137 related articles for article (PubMed ID: 33461147)
1. Influence of FcRn binding properties on the gastrointestinal absorption and exposure profile of Fc molecules.
Lawrence SA; Blankenship R; Brown R; Estwick S; Ellis B; Thangaraju A; Datta-Mannan A
Bioorg Med Chem; 2021 Feb; 32():115942. PubMed ID: 33461147
[TBL] [Abstract][Full Text] [Related]
2. The neonatal Fc receptor (FcRn) binds independently to both sites of the IgG homodimer with identical affinity.
Abdiche YN; Yeung YA; Chaparro-Riggers J; Barman I; Strop P; Chin SM; Pham A; Bolton G; McDonough D; Lindquist K; Pons J; Rajpal A
MAbs; 2015; 7(2):331-43. PubMed ID: 25658443
[TBL] [Abstract][Full Text] [Related]
3. Global conformational changes in IgG-Fc upon mutation of the FcRn-binding site are not associated with altered antibody-dependent effector functions.
Burvenich IJG; Farrugia W; Liu Z; Makris D; King D; Gloria B; Perani A; Allan LC; Scott AM; Ramsland PA
Biochem J; 2018 Jul; 475(13):2179-2190. PubMed ID: 29794155
[TBL] [Abstract][Full Text] [Related]
4. Antibody Fc engineering for enhanced neonatal Fc receptor binding and prolonged circulation half-life.
Mackness BC; Jaworski JA; Boudanova E; Park A; Valente D; Mauriac C; Pasquier O; Schmidt T; Kabiri M; Kandira A; Radošević K; Qiu H
MAbs; 2019 Oct; 11(7):1276-1288. PubMed ID: 31216930
[TBL] [Abstract][Full Text] [Related]
5. Analytical FcRn affinity chromatography for functional characterization of monoclonal antibodies.
Schlothauer T; Rueger P; Stracke JO; Hertenberger H; Fingas F; Kling L; Emrich T; Drabner G; Seeber S; Auer J; Koch S; Papadimitriou A
MAbs; 2013; 5(4):576-86. PubMed ID: 23765230
[TBL] [Abstract][Full Text] [Related]
6. FcRn as a Transporter for Nasal Delivery of Biologics: A Systematic Review.
Fieux M; Le Quellec S; Bartier S; Coste A; Louis B; Giroudon C; Nourredine M; Bequignon E
Int J Mol Sci; 2021 Jun; 22(12):. PubMed ID: 34204226
[TBL] [Abstract][Full Text] [Related]
7. Charge-mediated influence of the antibody variable domain on FcRn-dependent pharmacokinetics.
Schoch A; Kettenberger H; Mundigl O; Winter G; Engert J; Heinrich J; Emrich T
Proc Natl Acad Sci U S A; 2015 May; 112(19):5997-6002. PubMed ID: 25918417
[TBL] [Abstract][Full Text] [Related]
8. Characterization of the 2:1 complex between the class I MHC-related Fc receptor and its Fc ligand in solution.
Martin WL; Bjorkman PJ
Biochemistry; 1999 Sep; 38(39):12639-47. PubMed ID: 10504233
[TBL] [Abstract][Full Text] [Related]
9. Crystal structure at 2.8 A of an FcRn/heterodimeric Fc complex: mechanism of pH-dependent binding.
Martin WL; West AP; Gan L; Bjorkman PJ
Mol Cell; 2001 Apr; 7(4):867-77. PubMed ID: 11336709
[TBL] [Abstract][Full Text] [Related]
10. Effect of individual Fc methionine oxidation on FcRn binding: Met252 oxidation impairs FcRn binding more profoundly than Met428 oxidation.
Gao X; Ji JA; Veeravalli K; Wang YJ; Zhang T; Mcgreevy W; Zheng K; Kelley RF; Laird MW; Liu J; Cromwell M
J Pharm Sci; 2015 Feb; 104(2):368-77. PubMed ID: 25175600
[TBL] [Abstract][Full Text] [Related]
11. Structural insights into neonatal Fc receptor-based recycling mechanisms.
Oganesyan V; Damschroder MM; Cook KE; Li Q; Gao C; Wu H; Dall'Acqua WF
J Biol Chem; 2014 Mar; 289(11):7812-24. PubMed ID: 24469444
[TBL] [Abstract][Full Text] [Related]
12. Development of a label-free FcRn-mediated transcytosis assay for in vitro characterization of FcRn interactions with therapeutic antibodies and Fc-fusion proteins.
Chung S; Lin YL; Nguyen V; Kamen L; Zheng K; Vora B; Song A
J Immunol Methods; 2018 Nov; 462():101-105. PubMed ID: 30030147
[TBL] [Abstract][Full Text] [Related]
13. Identification of human IgG1 variant with enhanced FcRn binding and without increased binding to rheumatoid factor autoantibody.
Maeda A; Iwayanagi Y; Haraya K; Tachibana T; Nakamura G; Nambu T; Esaki K; Hattori K; Igawa T
MAbs; 2017 Jul; 9(5):844-853. PubMed ID: 28387635
[TBL] [Abstract][Full Text] [Related]
14. Conformational Destabilization of Immunoglobulin G Increases the Low pH Binding Affinity with the Neonatal Fc Receptor.
Walters BT; Jensen PF; Larraillet V; Lin K; Patapoff T; Schlothauer T; Rand KD; Zhang J
J Biol Chem; 2016 Jan; 291(4):1817-1825. PubMed ID: 26627822
[TBL] [Abstract][Full Text] [Related]
15. Qualification of a homogeneous cell-based neonatal Fc receptor (FcRn) binding assay and its application to studies on Fc functionality of IgG-based therapeutics.
Mathur A; Arora T; Liu L; Crouse-Zeineddini J; Mukku V
J Immunol Methods; 2013 Apr; 390(1-2):81-91. PubMed ID: 23384837
[TBL] [Abstract][Full Text] [Related]
16. Antigen physiochemical properties allosterically effect the IgG Fc-region and Fc neonatal receptor affinity.
Sun Y; Estevez A; Schlothauer T; Wecksler AT
MAbs; 2020; 12(1):1802135. PubMed ID: 32795110
[TBL] [Abstract][Full Text] [Related]
17. Targeting the neonatal fc receptor for antigen delivery using engineered fc fragments.
Mi W; Wanjie S; Lo ST; Gan Z; Pickl-Herk B; Ober RJ; Ward ES
J Immunol; 2008 Dec; 181(11):7550-61. PubMed ID: 19017944
[TBL] [Abstract][Full Text] [Related]
18. Crystal structure at 2.2 A resolution of the MHC-related neonatal Fc receptor.
Burmeister WP; Gastinel LN; Simister NE; Blum ML; Bjorkman PJ
Nature; 1994 Nov; 372(6504):336-43. PubMed ID: 7969491
[TBL] [Abstract][Full Text] [Related]
19. Dissection of the neonatal Fc receptor (FcRn)-albumin interface using mutagenesis and anti-FcRn albumin-blocking antibodies.
Sand KM; Dalhus B; Christianson GJ; Bern M; Foss S; Cameron J; Sleep D; Bjørås M; Roopenian DC; Sandlie I; Andersen JT
J Biol Chem; 2014 Jun; 289(24):17228-39. PubMed ID: 24764301
[TBL] [Abstract][Full Text] [Related]
20. Crystal structure of an HSA/FcRn complex reveals recycling by competitive mimicry of HSA ligands at a pH-dependent hydrophobic interface.
Schmidt MM; Townson SA; Andreucci AJ; King BM; Schirmer EB; Murillo AJ; Dombrowski C; Tisdale AW; Lowden PA; Masci AL; Kovalchin JT; Erbe DV; Wittrup KD; Furfine ES; Barnes TM
Structure; 2013 Nov; 21(11):1966-78. PubMed ID: 24120761
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
