BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

241 related articles for article (PubMed ID: 33471959)

  • 1. CRISPR/Cas9 screening identifies a kinetochore-microtubule dependent mechanism for Aurora-A inhibitor resistance in breast cancer.
    Chen A; Wen S; Liu F; Zhang Z; Liu M; Wu Y; He B; Yan M; Kang T; Lam EW; Wang Z; Liu Q
    Cancer Commun (Lond); 2021 Feb; 41(2):121-139. PubMed ID: 33471959
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Aurora B phosphorylates centromeric MCAK and regulates its localization and microtubule depolymerization activity.
    Lan W; Zhang X; Kline-Smith SL; Rosasco SE; Barrett-Wilt GA; Shabanowitz J; Hunt DF; Walczak CE; Stukenberg PT
    Curr Biol; 2004 Feb; 14(4):273-86. PubMed ID: 14972678
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Co-inhibition of Aurora A and Haspin kinases enhances survivin blockage and p53 induction for mitotic catastrophe and apoptosis in human colorectal cancer.
    Lin CI; Chen ZC; Chen CH; Chang YH; Lee TC; Tang TT; Yu TW; Yang CM; Tsai MC; Huang CC; Yang TW; Lin CC; Wang RH; Chiou GY; Jong YJ; Chao JI
    Biochem Pharmacol; 2022 Dec; 206():115289. PubMed ID: 36241092
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Genome-wide CRISPR screen uncovers a synergistic effect of combining Haspin and Aurora kinase B inhibition.
    Huang M; Feng X; Su D; Wang G; Wang C; Tang M; Paulucci-Holthauzen A; Hart T; Chen J
    Oncogene; 2020 May; 39(21):4312-4322. PubMed ID: 32300176
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Modulation of oxidative phosphorylation augments antineoplastic activity of mitotic aurora kinase inhibition.
    Zhang Z; Zeng D; Zhang W; Chen A; Lei J; Liu F; Deng B; Zhuo J; He B; Yan M; Lei X; Wang S; Lam EW; Liu Q; Wang Z
    Cell Death Dis; 2021 Sep; 12(10):893. PubMed ID: 34593753
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A perikinetochoric ring defined by MCAK and Aurora-B as a novel centromere domain.
    Parra MT; Gómez R; Viera A; Page J; Calvente A; Wordeman L; Rufas JS; Suja JA
    PLoS Genet; 2006 Jun; 2(6):e84. PubMed ID: 16741559
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Aurora B is enriched at merotelic attachment sites, where it regulates MCAK.
    Knowlton AL; Lan W; Stukenberg PT
    Curr Biol; 2006 Sep; 16(17):1705-10. PubMed ID: 16950107
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Spatiotemporal dynamics of Aurora B-PLK1-MCAK signaling axis orchestrates kinetochore bi-orientation and faithful chromosome segregation.
    Shao H; Huang Y; Zhang L; Yuan K; Chu Y; Dou Z; Jin C; Garcia-Barrio M; Liu X; Yao X
    Sci Rep; 2015 Jul; 5():12204. PubMed ID: 26206521
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Aurora B regulates MCAK at the mitotic centromere.
    Andrews PD; Ovechkina Y; Morrice N; Wagenbach M; Duncan K; Wordeman L; Swedlow JR
    Dev Cell; 2004 Feb; 6(2):253-68. PubMed ID: 14960279
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The investigational Aurora kinase A inhibitor MLN8237 induces defects in cell viability and cell-cycle progression in malignant bladder cancer cells in vitro and in vivo.
    Zhou N; Singh K; Mir MC; Parker Y; Lindner D; Dreicer R; Ecsedy JA; Zhang Z; Teh BT; Almasan A; Hansel DE
    Clin Cancer Res; 2013 Apr; 19(7):1717-28. PubMed ID: 23403633
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Inhibition of Aurora A enhances radiosensitivity in selected lung cancer cell lines.
    Liu N; Wang YA; Sun Y; Ecsedy J; Sun J; Li X; Wang P
    Respir Res; 2019 Oct; 20(1):230. PubMed ID: 31647033
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Polymer Nanovesicle-Mediated Delivery of MLN8237 Preferentially Inhibits Aurora Kinase A To Target RalA and Anchorage-Independent Growth in Breast Cancer Cells.
    Inchanalkar S; Deshpande NU; Kasherwal V; Jayakannan M; Balasubramanian N
    Mol Pharm; 2018 Aug; 15(8):3046-3059. PubMed ID: 29863884
    [TBL] [Abstract][Full Text] [Related]  

  • 13. NuSAP modulates the dynamics of kinetochore microtubules by attenuating MCAK depolymerisation activity.
    Li C; Zhang Y; Yang Q; Ye F; Sun SY; Chen ES; Liou YC
    Sci Rep; 2016 Jan; 6():18773. PubMed ID: 26733216
    [TBL] [Abstract][Full Text] [Related]  

  • 14. MCAK facilitates chromosome movement by promoting kinetochore microtubule turnover.
    Wordeman L; Wagenbach M; von Dassow G
    J Cell Biol; 2007 Dec; 179(5):869-79. PubMed ID: 18039936
    [TBL] [Abstract][Full Text] [Related]  

  • 15. An inner centromere protein that stimulates the microtubule depolymerizing activity of a KinI kinesin.
    Ohi R; Coughlin ML; Lane WS; Mitchison TJ
    Dev Cell; 2003 Aug; 5(2):309-21. PubMed ID: 12919681
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Combination of Eribulin and Aurora A Inhibitor MLN8237 Prevents Metastatic Colonization and Induces Cytotoxic Autophagy in Breast Cancer.
    Kozyreva VK; Kiseleva AA; Ice RJ; Jones BC; Loskutov YV; Matalkah F; Smolkin MB; Marinak K; Livengood RH; Salkeni MA; Wen S; Hazard HW; Layne GP; Walsh CM; Cantrell PS; Kilby GW; Mahavadi S; Shah N; Pugacheva EN
    Mol Cancer Ther; 2016 Aug; 15(8):1809-22. PubMed ID: 27235164
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Combined Aurora Kinase A and CHK1 Inhibition Enhances Radiosensitivity of Triple-Negative Breast Cancer Through Induction of Apoptosis and Mitotic Catastrophe Associated With Excessive DNA Damage.
    Li C; Liao J; Wang X; Chen FX; Guo X; Chen X
    Int J Radiat Oncol Biol Phys; 2023 Dec; 117(5):1241-1254. PubMed ID: 37393021
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Combined Aurora Kinase A (AURKA) and WEE1 Inhibition Demonstrates Synergistic Antitumor Effect in Squamous Cell Carcinoma of the Head and Neck.
    Lee JW; Parameswaran J; Sandoval-Schaefer T; Eoh KJ; Yang DH; Zhu F; Mehra R; Sharma R; Gaffney SG; Perry EB; Townsend JP; Serebriiskii IG; Golemis EA; Issaeva N; Yarbrough WG; Koo JS; Burtness B
    Clin Cancer Res; 2019 Jun; 25(11):3430-3442. PubMed ID: 30755439
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Aurora B phosphorylates multiple sites on mitotic centromere-associated kinesin to spatially and temporally regulate its function.
    Zhang X; Lan W; Ems-McClung SC; Stukenberg PT; Walczak CE
    Mol Biol Cell; 2007 Sep; 18(9):3264-76. PubMed ID: 17567953
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Aurora A inhibitor (MLN8237) plus vincristine plus rituximab is synthetic lethal and a potential curative therapy in aggressive B-cell non-Hodgkin lymphoma.
    Mahadevan D; Stejskal A; Cooke LS; Manziello A; Morales C; Persky DO; Fisher RI; Miller TP; Qi W
    Clin Cancer Res; 2012 Apr; 18(8):2210-9. PubMed ID: 22374334
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.