217 related articles for article (PubMed ID: 33446805)
1. SHP2 blockade enhances anti-tumor immunity via tumor cell intrinsic and extrinsic mechanisms.
Wang Y; Mohseni M; Grauel A; Diez JE; Guan W; Liang S; Choi JE; Pu M; Chen D; Laszewski T; Schwartz S; Gu J; Mansur L; Burks T; Brodeur L; Velazquez R; Kovats S; Pant B; Buruzula G; Deng E; Chen JT; Sari-Sarraf F; Dornelas C; Varadarajan M; Yu H; Liu C; Lim J; Hao HX; Jiang X; Malamas A; LaMarche MJ; Geyer FC; McLaughlin M; Costa C; Wagner J; Ruddy D; Jayaraman P; Kirkpatrick ND; Zhang P; Iartchouk O; Aardalen K; Cremasco V; Dranoff G; Engelman JA; Silver S; Wang H; Hastings WD; Goldoni S
Sci Rep; 2021 Jan; 11(1):1399. PubMed ID: 33446805
[TBL] [Abstract][Full Text] [Related]
2. Allosteric Inhibition of SHP2 Stimulates Antitumor Immunity by Transforming the Immunosuppressive Environment.
Quintana E; Schulze CJ; Myers DR; Choy TJ; Mordec K; Wildes D; Shifrin NT; Belwafa A; Koltun ES; Gill AL; Singh M; Kelsey S; Goldsmith MA; Nichols R; Smith JAM
Cancer Res; 2020 Jul; 80(13):2889-2902. PubMed ID: 32350067
[TBL] [Abstract][Full Text] [Related]
3. cGAS/STING axis mediates a topoisomerase II inhibitor-induced tumor immunogenicity.
Wang Z; Chen J; Hu J; Zhang H; Xu F; He W; Wang X; Li M; Lu W; Zeng G; Zhou P; Huang P; Chen S; Li W; Xia LP; Xia X
J Clin Invest; 2019 Aug; 129(11):4850-4862. PubMed ID: 31408442
[TBL] [Abstract][Full Text] [Related]
4. Targeting SHP2 as a promising strategy for cancer immunotherapy.
Liu Q; Qu J; Zhao M; Xu Q; Sun Y
Pharmacol Res; 2020 Feb; 152():104595. PubMed ID: 31838080
[TBL] [Abstract][Full Text] [Related]
5. PD-1 and BTLA regulate T cell signaling differentially and only partially through SHP1 and SHP2.
Xu X; Hou B; Fulzele A; Masubuchi T; Zhao Y; Wu Z; Hu Y; Jiang Y; Ma Y; Wang H; Bennett EJ; Fu G; Hui E
J Cell Biol; 2020 Jun; 219(6):. PubMed ID: 32437509
[TBL] [Abstract][Full Text] [Related]
6. Tumor Cell-Autonomous SHP2 Contributes to Immune Suppression in Metastatic Breast Cancer.
Chen H; Cresswell GM; Libring S; Ayers MG; Miao J; Zhang ZY; Solorio L; Ratliff TL; Wendt MK
Cancer Res Commun; 2022 Oct; 2(10):1104-1118. PubMed ID: 36969745
[TBL] [Abstract][Full Text] [Related]
7. Phosphatase Shp2 exacerbates intestinal inflammation by disrupting macrophage responsiveness to interleukin-10.
Xiao P; Zhang H; Zhang Y; Zheng M; Liu R; Zhao Y; Zhang X; Cheng H; Cao Q; Ke Y
J Exp Med; 2019 Feb; 216(2):337-349. PubMed ID: 30610104
[TBL] [Abstract][Full Text] [Related]
8. Myeloid-specific disruption of tyrosine phosphatase Shp2 promotes alternative activation of macrophages and predisposes mice to pulmonary fibrosis.
Tao B; Jin W; Xu J; Liang Z; Yao J; Zhang Y; Wang K; Cheng H; Zhang X; Ke Y
J Immunol; 2014 Sep; 193(6):2801-11. PubMed ID: 25127857
[TBL] [Abstract][Full Text] [Related]
9. ILT4 inhibition prevents TAM- and dysfunctional T cell-mediated immunosuppression and enhances the efficacy of anti-PD-L1 therapy in NSCLC with EGFR activation.
Chen X; Gao A; Zhang F; Yang Z; Wang S; Fang Y; Li J; Wang J; Shi W; Wang L; Zheng Y; Sun Y
Theranostics; 2021; 11(7):3392-3416. PubMed ID: 33537094
[No Abstract] [Full Text] [Related]
10. Intrinsic Expression of Immune Checkpoint Molecule TIGIT Could Help Tumor Growth
Zhou XM; Li WQ; Wu YH; Han L; Cao XG; Yang XM; Wang HF; Zhao WS; Zhai WJ; Qi YM; Gao YF
Front Immunol; 2018; 9():2821. PubMed ID: 30555485
[TBL] [Abstract][Full Text] [Related]
11. Allosteric inhibition of SHP2 phosphatase inhibits cancers driven by receptor tyrosine kinases.
Chen YN; LaMarche MJ; Chan HM; Fekkes P; Garcia-Fortanet J; Acker MG; Antonakos B; Chen CH; Chen Z; Cooke VG; Dobson JR; Deng Z; Fei F; Firestone B; Fodor M; Fridrich C; Gao H; Grunenfelder D; Hao HX; Jacob J; Ho S; Hsiao K; Kang ZB; Karki R; Kato M; Larrow J; La Bonte LR; Lenoir F; Liu G; Liu S; Majumdar D; Meyer MJ; Palermo M; Perez L; Pu M; Price E; Quinn C; Shakya S; Shultz MD; Slisz J; Venkatesan K; Wang P; Warmuth M; Williams S; Yang G; Yuan J; Zhang JH; Zhu P; Ramsey T; Keen NJ; Sellers WR; Stams T; Fortin PD
Nature; 2016 Jul; 535(7610):148-52. PubMed ID: 27362227
[TBL] [Abstract][Full Text] [Related]
12. Atractylenolide I enhances responsiveness to immune checkpoint blockade therapy by activating tumor antigen presentation.
Xu H; Van der Jeught K; Zhou Z; Zhang L; Yu T; Sun Y; Li Y; Wan C; So KM; Liu D; Frieden M; Fang Y; Mosley AL; He X; Zhang X; Sandusky GE; Liu Y; Meroueh SO; Zhang C; Wijeratne AB; Huang C; Ji G; Lu X
J Clin Invest; 2021 May; 131(10):. PubMed ID: 33830945
[TBL] [Abstract][Full Text] [Related]
13. Shp2 deletion in hepatocytes suppresses hepatocarcinogenesis driven by oncogenic β-Catenin, PIK3CA and MET.
Liu JJ; Li Y; Chen WS; Liang Y; Wang G; Zong M; Kaneko K; Xu R; Karin M; Feng GS
J Hepatol; 2018 Jul; 69(1):79-88. PubMed ID: 29505847
[TBL] [Abstract][Full Text] [Related]
14. Blockage of Core Fucosylation Reduces Cell-Surface Expression of PD-1 and Promotes Anti-tumor Immune Responses of T Cells.
Okada M; Chikuma S; Kondo T; Hibino S; Machiyama H; Yokosuka T; Nakano M; Yoshimura A
Cell Rep; 2017 Aug; 20(5):1017-1028. PubMed ID: 28768188
[TBL] [Abstract][Full Text] [Related]
15. SHP2 inhibition triggers anti-tumor immunity and synergizes with PD-1 blockade.
Zhao M; Guo W; Wu Y; Yang C; Zhong L; Deng G; Zhu Y; Liu W; Gu Y; Lu Y; Kong L; Meng X; Xu Q; Sun Y
Acta Pharm Sin B; 2019 Mar; 9(2):304-315. PubMed ID: 30972278
[TBL] [Abstract][Full Text] [Related]
16. The src homology 2 domain-containing tyrosine phosphatase 2 regulates primary T-dependent immune responses and Th cell differentiation.
Salmond RJ; Huyer G; Kotsoni A; Clements L; Alexander DR
J Immunol; 2005 Nov; 175(10):6498-508. PubMed ID: 16272304
[TBL] [Abstract][Full Text] [Related]
17. ROS1 Fusion Mediates Immunogenicity by Upregulation of PD-L1 After the Activation of ROS1-SHP2 Signaling Pathway in Non-Small Cell Lung Cancer.
Cai L; Duan J; Qian L; Wang Z; Wang S; Li S; Wang C; Zhao J; Zhang X; Bai H; Wang J
Front Immunol; 2020; 11():527750. PubMed ID: 33324391
[TBL] [Abstract][Full Text] [Related]
18. Identification, recombinant expression and immunological study of Lja-SHP2 in Lampetra japonica.
Li X; Qu CM; Han YL; Liu X; Li QW
Yi Chuan; 2020 Feb; 42(2):183-193. PubMed ID: 32102775
[TBL] [Abstract][Full Text] [Related]
19. TNF-alpha induces tyrosine phosphorylation and recruitment of the Src homology protein-tyrosine phosphatase 2 to the gp130 signal-transducing subunit of the IL-6 receptor complex.
Bode JG; Schweigart J; Kehrmann J; Ehlting C; Schaper F; Heinrich PC; Häussinger D
J Immunol; 2003 Jul; 171(1):257-66. PubMed ID: 12817006
[TBL] [Abstract][Full Text] [Related]
20. Allosteric Inhibitors of SHP2 with Therapeutic Potential for Cancer Treatment.
Xie J; Si X; Gu S; Wang M; Shen J; Li H; Shen J; Li D; Fang Y; Liu C; Zhu J
J Med Chem; 2017 Dec; 60(24):10205-10219. PubMed ID: 29155585
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]