BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

170 related articles for article (PubMed ID: 33446037)

  • 1. Inhibition of nucleophosmin 1 suppresses colorectal cancer tumor growth of patient -derived xenografts via activation of p53 and inhibition of AKT.
    Yu ACY; Chern YJ; Zhang P; Pasiliao CC; Rahman M; Chang G; Ren J; Tai IT
    Cancer Biol Ther; 2021 Feb; 22(2):112-123. PubMed ID: 33446037
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Nucleophosmin 1, upregulated in adenomas and cancers of the colon, inhibits p53-mediated cellular senescence.
    Wong JC; Hasan MR; Rahman M; Yu AC; Chan SK; Schaeffer DF; Kennecke HF; Lim HJ; Owen D; Tai IT
    Int J Cancer; 2013 Oct; 133(7):1567-77. PubMed ID: 23536448
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Targeting AKT with costunolide suppresses the growth of colorectal cancer cells and induces apoptosis in vitro and in vivo.
    Huang H; Park S; Zhang H; Park S; Kwon W; Kim E; Zhang X; Jang S; Yoon D; Choi SK; Yi JK; Kim SH; Dong Z; Lee MH; Ryoo Z; Kim MO
    J Exp Clin Cancer Res; 2021 Mar; 40(1):114. PubMed ID: 33785035
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Loss of Smad4 in colorectal cancer induces resistance to 5-fluorouracil through activating Akt pathway.
    Zhang B; Zhang B; Chen X; Bae S; Singh K; Washington MK; Datta PK
    Br J Cancer; 2014 Feb; 110(4):946-57. PubMed ID: 24384683
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Upregulation of microRNA-135b and microRNA-182 promotes chemoresistance of colorectal cancer by targeting ST6GALNAC2 via PI3K/AKT pathway.
    Liu B; Liu Y; Zhao L; Pan Y; Shan Y; Li Y; Jia L
    Mol Carcinog; 2017 Dec; 56(12):2669-2680. PubMed ID: 28767179
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Tumor suppressor LHPP regulates the proliferation of colorectal cancer cells via the PI3K/AKT pathway.
    Hou B; Li W; Li J; Ma J; Xia P; Liu Z; Zeng Q; Zhang X; Chang D
    Oncol Rep; 2020 Feb; 43(2):536-548. PubMed ID: 31894339
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Smad4 sensitizes colorectal cancer to 5-fluorouracil through cell cycle arrest by inhibiting the PI3K/Akt/CDC2/survivin cascade.
    Zhang B; Leng C; Wu C; Zhang Z; Dou L; Luo X; Zhang B; Chen X
    Oncol Rep; 2016 Mar; 35(3):1807-15. PubMed ID: 26647806
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Imidazoquinoxaline derivative EAPB0503: A promising drug targeting mutant nucleophosmin 1 in acute myeloid leukemia.
    Nabbouh AI; Hleihel RS; Saliba JL; Karam MM; Hamie MH; Wu HJM; Berthier CP; Tawil NM; Bonnet PA; Deleuze-Masquefa C; El Hajj HA
    Cancer; 2017 May; 123(9):1662-1673. PubMed ID: 28055106
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Long noncoding RNA SNHG14 accelerates cell proliferation, migration, invasion and suppresses apoptosis in colorectal cancer cells by targeting miR-944/KRAS axis through PI3K/AKT pathway.
    Pei Q; Liu GS; Li HP; Zhang Y; Xu XC; Gao H; Zhang W; Li T
    Eur Rev Med Pharmacol Sci; 2019 Nov; 23(22):9871-9881. PubMed ID: 31799655
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Inhibition of APE1-endonuclease activity affects cell metabolism in colon cancer cells via a p53-dependent pathway.
    Codrich M; Comelli M; Malfatti MC; Mio C; Ayyildiz D; Zhang C; Kelley MR; Terrosu G; Pucillo CEM; Tell G
    DNA Repair (Amst); 2019 Oct; 82():102675. PubMed ID: 31450087
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Selective β2-AR Blockage Suppresses Colorectal Cancer Growth Through Regulation of EGFR-Akt/ERK1/2 Signaling, G1-Phase Arrest, and Apoptosis.
    Chin CC; Li JM; Lee KF; Huang YC; Wang KC; Lai HC; Cheng CC; Kuo YH; Shi CS
    J Cell Physiol; 2016 Feb; 231(2):459-72. PubMed ID: 26189563
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Selective AKT Inhibition by MK-2206 Represses Colorectal Cancer-Initiating Stem Cells.
    Malkomes P; Lunger I; Luetticke A; Oppermann E; Haetscher N; Serve H; Holzer K; Bechstein WO; Rieger MA
    Ann Surg Oncol; 2016 Sep; 23(9):2849-57. PubMed ID: 27059026
    [TBL] [Abstract][Full Text] [Related]  

  • 13. MDM2 inhibition is synthetic lethal with PTEN loss in colorectal cancer cells via the p53-dependent mechanism.
    Ren G; Yang EJ; Tao S; Mou PK; Pu Y; Chen LJ; Shim JS
    Int J Biol Sci; 2023; 19(11):3544-3557. PubMed ID: 37496993
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Atractylenolide I inhibits colorectal cancer cell proliferation by affecting metabolism and stemness via AKT/mTOR signaling.
    Wang K; Huang W; Sang X; Wu X; Shan Q; Tang D; Xu X; Cao G
    Phytomedicine; 2020 Mar; 68():153191. PubMed ID: 32135457
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Withaferin-A suppress AKT induced tumor growth in colorectal cancer cells.
    Suman S; Das TP; Sirimulla S; Alatassi H; Ankem MK; Damodaran C
    Oncotarget; 2016 Mar; 7(12):13854-64. PubMed ID: 26883103
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Combined application of anti-VEGF and anti-EGFR attenuates the growth and angiogenesis of colorectal cancer mainly through suppressing AKT and ERK signaling in mice model.
    Ding C; Li L; Yang T; Fan X; Wu G
    BMC Cancer; 2016 Oct; 16(1):791. PubMed ID: 27729020
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Desmocollin 3 has a tumor suppressive activity through inhibition of AKT pathway in colorectal cancer.
    Cui T; Yang L; Ma Y; Petersen I; Chen Y
    Exp Cell Res; 2019 May; 378(2):124-130. PubMed ID: 30857973
    [TBL] [Abstract][Full Text] [Related]  

  • 18. BCL6B suppresses proliferation and migration of colorectal carcinoma cells through inhibition of the PI3K/AKT signaling pathway.
    Gu Y; Li A; Sun H; Li X; Zha H; Zhao J; Xie J; Zeng Z; Zhou L
    Int J Mol Med; 2018 May; 41(5):2660-2668. PubMed ID: 29393377
    [TBL] [Abstract][Full Text] [Related]  

  • 19. PP9, a steroidal saponin, induces G2/M arrest and apoptosis in human colorectal cancer cells by inhibiting the PI3K/Akt/GSK3β pathway.
    Yao M; Li R; Yang Z; Ding Y; Zhang W; Li W; Liu M; Zhao C; Wang Y; Tang H; Wang J; Wen A
    Chem Biol Interact; 2020 Nov; 331():109246. PubMed ID: 32877639
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The tumor-suppressor gene LZTS1 suppresses colorectal cancer proliferation through inhibition of the AKT-mTOR signaling pathway.
    Zhou W; He MR; Jiao HL; He LQ; Deng DL; Cai JJ; Xiao ZY; Ye YP; Ding YQ; Liao WT; Liu SD
    Cancer Lett; 2015 Apr; 360(1):68-75. PubMed ID: 25667121
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.