Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

226 related articles for article (PubMed ID: 33450878)

  • 1. Berberine Inhibits Telomerase Activity and Induces Cell Cycle Arrest and Telomere Erosion in Colorectal Cancer Cell Line, HCT 116.
    Samad MA; Saiman MZ; Abdul Majid N; Karsani SA; Yaacob JS
    Molecules; 2021 Jan; 26(2):. PubMed ID: 33450878
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Berberine and RNAi-Targeting Telomerase Reverse Transcriptase (TERT) and/or Telomerase RNA Component (TERC) Caused Oxidation in Colorectal Cancer Cell Line, HCT 116: An Integrative Approach using Molecular and Metabolomic Studies.
    Samad MA; Saiman MZ; Abdul Majid N; Karsani SA; Yaacob JS
    Cell Biochem Biophys; 2024 Mar; 82(1):153-173. PubMed ID: 38198024
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Short-term inhibition of TERT induces telomere length-independent cell cycle arrest and apoptotic response in EBV-immortalized and transformed B cells.
    Celeghin A; Giunco S; Freguja R; Zangrossi M; Nalio S; Dolcetti R; De Rossi A
    Cell Death Dis; 2016 Dec; 7(12):e2562. PubMed ID: 28032863
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Two telomerase-targeting Pt(ii) complexes of jatrorrhizine and berberine derivatives induce apoptosis in human bladder tumor cells.
    Qin QP; Wang ZF; Huang XL; Tan MX; Luo ZH; Wang SL; Zou BQ; Liang H
    Dalton Trans; 2019 Oct; 48(40):15247-15254. PubMed ID: 31577283
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Acquired cellular resistance to flavopiridol in a human colon carcinoma cell line involves up-regulation of the telomerase catalytic subunit and telomere elongation. Sensitivity of resistant cells to combination treatment with a telomerase inhibitor.
    Incles CM; Schultes CM; Kelland LR; Neidle S
    Mol Pharmacol; 2003 Nov; 64(5):1101-8. PubMed ID: 14573759
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Mechanisms of the Antiproliferative and Antitumor Activity of Novel Telomerase-Carbonic Anhydrase Dual-Hybrid Inhibitors.
    Plyasova AA; Berrino E; Khan II; Veselovsky AV; Pokrovsky VS; Angeli A; Ferraroni M; Supuran CT; Pokrovskaya MV; Alexandrova SS; Gladilina YA; Sokolov NN; Hilal A; Carta F; Zhdanov DD
    J Med Chem; 2021 Aug; 64(15):11432-11444. PubMed ID: 34283610
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Berberine inhibits proliferation and induces G0/G1 phase arrest in colorectal cancer cells by downregulating IGF2BP3.
    Zhang Y; Liu X; Yu M; Xu M; Xiao Y; Ma W; Huang L; Li X; Ye X
    Life Sci; 2020 Nov; 260():118413. PubMed ID: 32926933
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Shikonin N-benzyl matrinic acid ester derivatives as novel telomerase inhibitors with potent activity against lung cancer cell lines.
    Han H; He C; Chen X; Luo Y; Yang M; Wen Z; Hu J; Lin F; Han M; Yin T; Yang R; Lin H; Qi J; Yang Y
    Bioorg Med Chem Lett; 2022 Feb; 57():128503. PubMed ID: 34922028
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Consequences of telomerase inhibition by BIBR1532 on proliferation and chemosensitivity of chondrosarcoma cell lines.
    Parsch D; Brassat U; Brümmendorf TH; Fellenberg J
    Cancer Invest; 2008 Jul; 26(6):590-6. PubMed ID: 18584350
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Telomerase inhibitor imetelstat has preclinical activity across the spectrum of non-small cell lung cancer oncogenotypes in a telomere length dependent manner.
    Frink RE; Peyton M; Schiller JH; Gazdar AF; Shay JW; Minna JD
    Oncotarget; 2016 May; 7(22):31639-51. PubMed ID: 27192120
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Telomerase inhibition, telomere attrition and proliferation arrest of cancer cells induced by phosphorothioate ASO-NLS conjugates targeting hTERC and siRNAs targeting hTERT.
    Diala I; Shiohama Y; Fujita T; Kotake Y; Demonacos C; Krstic-Demonacos M; Leva GD; Fujii M
    Nucleosides Nucleotides Nucleic Acids; 2020; 39(1-3):407-425. PubMed ID: 32310030
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Telomerase Inhibitors from Natural Products and Their Anticancer Potential.
    Ganesan K; Xu B
    Int J Mol Sci; 2017 Dec; 19(1):. PubMed ID: 29267203
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Downregulation of telomerase activity by diclofenac and curcumin is associated with cell cycle arrest and induction of apoptosis in colon cancer.
    Rana C; Piplani H; Vaish V; Nehru B; Sanyal SN
    Tumour Biol; 2015 Aug; 36(8):5999-6010. PubMed ID: 25744732
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A novel platinum compound inhibits telomerase activity in vitro and reduces telomere length in a human hepatoma cell line.
    Furuta M; Nozawa K; Takemura M; Izuta S; Murate T; Tsuchiya M; Yoshida K; Taka N; Nimura Y; Yoshida S
    Int J Cancer; 2003 May; 104(6):709-15. PubMed ID: 12640677
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Identification of human telomerase inhibitors having the core of N-acyl-4,5-dihydropyrazole with anticancer effects.
    Xiao X; Ni Y; Jia YM; Zheng M; Xu HF; Xu J; Liao C
    Bioorg Med Chem Lett; 2016 Mar; 26(6):1508-1511. PubMed ID: 26883149
    [TBL] [Abstract][Full Text] [Related]  

  • 16. How to inhibit telomerase activity for cancer therapy.
    Kyo S; Inoue M
    Curr Med Chem Anticancer Agents; 2002 Sep; 2(5):613-26. PubMed ID: 12678728
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Berberine inhibits cyclin D1 expression via suppressed binding of AP-1 transcription factors to CCND1 AP-1 motif.
    Luo Y; Hao Y; Shi TP; Deng WW; Li N
    Acta Pharmacol Sin; 2008 May; 29(5):628-33. PubMed ID: 18430372
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Ethanol extract of Antrodia camphorata inhibits proliferation of HCT-8 human colorectal cancer cells by arresting cell cycle progression and inducing apoptosis.
    Wang G; Wan Y; Zhao J; Hong Z
    Mol Med Rep; 2017 Oct; 16(4):4941-4947. PubMed ID: 28849005
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Berberine inhibits the proliferation of prostate cancer cells and induces G₀/G₁ or G₂/M phase arrest at different concentrations.
    Lu W; Du S; Wang J
    Mol Med Rep; 2015 May; 11(5):3920-4. PubMed ID: 25572870
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Facile construction of fused benzimidazole-isoquinolinones that induce cell-cycle arrest and apoptosis in colorectal cancer cells.
    He LJ; Yang DL; Li SQ; Zhang YJ; Tang Y; Lei J; Frett B; Lin HK; Li HY; Chen ZZ; Xu ZG
    Bioorg Med Chem; 2018 Aug; 26(14):3899-3908. PubMed ID: 29921474
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.