BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

395 related articles for article (PubMed ID: 33465425)

  • 1. Apoptotic activities of brusatol in human non-small cell lung cancer cells: Involvement of ROS-mediated mitochondrial-dependent pathway and inhibition of Nrf2-mediated antioxidant response.
    Xie J; Lai Z; Zheng X; Liao H; Xian Y; Li Q; Wu J; Ip S; Xie Y; Chen J; Su Z; Lin Z; Yang X
    Toxicology; 2021 Mar; 451():152680. PubMed ID: 33465425
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Apoptosis induced by bruceine D in human non‑small‑cell lung cancer cells involves mitochondrial ROS‑mediated death signaling.
    Xie JH; Lai ZQ; Zheng XH; Xian YF; Li Q; Ip SP; Xie YL; Chen JN; Su ZR; Lin ZX; Yang XB
    Int J Mol Med; 2019 Dec; 44(6):2015-2026. PubMed ID: 31638181
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The anti-hepatocellular carcinoma effect of Brucea javanica oil in ascitic tumor-bearing mice: The detection of brusatol and its role.
    Wang T; Dou Y; Lin G; Li Q; Nie J; Chen B; Xie J; Su Z; Zeng H; Chen J; Xie Y
    Biomed Pharmacother; 2021 Feb; 134():111122. PubMed ID: 33341052
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Apoptosis induced by the methanol extract of Salvia miltiorrhiza Bunge in non-small cell lung cancer through PTEN-mediated inhibition of PI3K/Akt pathway.
    Ye YT; Zhong W; Sun P; Wang D; Wang C; Hu LM; Qian JQ
    J Ethnopharmacol; 2017 Mar; 200():107-116. PubMed ID: 28088493
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Dehydrobruceine B enhances the cisplatin-induced cytotoxicity through regulation of the mitochondrial apoptotic pathway in lung cancer A549 cells.
    Huang Z; Yang G; Shen T; Wang X; Li H; Ren D
    Biomed Pharmacother; 2017 May; 89():623-631. PubMed ID: 28262615
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Brusatol enhances the efficacy of chemotherapy by inhibiting the Nrf2-mediated defense mechanism.
    Ren D; Villeneuve NF; Jiang T; Wu T; Lau A; Toppin HA; Zhang DD
    Proc Natl Acad Sci U S A; 2011 Jan; 108(4):1433-8. PubMed ID: 21205897
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Antioxidant tert-butylhydroquinone ameliorates arsenic-induced intracellular damages and apoptosis through induction of Nrf2-dependent antioxidant responses as well as stabilization of anti-apoptotic factor Bcl-2 in human keratinocytes.
    Duan X; Li J; Li W; Xing X; Zhang Y; Li W; Zhao L; Sun G; Gao XH; Li B
    Free Radic Biol Med; 2016 May; 94():74-87. PubMed ID: 26878773
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Brusatol isolated from Brucea javanica (L.) Merr. induces apoptotic death of insect cell lines.
    Zhang L; Feng X; Ma D; Yang J; Jiang H; Zhang Y; He W
    Pestic Biochem Physiol; 2013 Sep; 107(1):18-24. PubMed ID: 25149230
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Application of Mass Spectrometry Profiling to Establish Brusatol as an Inhibitor of Global Protein Synthesis.
    Vartanian S; Ma TP; Lee J; Haverty PM; Kirkpatrick DS; Yu K; Stokoe D
    Mol Cell Proteomics; 2016 Apr; 15(4):1220-31. PubMed ID: 26711467
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Inhibition of PDGFR by CP-673451 induces apoptosis and increases cisplatin cytotoxicity in NSCLC cells via inhibiting the Nrf2-mediated defense mechanism.
    Yang Y; Deng Y; Chen X; Zhang J; Chen Y; Li H; Wu Q; Yang Z; Zhang L; Liu B
    Toxicol Lett; 2018 Oct; 295():88-98. PubMed ID: 29857117
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Erlotinib induces the human non-small-cell lung cancer cells apoptosis via activating ROS-dependent JNK pathways.
    Shan F; Shao Z; Jiang S; Cheng Z
    Cancer Med; 2016 Nov; 5(11):3166-3175. PubMed ID: 27726288
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Brusatol Enhances the Radiosensitivity of A549 Cells by Promoting ROS Production and Enhancing DNA Damage.
    Sun X; Wang Q; Wang Y; Du L; Xu C; Liu Q
    Int J Mol Sci; 2016 Jun; 17(7):. PubMed ID: 27347930
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Brusatol provokes a rapid and transient inhibition of Nrf2 signaling and sensitizes mammalian cells to chemical toxicity-implications for therapeutic targeting of Nrf2.
    Olayanju A; Copple IM; Bryan HK; Edge GT; Sison RL; Wong MW; Lai ZQ; Lin ZX; Dunn K; Sanderson CM; Alghanem AF; Cross MJ; Ellis EC; Ingelman-Sundberg M; Malik HZ; Kitteringham NR; Goldring CE; Park BK
    Free Radic Biol Med; 2015 Jan; 78():202-12. PubMed ID: 25445704
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Apoptosis induction of dehydrobruceine B on two kinds of human lung cancer cell lines through mitochondrial-dependent pathway.
    Zhao L; Wen Q; Yang G; Huang Z; Shen T; Li H; Ren D
    Phytomedicine; 2016 Feb; 23(2):114-22. PubMed ID: 26926172
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Diosmetin induces apoptosis and enhances the chemotherapeutic efficacy of paclitaxel in non-small cell lung cancer cells via Nrf2 inhibition.
    Chen X; Wu Q; Chen Y; Zhang J; Li H; Yang Z; Yang Y; Deng Y; Zhang L; Liu B
    Br J Pharmacol; 2019 Jun; 176(12):2079-2094. PubMed ID: 30825187
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Seed Oil of Brucea javanicaInduces Cell Cycle Arrest and Apoptosis via Reactive Oxygen Species-Mediated Mitochondrial Dysfunction in Human Lung Cancer Cells.
    Wang D; Qu X; Zhuang X; Geng G; Hou J; Xu N; Li W; Hu T; Chen YS
    Nutr Cancer; 2016; 68(8):1394-1403. PubMed ID: 27635476
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Brusatol hinders the progression of bladder cancer by Chac1/Nrf2/SLC7A11 pathway.
    Yu X; He Z; Wang Z; Ke S; Wang H; Wang Q; Li S
    Exp Cell Res; 2024 May; 438(2):114053. PubMed ID: 38663476
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Plumbagin engenders apoptosis in lung cancer cells via caspase-9 activation and targeting mitochondrial-mediated ROS induction.
    Tripathi SK; Rengasamy KRR; Biswal BK
    Arch Pharm Res; 2020 Feb; 43(2):242-256. PubMed ID: 32034669
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Depletion of end-binding protein 1 (EB1) promotes apoptosis of human non-small-cell lung cancer cells via reactive oxygen species and Bax-mediated mitochondrial dysfunction.
    Kim MJ; Yun HS; Hong EH; Lee SJ; Baek JH; Lee CW; Yim JH; Kim JS; Park JK; Um HD; Hwang SG
    Cancer Lett; 2013 Oct; 339(1):15-24. PubMed ID: 23900080
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Nrf2 but not autophagy inhibition is associated with the survival of wild-type epidermal growth factor receptor non-small cell lung cancer cells.
    Zhou Y; Li Y; Ni HM; Ding WX; Zhong H
    Toxicol Appl Pharmacol; 2016 Nov; 310():140-149. PubMed ID: 27639429
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 20.