These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

178 related articles for article (PubMed ID: 33432245)

  • 1. Cryo-EM structures of Toll-like receptors in complex with UNC93B1.
    Ishida H; Asami J; Zhang Z; Nishizawa T; Shigematsu H; Ohto U; Shimizu T
    Nat Struct Mol Biol; 2021 Feb; 28(2):173-180. PubMed ID: 33432245
    [TBL] [Abstract][Full Text] [Related]  

  • 2. UNC93B1 and nucleic acid-sensing Toll-like receptors mediate host resistance to infection with Leishmania major.
    Schamber-Reis BL; Petritus PM; Caetano BC; Martinez ER; Okuda K; Golenbock D; Scott P; Gazzinelli RT
    J Biol Chem; 2013 Mar; 288(10):7127-36. PubMed ID: 23325805
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The Chaperone UNC93B1 Regulates Toll-like Receptor Stability Independently of Endosomal TLR Transport.
    Pelka K; Bertheloot D; Reimer E; Phulphagar K; Schmidt SV; Christ A; Stahl R; Watson N; Miyake K; Hacohen N; Haas A; Brinkmann MM; Marshak-Rothstein A; Meissner F; Latz E
    Immunity; 2018 May; 48(5):911-922.e7. PubMed ID: 29768176
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Acidic amino acid residues in the juxtamembrane region of the nucleotide-sensing TLRs are important for UNC93B1 binding and signaling.
    Kim J; Huh J; Hwang M; Kwon EH; Jung DJ; Brinkmann MM; Jang MH; Ploegh HL; Kim YM
    J Immunol; 2013 May; 190(10):5287-95. PubMed ID: 23585677
    [TBL] [Abstract][Full Text] [Related]  

  • 5. UNC93B1 variants underlie TLR7-dependent autoimmunity.
    Wolf C; Lim EL; Mokhtari M; Kind B; Odainic A; Lara-Villacanas E; Koss S; Mages S; Menzel K; Engel K; Dückers G; Bernbeck B; Schneider DT; Siepermann K; Niehues T; Goetzke CC; Durek P; Minden K; Dörner T; Stittrich A; Szelinski F; Guerra GM; Massoud M; Bieringer M; de Oliveira Mann CC; Beltrán E; Kallinich T; Mashreghi MF; Schmidt SV; Latz E; Klughammer J; Majer O; Lee-Kirsch MA
    Sci Immunol; 2024 Feb; 9(92):eadi9769. PubMed ID: 38207055
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Unc93B1 biases Toll-like receptor responses to nucleic acid in dendritic cells toward DNA- but against RNA-sensing.
    Fukui R; Saitoh S; Matsumoto F; Kozuka-Hata H; Oyama M; Tabeta K; Beutler B; Miyake K
    J Exp Med; 2009 Jun; 206(6):1339-50. PubMed ID: 19451267
    [TBL] [Abstract][Full Text] [Related]  

  • 7. UNC93B1 delivers nucleotide-sensing toll-like receptors to endolysosomes.
    Kim YM; Brinkmann MM; Paquet ME; Ploegh HL
    Nature; 2008 Mar; 452(7184):234-8. PubMed ID: 18305481
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Release from UNC93B1 reinforces the compartmentalized activation of select TLRs.
    Majer O; Liu B; Woo BJ; Kreuk LSM; Van Dis E; Barton GM
    Nature; 2019 Nov; 575(7782):371-374. PubMed ID: 31546247
    [TBL] [Abstract][Full Text] [Related]  

  • 9. UNC93B1 recruits syntenin-1 to dampen TLR7 signalling and prevent autoimmunity.
    Majer O; Liu B; Kreuk LSM; Krogan N; Barton GM
    Nature; 2019 Nov; 575(7782):366-370. PubMed ID: 31546246
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The role of UNC93B1 protein in surface localization of TLR3 receptor and in cell priming to nucleic acid agonists.
    Pohar J; Pirher N; Benčina M; Manček-Keber M; Jerala R
    J Biol Chem; 2013 Jan; 288(1):442-54. PubMed ID: 23166319
    [TBL] [Abstract][Full Text] [Related]  

  • 11. LRRC59 Regulates Trafficking of Nucleic Acid-Sensing TLRs from the Endoplasmic Reticulum via Association with UNC93B1.
    Tatematsu M; Funami K; Ishii N; Seya T; Obuse C; Matsumoto M
    J Immunol; 2015 Nov; 195(10):4933-42. PubMed ID: 26466955
    [TBL] [Abstract][Full Text] [Related]  

  • 12. UNC93B1 mediates differential trafficking of endosomal TLRs.
    Lee BL; Moon JE; Shu JH; Yuan L; Newman ZR; Schekman R; Barton GM
    Elife; 2013 Feb; 2():e00291. PubMed ID: 23426999
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Large-scale mutational analysis identifies UNC93B1 variants that drive TLR-mediated autoimmunity in mice and humans.
    Rael VE; Yano JA; Huizar JP; Slayden LC; Weiss MA; Turcotte EA; Terry JM; Zuo W; Thiffault I; Pastinen T; Farrow EG; Jenkins JL; Becker ML; Wong SC; Stevens AM; Otten C; Allenspach EJ; Bonner DE; Bernstein JA; Wheeler MT; Saxton RA; ; Liu B; Majer O; Barton GM
    J Exp Med; 2024 Aug; 221(8):. PubMed ID: 38780621
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Cutting edge: the UNC93B1 tyrosine-based motif regulates trafficking and TLR responses via separate mechanisms.
    Pelka K; Phulphagar K; Zimmermann J; Stahl R; Schmid-Burgk JL; Schmidt T; Spille JH; Labzin LI; Agrawal S; Kandimalla ER; Casanova JL; Hornung V; Marshak-Rothstein A; Höning S; Latz E
    J Immunol; 2014 Oct; 193(7):3257-61. PubMed ID: 25187660
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Regulatory molecules required for nucleotide-sensing Toll-like receptors.
    Saitoh S; Miyake K
    Immunol Rev; 2009 Jan; 227(1):32-43. PubMed ID: 19120473
    [TBL] [Abstract][Full Text] [Related]  

  • 16. UNC93B1 physically associates with human TLR8 and regulates TLR8-mediated signaling.
    Itoh H; Tatematsu M; Watanabe A; Iwano K; Funami K; Seya T; Matsumoto M
    PLoS One; 2011; 6(12):e28500. PubMed ID: 22164301
    [TBL] [Abstract][Full Text] [Related]  

  • 17. UNC93B1 is essential for the plasma membrane localization and signaling of Toll-like receptor 5.
    Huh JW; Shibata T; Hwang M; Kwon EH; Jang MS; Fukui R; Kanno A; Jung DJ; Jang MH; Miyake K; Kim YM
    Proc Natl Acad Sci U S A; 2014 May; 111(19):7072-7. PubMed ID: 24778236
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Unc93B1 restricts systemic lethal inflammation by orchestrating Toll-like receptor 7 and 9 trafficking.
    Fukui R; Saitoh S; Kanno A; Onji M; Shibata T; Ito A; Onji M; Matsumoto M; Akira S; Yoshida N; Miyake K
    Immunity; 2011 Jul; 35(1):69-81. PubMed ID: 21683627
    [TBL] [Abstract][Full Text] [Related]  

  • 19. N-glycosylation of UNC93B1 at a Specific Asparagine Residue Is Required for TLR9 Signaling.
    Song HS; Park S; Huh JW; Lee YR; Jung DJ; Yang C; Kim SH; Kim HM; Kim YM
    Front Immunol; 2022; 13():875083. PubMed ID: 35874766
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Autophagy downstream of endosomal Toll-like receptor signaling in macrophages is a key mechanism for resistance to
    Franco LH; Fleuri AKA; Pellison NC; Quirino GFS; Horta CV; de Carvalho RVH; Oliveira SC; Zamboni DS
    J Biol Chem; 2017 Aug; 292(32):13087-13096. PubMed ID: 28607148
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.