BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

259 related articles for article (PubMed ID: 33434947)

  • 1. Characterization of cytochrome P450 (CYP) 2D6 drugs as substrates of human organic cation transporters and multidrug and toxin extrusion proteins.
    Neul C; Hofmann U; Schaeffeler E; Winter S; Klein K; Giacomini KM; Eichelbaum M; Schwab M; Nies AT
    Br J Pharmacol; 2021 Mar; 178(6):1459-1474. PubMed ID: 33434947
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Organic cation transporters (OCTs, MATEs), in vitro and in vivo evidence for the importance in drug therapy.
    Nies AT; Koepsell H; Damme K; Schwab M
    Handb Exp Pharmacol; 2011; (201):105-67. PubMed ID: 21103969
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Proguanil and cycloguanil are organic cation transporter and multidrug and toxin extrusion substrates.
    van der Velden M; Bilos A; van den Heuvel JJMW; Rijpma SR; Hurkmans EGE; Sauerwein RW; Russel FGM; Koenderink JB
    Malar J; 2017 Oct; 16(1):422. PubMed ID: 29061131
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Update on drug-drug interaction at organic cation transporters: mechanisms, clinical impact, and proposal for advanced
    Koepsell H
    Expert Opin Drug Metab Toxicol; 2021 Jun; 17(6):635-653. PubMed ID: 33896325
    [No Abstract]   [Full Text] [Related]  

  • 5. Organic cation transporter OCTs (SLC22) and MATEs (SLC47) in the human kidney.
    Motohashi H; Inui K
    AAPS J; 2013 Apr; 15(2):581-8. PubMed ID: 23435786
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Human multidrug and toxin extrusion 1 (MATE1/SLC47A1) transporter: functional characterization, interaction with OCT2 (SLC22A2), and single nucleotide polymorphisms.
    Meyer zu Schwabedissen HE; Verstuyft C; Kroemer HK; Becquemont L; Kim RB
    Am J Physiol Renal Physiol; 2010 Apr; 298(4):F997-F1005. PubMed ID: 20053795
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Double-transfected MDCK cells expressing human OCT1/MATE1 or OCT2/MATE1: determinants of uptake and transcellular translocation of organic cations.
    König J; Zolk O; Singer K; Hoffmann C; Fromm MF
    Br J Pharmacol; 2011 Jun; 163(3):546-55. PubMed ID: 20883471
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The Nonmetabolized β-Blocker Nadolol Is a Substrate of OCT1, OCT2, MATE1, MATE2-K, and P-Glycoprotein, but Not of OATP1B1 and OATP1B3.
    Misaka S; Knop J; Singer K; Hoier E; Keiser M; Müller F; Glaeser H; König J; Fromm MF
    Mol Pharm; 2016 Feb; 13(2):512-9. PubMed ID: 26702643
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Interplay of the Organic Cation Transporters OCT1 and OCT2 with the Apically Localized Export Protein MATE1 for the Polarized Transport of Trospium.
    Deutsch B; Neumeister C; Schwantes U; Fromm MF; König J
    Mol Pharm; 2019 Feb; 16(2):510-517. PubMed ID: 30656943
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Organic cation transporter 3 (OCT3/SLC22A3) and multidrug and toxin extrusion 1 (MATE1/SLC47A1) transporter in the placenta and fetal tissues: expression profile and fetus protective role at different stages of gestation.
    Ahmadimoghaddam D; Zemankova L; Nachtigal P; Dolezelova E; Neumanova Z; Cerveny L; Ceckova M; Kacerovský M; Micuda S; Staud F
    Biol Reprod; 2013 Mar; 88(3):55. PubMed ID: 23303678
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Imatinib Uptake into Cells is Not Mediated by Organic Cation Transporters OCT1, OCT2, or OCT3, But is Influenced by Extracellular pH.
    Blanc Mettral J; Faller N; Cruchon S; Sottas L; Buclin T; Schild L; Choong E; Nahimana A; Decosterd LA
    Drug Metab Lett; 2019; 13(2):102-110. PubMed ID: 30734690
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Characterization of human organic cation transporter 1 (OCT1/SLC22A1)- and OCT2 (SLC22A2)-mediated transport of 1-(2-methoxyethyl)-2-methyl-4,9-dioxo-3-(pyrazin-2-ylmethyl)- 4,9-dihydro-1H-naphtho[2,3-d]imidazolium bromide (YM155 monobromide), a novel small molecule survivin suppressant.
    Minematsu T; Iwai M; Umehara K; Usui T; Kamimura H
    Drug Metab Dispos; 2010 Jan; 38(1):1-4. PubMed ID: 19833842
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Fampridine is a Substrate and Inhibitor of Human OCT2, but not of Human MATE1, or MATE2K.
    Xiao G; Rowbottom C; Boiselle C; Gan LS
    Pharm Res; 2018 Jun; 35(8):159. PubMed ID: 29915999
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The MATE1 rs2289669 polymorphism affects the renal clearance of metformin following ranitidine treatment.
    Cho SK; Chung JY
    Int J Clin Pharmacol Ther; 2016 Apr; 54(4):253-62. PubMed ID: 26784938
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Moxifloxacin Is a Potent In Vitro Inhibitor of OCT- and MATE-Mediated Transport of Metformin and Ethambutol.
    Te Brake LH; van den Heuvel JJ; Buaben AO; van Crevel R; Bilos A; Russel FG; Aarnoutse RE; Koenderink JB
    Antimicrob Agents Chemother; 2016 Dec; 60(12):7105-7114. PubMed ID: 27645247
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Deficiency in the organic cation transporters 1 and 2 (Oct1/Oct2 [Slc22a1/Slc22a2]) in mice abolishes renal secretion of organic cations.
    Jonker JW; Wagenaar E; Van Eijl S; Schinkel AH
    Mol Cell Biol; 2003 Nov; 23(21):7902-8. PubMed ID: 14560032
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Irinotecan Alters the Disposition of Morphine Via Inhibition of Organic Cation Transporter 1 (OCT1) and 2 (OCT2).
    Zhu P; Ye Z; Guo D; Xiong Z; Huang S; Guo J; Zhang W; Polli JE; Zhou H; Li Q; Shu Y
    Pharm Res; 2018 Oct; 35(12):243. PubMed ID: 30361780
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Association of genetic variation in the organic cation transporters OCT1, OCT2 and multidrug and toxin extrusion 1 transporter protein genes with the gastrointestinal side effects and lower BMI in metformin-treated type 2 diabetes patients.
    Tarasova L; Kalnina I; Geldnere K; Bumbure A; Ritenberga R; Nikitina-Zake L; Fridmanis D; Vaivade I; Pirags V; Klovins J
    Pharmacogenet Genomics; 2012 Sep; 22(9):659-66. PubMed ID: 22735389
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Genetic and Epigenetic Regulation of Organic Cation Transporters.
    Kölz C; Schaeffeler E; Schwab M; Nies AT
    Handb Exp Pharmacol; 2021; 266():81-100. PubMed ID: 33674913
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Expression of organic cation transporters OCT1 (SLC22A1) and OCT3 (SLC22A3) is affected by genetic factors and cholestasis in human liver.
    Nies AT; Koepsell H; Winter S; Burk O; Klein K; Kerb R; Zanger UM; Keppler D; Schwab M; Schaeffeler E
    Hepatology; 2009 Oct; 50(4):1227-40. PubMed ID: 19591196
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.