These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

470 related articles for article (PubMed ID: 33445986)

  • 1. A Tale of Two Tails: Efficient Profiling of Protein Degraders by Specific Functional and Target Engagement Readouts.
    Chernobrovkin AL; Cázares-Körner C; Friman T; Caballero IM; Amadio D; Martinez Molina D
    SLAS Discov; 2021 Apr; 26(4):534-546. PubMed ID: 33445986
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Small-Molecule Degraders beyond PROTACs-Challenges and Opportunities.
    Kastl JM; Davies G; Godsman E; Holdgate GA
    SLAS Discov; 2021 Apr; 26(4):524-533. PubMed ID: 33632029
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The Vital Role of Proteomics in Characterizing Novel Protein Degraders.
    Zhang AX; Cassidy K; Dahl G; Moreau K; Pachl F; Zuhl AM
    SLAS Discov; 2021 Apr; 26(4):518-523. PubMed ID: 33615886
    [TBL] [Abstract][Full Text] [Related]  

  • 4. E3 Ligase Ligands for PROTACs: How They Were Found and How to Discover New Ones.
    Ishida T; Ciulli A
    SLAS Discov; 2021 Apr; 26(4):484-502. PubMed ID: 33143537
    [TBL] [Abstract][Full Text] [Related]  

  • 5. High-Throughput Quantitative Assay Technologies for Accelerating the Discovery and Optimization of Targeted Protein Degradation Therapeutics.
    Simard JR; Lee L; Vieux E; Improgo R; Tieu T; Phillips AJ; Fisher SL; Pollock RM; Park E
    SLAS Discov; 2021 Apr; 26(4):503-517. PubMed ID: 33430712
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Target Validation Using PROTACs: Applying the Four Pillars Framework.
    Nowak RP; Jones LH
    SLAS Discov; 2021 Apr; 26(4):474-483. PubMed ID: 33334221
    [TBL] [Abstract][Full Text] [Related]  

  • 7. [Induced degradation of proteins by PROTACs and other strategies: towards promising drugs].
    Reboud-Ravaux M
    Biol Aujourdhui; 2021; 215(1-2):25-43. PubMed ID: 34397373
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Proteolysis targeting chimeras (PROTACs) are emerging therapeutics for hematologic malignancies.
    He Y; Khan S; Huo Z; Lv D; Zhang X; Liu X; Yuan Y; Hromas R; Xu M; Zheng G; Zhou D
    J Hematol Oncol; 2020 Jul; 13(1):103. PubMed ID: 32718354
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Recent advances in targeted protein degraders as potential therapeutic agents.
    Yang N; Kong B; Zhu Z; Huang F; Zhang L; Lu T; Chen Y; Zhang Y; Jiang Y
    Mol Divers; 2024 Feb; 28(1):309-333. PubMed ID: 36790583
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Targeted protein degradation via intramolecular bivalent glues.
    Hsia O; Hinterndorfer M; Cowan AD; Iso K; Ishida T; Sundaramoorthy R; Nakasone MA; Imrichova H; Schätz C; Rukavina A; Husnjak K; Wegner M; Correa-Sáez A; Craigon C; Casement R; Maniaci C; Testa A; Kaulich M; Dikic I; Winter GE; Ciulli A
    Nature; 2024 Mar; 627(8002):204-211. PubMed ID: 38383787
    [TBL] [Abstract][Full Text] [Related]  

  • 11. PROteolysis TArgeting Chimeras (PROTACs) as emerging anticancer therapeutics.
    Khan S; He Y; Zhang X; Yuan Y; Pu S; Kong Q; Zheng G; Zhou D
    Oncogene; 2020 Jun; 39(26):4909-4924. PubMed ID: 32475992
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Characterisation of high throughput screening outputs for small molecule degrader discovery.
    Bell LE; Bardelle C; Packer MJ; Kastl J; Holdgate GA; Davies G
    SLAS Discov; 2024 Jul; 29(5):100162. PubMed ID: 38797285
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The rise of covalent proteolysis targeting chimeras.
    Gabizon R; London N
    Curr Opin Chem Biol; 2021 Jun; 62():24-33. PubMed ID: 33549806
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Targeted protein degradation and the enzymology of degraders.
    Fisher SL; Phillips AJ
    Curr Opin Chem Biol; 2018 Jun; 44():47-55. PubMed ID: 29885948
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Applications of protein ubiquitylation and deubiquitylation in drug discovery.
    Chen Y; Xue H; Jin J
    J Biol Chem; 2024 May; 300(5):107264. PubMed ID: 38582446
    [TBL] [Abstract][Full Text] [Related]  

  • 16. PROTACs: past, present and future.
    Li K; Crews CM
    Chem Soc Rev; 2022 Jun; 51(12):5214-5236. PubMed ID: 35671157
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Small molecule PROTACs in targeted therapy: An emerging strategy to induce protein degradation.
    Xi M; Chen Y; Yang H; Xu H; Du K; Wu C; Xu Y; Deng L; Luo X; Yu L; Wu Y; Gao X; Cai T; Chen B; Shen R; Sun H
    Eur J Med Chem; 2019 Jul; 174():159-180. PubMed ID: 31035238
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Lessons in PROTAC Design from Selective Degradation with a Promiscuous Warhead.
    Bondeson DP; Smith BE; Burslem GM; Buhimschi AD; Hines J; Jaime-Figueroa S; Wang J; Hamman BD; Ishchenko A; Crews CM
    Cell Chem Biol; 2018 Jan; 25(1):78-87.e5. PubMed ID: 29129718
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Preclinical Studies of PROTACs in Hematological Malignancies.
    Fuchs O; Bokorova R
    Cardiovasc Hematol Disord Drug Targets; 2021; 21(1):7-22. PubMed ID: 33687890
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Molecular Glues: The Adhesive Connecting Targeted Protein Degradation to the Clinic.
    Sasso JM; Tenchov R; Wang D; Johnson LS; Wang X; Zhou QA
    Biochemistry; 2023 Feb; 62(3):601-623. PubMed ID: 35856839
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 24.