These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

204 related articles for article (PubMed ID: 33438469)

  • 1. New approaches for small molecule-induced protein degradation.
    Wu S; Xiao H; Sun Q
    Future Med Chem; 2021 Mar; 13(5):439-441. PubMed ID: 33438469
    [No Abstract]   [Full Text] [Related]  

  • 2. Targeting the undruggables-the power of protein degraders.
    Zhang C; Liu Y; Li G; Yang Z; Han C; Sun X; Sheng C; Ding K; Rao Y
    Sci Bull (Beijing); 2024 Jun; 69(11):1776-1797. PubMed ID: 38614856
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The arginylation branch of the N-end rule pathway positively regulates cellular autophagic flux and clearance of proteotoxic proteins.
    Jiang Y; Lee J; Lee JH; Lee JW; Kim JH; Choi WH; Yoo YD; Cha-Molstad H; Kim BY; Kwon YT; Noh SA; Kim KP; Lee MJ
    Autophagy; 2016 Nov; 12(11):2197-2212. PubMed ID: 27560450
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Autophagy mediated targeting degradation, a promising strategy in drug development.
    Zhang J; Pan X; Ji W; Zhou J
    Bioorg Chem; 2024 Aug; 149():107466. PubMed ID: 38843684
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Cadmium-induced cytotoxicity in mouse liver cells is associated with the disruption of autophagic flux via inhibiting the fusion of autophagosomes and lysosomes.
    Zou H; Wang T; Yuan J; Sun J; Yuan Y; Gu J; Liu X; Bian J; Liu Z
    Toxicol Lett; 2020 Mar; 321():32-43. PubMed ID: 31862506
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The cholesterol transfer protein GRAMD1A regulates autophagosome biogenesis.
    Laraia L; Friese A; Corkery DP; Konstantinidis G; Erwin N; Hofer W; Karatas H; Klewer L; Brockmeyer A; Metz M; Schölermann B; Dwivedi M; Li L; Rios-Munoz P; Köhn M; Winter R; Vetter IR; Ziegler S; Janning P; Wu YW; Waldmann H
    Nat Chem Biol; 2019 Jul; 15(7):710-720. PubMed ID: 31222192
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Optical control of targeted protein degradation.
    Reynders M; Trauner D
    Cell Chem Biol; 2021 Jul; 28(7):969-986. PubMed ID: 34115971
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Proteolysis targeting chimera (PROTAC) in drug discovery paradigm: Recent progress and future challenges.
    Zeng S; Huang W; Zheng X; Liyan Cheng ; Zhang Z; Wang J; Shen Z
    Eur J Med Chem; 2021 Jan; 210():112981. PubMed ID: 33160761
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Protein degradation technology: a strategic paradigm shift in drug discovery.
    Li H; Dong J; Cai M; Xu Z; Cheng XD; Qin JJ
    J Hematol Oncol; 2021 Sep; 14(1):138. PubMed ID: 34488823
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Challenges and opportunities for
    Benowitz AB; Scott-Stevens PT; Harling JD
    Future Med Chem; 2022 Jan; 14(3):119-121. PubMed ID: 34528453
    [No Abstract]   [Full Text] [Related]  

  • 11. Small-Molecule PROTACS: New Approaches to Protein Degradation.
    Toure M; Crews CM
    Angew Chem Int Ed Engl; 2016 Feb; 55(6):1966-73. PubMed ID: 26756721
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Photopharmacology-based small-molecule proteolysis targeting chimeras: optical control of protein degradation.
    Li W; Elhassan RM; Fang H; Hou X
    Future Med Chem; 2020 Nov; 12(22):1991-1993. PubMed ID: 33054433
    [No Abstract]   [Full Text] [Related]  

  • 13. Quantitative Live-Cell Kinetic Degradation and Mechanistic Profiling of PROTAC Mode of Action.
    Riching KM; Mahan S; Corona CR; McDougall M; Vasta JD; Robers MB; Urh M; Daniels DL
    ACS Chem Biol; 2018 Sep; 13(9):2758-2770. PubMed ID: 30137962
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Targeting Lysosomal Degradation Pathways: New Strategies and Techniques for Drug Discovery.
    Pei J; Wang G; Feng L; Zhang J; Jiang T; Sun Q; Ouyang L
    J Med Chem; 2021 Apr; 64(7):3493-3507. PubMed ID: 33764774
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Recent Advances of Degradation Technologies Based on PROTAC Mechanism.
    Xiao M; Zhao J; Wang Q; Liu J; Ma L
    Biomolecules; 2022 Sep; 12(9):. PubMed ID: 36139095
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The proton pump inhibitor pantoprazole disrupts protein degradation systems and sensitizes cancer cells to death under various stresses.
    Cao Y; Chen M; Tang D; Yan H; Ding X; Zhou F; Zhang M; Xu G; Zhang W; Zhang S; Zhuge Y; Wang L; Zou X
    Cell Death Dis; 2018 May; 9(6):604. PubMed ID: 29789637
    [TBL] [Abstract][Full Text] [Related]  

  • 17. High perfluorooctanoic acid exposure induces autophagy blockage and disturbs intracellular vesicle fusion in the liver.
    Yan S; Zhang H; Guo X; Wang J; Dai J
    Arch Toxicol; 2017 Jan; 91(1):247-258. PubMed ID: 26879310
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Small-molecule regulators of autophagy and their potential therapeutic applications.
    Zhou M; Wang R
    ChemMedChem; 2013 May; 8(5):694-707. PubMed ID: 23568434
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Emerging New Concepts of Degrader Technologies.
    Ding Y; Fei Y; Lu B
    Trends Pharmacol Sci; 2020 Jul; 41(7):464-474. PubMed ID: 32416934
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Targeted protein degradation as a powerful research tool in basic biology and drug target discovery.
    Wu T; Yoon H; Xiong Y; Dixon-Clarke SE; Nowak RP; Fischer ES
    Nat Struct Mol Biol; 2020 Jul; 27(7):605-614. PubMed ID: 32541897
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.