BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

255 related articles for article (PubMed ID: 33468657)

  • 1. PIAS1 modulates striatal transcription, DNA damage repair, and SUMOylation with relevance to Huntington's disease.
    Morozko EL; Smith-Geater C; Monteys AM; Pradhan S; Lim RG; Langfelder P; Kachemov M; Kulkarni JA; Zaifman J; Hill A; Stocksdale JT; Cullis PR; Wu J; Ochaba J; Miramontes R; Chakraborty A; Hazra TK; Lau A; St-Cyr S; Orellana I; Kopan L; Wang KQ; Yeung S; Leavitt BR; Reidling JC; Yang XW; Steffan JS; Davidson BL; Sarkar PS; Thompson LM
    Proc Natl Acad Sci U S A; 2021 Jan; 118(4):. PubMed ID: 33468657
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A PIAS1 Protective Variant S510G Delays polyQ Disease Onset by Modifying Protein Homeostasis.
    Lee YH; Tsai YS; Chang CC; Ho CC; Shih HM; Chen HM; Lai HL; Lee CW; Lee YC; Liao YC; Yang UC; Cheng TH; Chern Y; Soong BW
    Mov Disord; 2022 Apr; 37(4):767-777. PubMed ID: 34951052
    [TBL] [Abstract][Full Text] [Related]  

  • 3. PIAS1 Regulates Mutant Huntingtin Accumulation and Huntington's Disease-Associated Phenotypes In Vivo.
    Ochaba J; Monteys AM; O'Rourke JG; Reidling JC; Steffan JS; Davidson BL; Thompson LM
    Neuron; 2016 May; 90(3):507-20. PubMed ID: 27146268
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Mutant huntingtin impairs PNKP and ATXN3, disrupting DNA repair and transcription.
    Gao R; Chakraborty A; Geater C; Pradhan S; Gordon KL; Snowden J; Yuan S; Dickey AS; Choudhary S; Ashizawa T; Ellerby LM; La Spada AR; Thompson LM; Hazra TK; Sarkar PS
    Elife; 2019 Apr; 8():. PubMed ID: 30994454
    [TBL] [Abstract][Full Text] [Related]  

  • 5. SUMO-2 and PIAS1 modulate insoluble mutant huntingtin protein accumulation.
    O'Rourke JG; Gareau JR; Ochaba J; Song W; Raskó T; Reverter D; Lee J; Monteys AM; Pallos J; Mee L; Vashishtha M; Apostol BL; Nicholson TP; Illes K; Zhu YZ; Dasso M; Bates GP; Difiglia M; Davidson B; Wanker EE; Marsh JL; Lima CD; Steffan JS; Thompson LM
    Cell Rep; 2013 Jul; 4(2):362-75. PubMed ID: 23871671
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Phosphorylation of protein inhibitor of activated STAT1 (PIAS1) by MAPK-activated protein kinase-2 inhibits endothelial inflammation via increasing both PIAS1 transrepression and SUMO E3 ligase activity.
    Heo KS; Chang E; Takei Y; Le NT; Woo CH; Sullivan MA; Morrell C; Fujiwara K; Abe J
    Arterioscler Thromb Vasc Biol; 2013 Feb; 33(2):321-9. PubMed ID: 23202365
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Protein inhibitor of activated STAT 1 (PIAS1) is identified as the SUMO E3 ligase of CCAAT/enhancer-binding protein β (C/EBPβ) during adipogenesis.
    Liu Y; Zhang YD; Guo L; Huang HY; Zhu H; Huang JX; Liu Y; Zhou SR; Dang YJ; Li X; Tang QQ
    Mol Cell Biol; 2013 Nov; 33(22):4606-17. PubMed ID: 24061474
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The transcriptional activity of co-activator AIB1 is regulated by the SUMO E3 ligase PIAS1.
    Li S; Yang C; Hong Y; Bi H; Zhao F; Liu Y; Ao X; Pang P; Xing X; Chang AK; Xiao L; Zhang Y; Wu H
    Biol Cell; 2012 May; 104(5):287-96. PubMed ID: 22283414
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Linking nuclear matrix-localized PIAS1 to chromatin SUMOylation via direct binding of histones H3 and H2A.Z.
    Chen Z; Zhang Y; Guan Q; Zhang H; Luo J; Li J; Wei W; Xu X; Liao L; Wong J; Li J
    J Biol Chem; 2021 Oct; 297(4):101200. PubMed ID: 34537242
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Multisite SUMOylation restrains DNA polymerase η interactions with DNA damage sites.
    Guérillon C; Smedegaard S; Hendriks IA; Nielsen ML; Mailand N
    J Biol Chem; 2020 Jun; 295(25):8350-8362. PubMed ID: 32350109
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Identification of a non-covalent ternary complex formed by PIAS1, SUMO1, and UBC9 proteins involved in transcriptional regulation.
    Mascle XH; Lussier-Price M; Cappadocia L; Estephan P; Raiola L; Omichinski JG; Aubry M
    J Biol Chem; 2013 Dec; 288(51):36312-27. PubMed ID: 24174529
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The transcriptional repression activity of KyoT2 on the Notch/RBP-J pathway is regulated by PIAS1-catalyzed SUMOylation.
    Wang J; Qin H; Liang J; Zhu Y; Liang L; Zheng M; Han H
    J Mol Biol; 2007 Jun; 370(1):27-38. PubMed ID: 17509614
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The SUMO E3-ligase PIAS1 couples reactive oxygen species-dependent JNK activation to oxidative cell death.
    Leitao BB; Jones MC; Brosens JJ
    FASEB J; 2011 Oct; 25(10):3416-25. PubMed ID: 21676946
    [TBL] [Abstract][Full Text] [Related]  

  • 14. PIAS1 binds p300 and behaves as a coactivator or corepressor of the transcription factor c-Myb dependent on SUMO-status.
    Ledsaak M; Bengtsen M; Molværsmyr AK; Fuglerud BM; Matre V; Eskeland R; Gabrielsen OS
    Biochim Biophys Acta; 2016 May; 1859(5):705-18. PubMed ID: 27032383
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Mammalian SUMO E3-ligases PIAS1 and PIAS4 promote responses to DNA double-strand breaks.
    Galanty Y; Belotserkovskaya R; Coates J; Polo S; Miller KM; Jackson SP
    Nature; 2009 Dec; 462(7275):935-9. PubMed ID: 20016603
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Roles of the SUMO-related enzymes, PIAS1, PIAS4, and RNF4, in DNA double-strand break repair by homologous recombination.
    Han MM; Hirakawa M; Yamauchi M; Matsuda N
    Biochem Biophys Res Commun; 2022 Feb; 591():95-101. PubMed ID: 35007836
    [TBL] [Abstract][Full Text] [Related]  

  • 17. SUMO E3 ligase PIAS1 is a potential biomarker indicating stress susceptibility.
    Lin HY; Liu YS; Huang CY; Cathomas F; Liu K; Wang J; Cheng HT; Lai SW; Liu YC; Chen CJ; Lin C; Lu DY
    Psychoneuroendocrinology; 2020 Oct; 120():104800. PubMed ID: 32688147
    [TBL] [Abstract][Full Text] [Related]  

  • 18. PIAS1 negatively modulates virus triggered type I IFN signaling by blocking the DNA binding activity of IRF3.
    Li R; Pan Y; Shi DD; Zhang Y; Zhang J
    Antiviral Res; 2013 Nov; 100(2):546-54. PubMed ID: 24036127
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Downregulation of glial genes involved in synaptic function mitigates Huntington's disease pathogenesis.
    Onur TS; Laitman A; Zhao H; Keyho R; Kim H; Wang J; Mair M; Wang H; Li L; Perez A; de Haro M; Wan YW; Allen G; Lu B; Al-Ramahi I; Liu Z; Botas J
    Elife; 2021 Apr; 10():. PubMed ID: 33871358
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Progerin-Induced Transcriptional Changes in Huntington's Disease Human Pluripotent Stem Cell-Derived Neurons.
    Cohen-Carmon D; Sorek M; Lerner V; Divya MS; Nissim-Rafinia M; Yarom Y; Meshorer E
    Mol Neurobiol; 2020 Mar; 57(3):1768-1777. PubMed ID: 31834602
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.