These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

168 related articles for article (PubMed ID: 33446037)

  • 1. Inhibition of nucleophosmin 1 suppresses colorectal cancer tumor growth of patient -derived xenografts via activation of p53 and inhibition of AKT.
    Yu ACY; Chern YJ; Zhang P; Pasiliao CC; Rahman M; Chang G; Ren J; Tai IT
    Cancer Biol Ther; 2021 Feb; 22(2):112-123. PubMed ID: 33446037
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Nucleophosmin 1, upregulated in adenomas and cancers of the colon, inhibits p53-mediated cellular senescence.
    Wong JC; Hasan MR; Rahman M; Yu AC; Chan SK; Schaeffer DF; Kennecke HF; Lim HJ; Owen D; Tai IT
    Int J Cancer; 2013 Oct; 133(7):1567-77. PubMed ID: 23536448
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Inhibition of APE1-endonuclease activity affects cell metabolism in colon cancer cells via a p53-dependent pathway.
    Codrich M; Comelli M; Malfatti MC; Mio C; Ayyildiz D; Zhang C; Kelley MR; Terrosu G; Pucillo CEM; Tell G
    DNA Repair (Amst); 2019 Oct; 82():102675. PubMed ID: 31450087
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Targeting AKT with costunolide suppresses the growth of colorectal cancer cells and induces apoptosis in vitro and in vivo.
    Huang H; Park S; Zhang H; Park S; Kwon W; Kim E; Zhang X; Jang S; Yoon D; Choi SK; Yi JK; Kim SH; Dong Z; Lee MH; Ryoo Z; Kim MO
    J Exp Clin Cancer Res; 2021 Mar; 40(1):114. PubMed ID: 33785035
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Targeting NPM1 inhibits proliferation and promotes apoptosis of hepatic progenitor cells via suppression of mTOR signalling pathway.
    Wang P; Wang M; Liu L; Li H; Liu H; Ren J; Liu T; Cong M; Zhu Z; Zhao X; Sun L; Jia J
    Stem Cell Res Ther; 2024 Sep; 15(1):292. PubMed ID: 39256792
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Loss of Smad4 in colorectal cancer induces resistance to 5-fluorouracil through activating Akt pathway.
    Zhang B; Zhang B; Chen X; Bae S; Singh K; Washington MK; Datta PK
    Br J Cancer; 2014 Feb; 110(4):946-57. PubMed ID: 24384683
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Upregulation of microRNA-135b and microRNA-182 promotes chemoresistance of colorectal cancer by targeting ST6GALNAC2 via PI3K/AKT pathway.
    Liu B; Liu Y; Zhao L; Pan Y; Shan Y; Li Y; Jia L
    Mol Carcinog; 2017 Dec; 56(12):2669-2680. PubMed ID: 28767179
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Tumor suppressor LHPP regulates the proliferation of colorectal cancer cells via the PI3K/AKT pathway.
    Hou B; Li W; Li J; Ma J; Xia P; Liu Z; Zeng Q; Zhang X; Chang D
    Oncol Rep; 2020 Feb; 43(2):536-548. PubMed ID: 31894339
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Smad4 sensitizes colorectal cancer to 5-fluorouracil through cell cycle arrest by inhibiting the PI3K/Akt/CDC2/survivin cascade.
    Zhang B; Leng C; Wu C; Zhang Z; Dou L; Luo X; Zhang B; Chen X
    Oncol Rep; 2016 Mar; 35(3):1807-15. PubMed ID: 26647806
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Imidazoquinoxaline derivative EAPB0503: A promising drug targeting mutant nucleophosmin 1 in acute myeloid leukemia.
    Nabbouh AI; Hleihel RS; Saliba JL; Karam MM; Hamie MH; Wu HJM; Berthier CP; Tawil NM; Bonnet PA; Deleuze-Masquefa C; El Hajj HA
    Cancer; 2017 May; 123(9):1662-1673. PubMed ID: 28055106
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Long noncoding RNA SNHG14 accelerates cell proliferation, migration, invasion and suppresses apoptosis in colorectal cancer cells by targeting miR-944/KRAS axis through PI3K/AKT pathway.
    Pei Q; Liu GS; Li HP; Zhang Y; Xu XC; Gao H; Zhang W; Li T
    Eur Rev Med Pharmacol Sci; 2019 Nov; 23(22):9871-9881. PubMed ID: 31799655
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Selective β2-AR Blockage Suppresses Colorectal Cancer Growth Through Regulation of EGFR-Akt/ERK1/2 Signaling, G1-Phase Arrest, and Apoptosis.
    Chin CC; Li JM; Lee KF; Huang YC; Wang KC; Lai HC; Cheng CC; Kuo YH; Shi CS
    J Cell Physiol; 2016 Feb; 231(2):459-72. PubMed ID: 26189563
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Puf-A promotes cancer progression by interacting with nucleophosmin in nucleolus.
    Cho HC; Huang Y; Hung JT; Hung TH; Cheng KC; Liu YH; Kuo MW; Wang SH; Yu AL; Yu J
    Oncogene; 2022 Feb; 41(8):1155-1165. PubMed ID: 34999733
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Selective AKT Inhibition by MK-2206 Represses Colorectal Cancer-Initiating Stem Cells.
    Malkomes P; Lunger I; Luetticke A; Oppermann E; Haetscher N; Serve H; Holzer K; Bechstein WO; Rieger MA
    Ann Surg Oncol; 2016 Sep; 23(9):2849-57. PubMed ID: 27059026
    [TBL] [Abstract][Full Text] [Related]  

  • 15. MDM2 inhibition is synthetic lethal with PTEN loss in colorectal cancer cells via the p53-dependent mechanism.
    Ren G; Yang EJ; Tao S; Mou PK; Pu Y; Chen LJ; Shim JS
    Int J Biol Sci; 2023; 19(11):3544-3557. PubMed ID: 37496993
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Atractylenolide I inhibits colorectal cancer cell proliferation by affecting metabolism and stemness via AKT/mTOR signaling.
    Wang K; Huang W; Sang X; Wu X; Shan Q; Tang D; Xu X; Cao G
    Phytomedicine; 2020 Mar; 68():153191. PubMed ID: 32135457
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Withaferin-A suppress AKT induced tumor growth in colorectal cancer cells.
    Suman S; Das TP; Sirimulla S; Alatassi H; Ankem MK; Damodaran C
    Oncotarget; 2016 Mar; 7(12):13854-64. PubMed ID: 26883103
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Combined application of anti-VEGF and anti-EGFR attenuates the growth and angiogenesis of colorectal cancer mainly through suppressing AKT and ERK signaling in mice model.
    Ding C; Li L; Yang T; Fan X; Wu G
    BMC Cancer; 2016 Oct; 16(1):791. PubMed ID: 27729020
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Desmocollin 3 has a tumor suppressive activity through inhibition of AKT pathway in colorectal cancer.
    Cui T; Yang L; Ma Y; Petersen I; Chen Y
    Exp Cell Res; 2019 May; 378(2):124-130. PubMed ID: 30857973
    [TBL] [Abstract][Full Text] [Related]  

  • 20. PP9, a steroidal saponin, induces G2/M arrest and apoptosis in human colorectal cancer cells by inhibiting the PI3K/Akt/GSK3β pathway.
    Yao M; Li R; Yang Z; Ding Y; Zhang W; Li W; Liu M; Zhao C; Wang Y; Tang H; Wang J; Wen A
    Chem Biol Interact; 2020 Nov; 331():109246. PubMed ID: 32877639
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.