BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

171 related articles for article (PubMed ID: 33450231)

  • 1. Decreases in different Dnmt3b activities drive distinct development of hematologic malignancies in mice.
    Lopusna K; Nowialis P; Opavska J; Abraham A; Riva A; Haney SL; Opavsky R
    J Biol Chem; 2021; 296():100285. PubMed ID: 33450231
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Methylation-independent repression of Dnmt3b contributes to oncogenic activity of Dnmt3a in mouse MYC-induced T-cell lymphomagenesis.
    Haney SL; Hlady RA; Opavska J; Klinkebiel D; Pirruccello SJ; Dutta S; Datta K; Simpson MA; Wu L; Opavsky R
    Oncogene; 2015 Oct; 34(43):5436-5446. PubMed ID: 25639876
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Dnmt3b catalytic activity is critical for its tumour suppressor function in lymphomagenesis and is associated with c-Met oncogenic signalling.
    Lopusna K; Nowialis P; Opavska J; Abraham A; Riva A; Opavsky R
    EBioMedicine; 2021 Jan; 63():103191. PubMed ID: 33418509
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Loss of Dnmt3b function upregulates the tumor modifier Ment and accelerates mouse lymphomagenesis.
    Hlady RA; Novakova S; Opavska J; Klinkebiel D; Peters SL; Bies J; Hannah J; Iqbal J; Anderson KM; Siebler HM; Smith LM; Greiner TC; Bastola D; Joshi S; Lockridge O; Simpson MA; Felsher DW; Wagner KU; Chan WC; Christman JK; Opavsky R
    J Clin Invest; 2012 Jan; 122(1):163-77. PubMed ID: 22133874
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Paradoxical association of TET loss of function with genome-wide DNA hypomethylation.
    López-Moyado IF; Tsagaratou A; Yuita H; Seo H; Delatte B; Heinz S; Benner C; Rao A
    Proc Natl Acad Sci U S A; 2019 Aug; 116(34):16933-16942. PubMed ID: 31371502
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Essential role for Dnmt1 in the prevention and maintenance of MYC-induced T-cell lymphomas.
    Peters SL; Hlady RA; Opavska J; Klinkebiel D; Novakova S; Smith LM; Lewis RE; Karpf AR; Simpson MA; Wu L; Opavsky R
    Mol Cell Biol; 2013 Nov; 33(21):4321-33. PubMed ID: 24001767
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Expression analysis of the epigenetic methyltransferases and methyl-CpG binding protein families in the normal B-cell and B-cell chronic lymphocytic leukemia (CLL).
    Kn H; Bassal S; Tikellis C; El-Osta A
    Cancer Biol Ther; 2004 Oct; 3(10):989-94. PubMed ID: 15467427
    [TBL] [Abstract][Full Text] [Related]  

  • 8. DNA methyltransferases in hematological malignancies.
    Hoang NM; Rui L
    J Genet Genomics; 2020 Jul; 47(7):361-372. PubMed ID: 32994141
    [TBL] [Abstract][Full Text] [Related]  

  • 9. DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development.
    Okano M; Bell DW; Haber DA; Li E
    Cell; 1999 Oct; 99(3):247-57. PubMed ID: 10555141
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Expression of DNA methyltransferases DNMT1, 3A, and 3B in normal hematopoiesis and in acute and chronic myelogenous leukemia.
    Mizuno S; Chijiwa T; Okamura T; Akashi K; Fukumaki Y; Niho Y; Sasaki H
    Blood; 2001 Mar; 97(5):1172-9. PubMed ID: 11222358
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Catalytically inactive Dnmt3b rescues mouse embryonic development by accessory and repressive functions.
    Nowialis P; Lopusna K; Opavska J; Haney SL; Abraham A; Sheng P; Riva A; Natarajan A; Guryanova O; Simpson M; Hlady R; Xie M; Opavsky R
    Nat Commun; 2019 Sep; 10(1):4374. PubMed ID: 31558711
    [TBL] [Abstract][Full Text] [Related]  

  • 12. DNMT1 and DNMT3B modulate distinct polycomb-mediated histone modifications in colon cancer.
    Jin B; Yao B; Li JL; Fields CR; Delmas AL; Liu C; Robertson KD
    Cancer Res; 2009 Sep; 69(18):7412-21. PubMed ID: 19723660
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Kaempferol Modulates DNA Methylation and Downregulates DNMT3B in Bladder Cancer.
    Qiu W; Lin J; Zhu Y; Zhang J; Zeng L; Su M; Tian Y
    Cell Physiol Biochem; 2017; 41(4):1325-1335. PubMed ID: 28278502
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The inactive Dnmt3b3 isoform preferentially enhances Dnmt3b-mediated DNA methylation.
    Zeng Y; Ren R; Kaur G; Hardikar S; Ying Z; Babcock L; Gupta E; Zhang X; Chen T; Cheng X
    Genes Dev; 2020 Nov; 34(21-22):1546-1558. PubMed ID: 33004415
    [TBL] [Abstract][Full Text] [Related]  

  • 15. DNMT3B isoforms without catalytic activity stimulate gene body methylation as accessory proteins in somatic cells.
    Duymich CE; Charlet J; Yang X; Jones PA; Liang G
    Nat Commun; 2016 Apr; 7():11453. PubMed ID: 27121154
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Dnmt3b is a haploinsufficient tumor suppressor gene in Myc-induced lymphomagenesis.
    Vasanthakumar A; Lepore JB; Zegarek MH; Kocherginsky M; Singh M; Davis EM; Link PA; Anastasi J; Le Beau MM; Karpf AR; Godley LA
    Blood; 2013 Mar; 121(11):2059-63. PubMed ID: 23315164
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Loss of Dnmt3b accelerates MLL-AF9 leukemia progression.
    Zheng Y; Zhang H; Wang Y; Li X; Lu P; Dong F; Pang Y; Ma S; Cheng H; Hao S; Tang F; Yuan W; Zhang X; Cheng T
    Leukemia; 2016 Dec; 30(12):2373-2384. PubMed ID: 27133822
    [TBL] [Abstract][Full Text] [Related]  

  • 18. DNMT3B7, a truncated DNMT3B isoform expressed in human tumors, disrupts embryonic development and accelerates lymphomagenesis.
    Shah MY; Vasanthakumar A; Barnes NY; Figueroa ME; Kamp A; Hendrick C; Ostler KR; Davis EM; Lin S; Anastasi J; Le Beau MM; Moskowitz IP; Melnick A; Pytel P; Godley LA
    Cancer Res; 2010 Jul; 70(14):5840-50. PubMed ID: 20587527
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Expression changes in EZH2, but not in BMI-1, SIRT1, DNMT1 or DNMT3B are associated with DNA methylation changes in prostate cancer.
    Hoffmann MJ; Engers R; Florl AR; Otte AP; Muller M; Schulz WA
    Cancer Biol Ther; 2007 Sep; 6(9):1403-12. PubMed ID: 18637271
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Promoter Hypomethylation and Expression Is Conserved in Mouse Chronic Lymphocytic Leukemia Induced by Decreased or Inactivated Dnmt3a.
    Haney SL; Upchurch GM; Opavska J; Klinkebiel D; Hlady RA; Suresh A; Pirruccello SJ; Shukla V; Lu R; Costinean S; Rizzino A; Karpf AR; Joshi S; Swanson P; Opavsky R
    Cell Rep; 2016 May; 15(6):1190-201. PubMed ID: 27134162
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.