J; Godinez-Macias KP; Du AY; Wree M; Antonova-Koch Y; Eribez K; Luth MR; Ottilie S; Fidock DA; McNamara CW; Winzeler EA ACS Infect Dis; 2020 Apr; 6(4):613-628. PubMed ID: 32078764 [TBL] [Abstract][Full Text] [Related]
5. The Tuberculosis Drug Candidate SQ109 and Its Analogs Have Multistage Activity against Watson SJ; van der Watt ME; Theron A; Reader J; Tshabalala S; Erlank E; Koekemoer LL; Naude M; Stampolaki M; Adewole F; Sadowska K; Pérez-Lozano P; Turcu AL; Vázquez S; Ko J; Mazurek B; Singh D; Malwal SR; Njoroge M; Chibale K; Onajole OK; Kolocouris A; Oldfield E; Birkholtz LM ACS Infect Dis; 2024 Sep; 10(9):3358-3367. PubMed ID: 39143042 [TBL] [Abstract][Full Text] [Related]
6. Metabolomic Profiling of the Malaria Box Reveals Antimalarial Target Pathways. Allman EL; Painter HJ; Samra J; Carrasquilla M; Llinás M Antimicrob Agents Chemother; 2016 Nov; 60(11):6635-6649. PubMed ID: 27572391 [TBL] [Abstract][Full Text] [Related]
7. Multistage and transmission-blocking tubulin targeting potent antimalarial discovered from the open access MMV pathogen box. Kumari G; Jain R; Kumar Sah R; Kalia I; Vashistha M; Singh P; Prasad Singh A; Samby K; Burrows J; Singh S Biochem Pharmacol; 2022 Sep; 203():115154. PubMed ID: 35798201 [TBL] [Abstract][Full Text] [Related]
8. Potent Plasmodium falciparum gametocytocidal activity of diaminonaphthoquinones, lead antimalarial chemotypes identified in an antimalarial compound screen. Tanaka TQ; Guiguemde WA; Barnett DS; Maron MI; Min J; Connelly MC; Suryadevara PK; Guy RK; Williamson KC Antimicrob Agents Chemother; 2015 Mar; 59(3):1389-97. PubMed ID: 25512421 [TBL] [Abstract][Full Text] [Related]
9. Chemoprotective antimalarials identified through quantitative high-throughput screening of Plasmodium blood and liver stage parasites. Dorjsuren D; Eastman RT; Wicht KJ; Jansen D; Talley DC; Sigmon BA; Zakharov AV; Roncal N; Girvin AT; Antonova-Koch Y; Will PM; Shah P; Sun H; Klumpp-Thomas C; Mok S; Yeo T; Meister S; Marugan JJ; Ross LS; Xu X; Maloney DJ; Jadhav A; Mott BT; Sciotti RJ; Winzeler EA; Waters NC; Campbell RF; Huang W; Simeonov A; Fidock DA Sci Rep; 2021 Jan; 11(1):2121. PubMed ID: 33483532 [TBL] [Abstract][Full Text] [Related]
10. Antimalarial agents against both sexual and asexual parasites stages: structure-activity relationships and biological studies of the Malaria Box compound 1-[5-(4-bromo-2-chlorophenyl)furan-2-yl]-N-[(piperidin-4-yl)methyl]methanamine (MMV019918) and analogues. Vallone A; D'Alessandro S; Brogi S; Brindisi M; Chemi G; Alfano G; Lamponi S; Lee SG; Jez JM; Koolen KJM; Dechering KJ; Saponara S; Fusi F; Gorelli B; Taramelli D; Parapini S; Caldelari R; Campiani G; Gemma S; Butini S Eur J Med Chem; 2018 Apr; 150():698-718. PubMed ID: 29571157 [TBL] [Abstract][Full Text] [Related]
11. Antiapicoplast and gametocytocidal screening to identify the mechanisms of action of compounds within the malaria box. Bowman JD; Merino EF; Brooks CF; Striepen B; Carlier PR; Cassera MB Antimicrob Agents Chemother; 2014; 58(2):811-9. PubMed ID: 24247137 [TBL] [Abstract][Full Text] [Related]
12. Design of antimalarial transmission blocking agents: Pharmacophore mapping of ligands active against stage-V mature gametocytes of Aher RB; Roy K J Biomol Struct Dyn; 2019 Sep; 37(14):3660-3673. PubMed ID: 30238847 [TBL] [Abstract][Full Text] [Related]
13. Discovery of HDAC inhibitors with potent activity against multiple malaria parasite life cycle stages. Hansen FK; Sumanadasa SD; Stenzel K; Duffy S; Meister S; Marek L; Schmetter R; Kuna K; Hamacher A; Mordmüller B; Kassack MU; Winzeler EA; Avery VM; Andrews KT; Kurz T Eur J Med Chem; 2014 Jul; 82():204-13. PubMed ID: 24904967 [TBL] [Abstract][Full Text] [Related]
14. Luciferase-Based, High-Throughput Assay for Screening and Profiling Transmission-Blocking Compounds against Plasmodium falciparum Gametocytes. Lucantoni L; Fidock DA; Avery VM Antimicrob Agents Chemother; 2016 Apr; 60(4):2097-107. PubMed ID: 26787698 [TBL] [Abstract][Full Text] [Related]
15. Adapt or Die: Targeting Unique Transmission-Stage Biology for Malaria Elimination. van der Watt ME; Reader J; Birkholtz LM Front Cell Infect Microbiol; 2022; 12():901971. PubMed ID: 35755845 [No Abstract] [Full Text] [Related]
16. Progressing the global antimalarial portfolio: finding drugs which target multiple Plasmodium life stages. Smith PW; Diagana TT; Yeung BK Parasitology; 2014 Jan; 141(1):66-76. PubMed ID: 23746048 [TBL] [Abstract][Full Text] [Related]
17. 4-Nitro styrylquinoline is an antimalarial inhibiting multiple stages of Plasmodium falciparum asexual life cycle. Roberts BF; Zheng Y; Cleaveleand J; Lee S; Lee E; Ayong L; Yuan Y; Chakrabarti D Int J Parasitol Drugs Drug Resist; 2017 Apr; 7(1):120-129. PubMed ID: 28285258 [TBL] [Abstract][Full Text] [Related]
18. Discovery of fast-acting dual-stage antimalarial agents by profiling pyridylvinylquinoline chemical space via copper catalyzed azide-alkyne cycloadditions. Huang G; Solano CM; Melendez J; Yu-Alfonzo S; Boonhok R; Min H; Miao J; Chakrabarti D; Yuan Y Eur J Med Chem; 2021 Jan; 209():112889. PubMed ID: 33045660 [TBL] [Abstract][Full Text] [Related]
19. 3,5-bis(benzylidene)-4-piperidones and related N-acyl analogs: a novel cluster of antimalarials targeting the liver stage of Plasmodium falciparum. Das U; Singh RS; Alcorn J; Hickman MR; Sciotti RJ; Leed SE; Lee PJ; Roncal N; Dimmock JR Bioorg Med Chem; 2013 Dec; 21(23):7250-6. PubMed ID: 24139941 [TBL] [Abstract][Full Text] [Related]
20. Antimalarial drug discovery - the path towards eradication. Burrows JN; Burlot E; Campo B; Cherbuin S; Jeanneret S; Leroy D; Spangenberg T; Waterson D; Wells TN; Willis P Parasitology; 2014 Jan; 141(1):128-39. PubMed ID: 23863111 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]