BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

395 related articles for article (PubMed ID: 33479166)

  • 1. Dynamic competition between SARS-CoV-2 NSP1 and mRNA on the human ribosome inhibits translation initiation.
    Lapointe CP; Grosely R; Johnson AG; Wang J; Fernández IS; Puglisi JD
    Proc Natl Acad Sci U S A; 2021 Feb; 118(6):. PubMed ID: 33479166
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Nonstructural Protein 1 of SARS-CoV-2 Is a Potent Pathogenicity Factor Redirecting Host Protein Synthesis Machinery toward Viral RNA.
    Yuan S; Peng L; Park JJ; Hu Y; Devarkar SC; Dong MB; Shen Q; Wu S; Chen S; Lomakin IB; Xiong Y
    Mol Cell; 2020 Dec; 80(6):1055-1066.e6. PubMed ID: 33188728
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Structural basis for translational shutdown and immune evasion by the Nsp1 protein of SARS-CoV-2.
    Thoms M; Buschauer R; Ameismeier M; Koepke L; Denk T; Hirschenberger M; Kratzat H; Hayn M; Mackens-Kiani T; Cheng J; Straub JH; Stürzel CM; Fröhlich T; Berninghausen O; Becker T; Kirchhoff F; Sparrer KMJ; Beckmann R
    Science; 2020 Sep; 369(6508):1249-1255. PubMed ID: 32680882
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The N-terminal domain of SARS-CoV-2 nsp1 plays key roles in suppression of cellular gene expression and preservation of viral gene expression.
    Mendez AS; Ly M; González-Sánchez AM; Hartenian E; Ingolia NT; Cate JH; Glaunsinger BA
    Cell Rep; 2021 Oct; 37(3):109841. PubMed ID: 34624207
    [TBL] [Abstract][Full Text] [Related]  

  • 5. SARS-CoV-2 Nsp1 binds the ribosomal mRNA channel to inhibit translation.
    Schubert K; Karousis ED; Jomaa A; Scaiola A; Echeverria B; Gurzeler LA; Leibundgut M; Thiel V; Mühlemann O; Ban N
    Nat Struct Mol Biol; 2020 Oct; 27(10):959-966. PubMed ID: 32908316
    [TBL] [Abstract][Full Text] [Related]  

  • 6. SARS-CoV-2 NSP1 induces mRNA cleavages on the ribosome.
    Tardivat Y; Sosnowski P; Tidu A; Westhof E; Eriani G; Martin F
    Nucleic Acids Res; 2023 Sep; 51(16):8677-8690. PubMed ID: 37503833
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Universal features of Nsp1-mediated translational shutdown by coronaviruses.
    Schubert K; Karousis ED; Ban I; Lapointe CP; Leibundgut M; Bäumlin E; Kummerant E; Scaiola A; Schönhut T; Ziegelmüller J; Puglisi JD; Mühlemann O; Ban N
    Mol Cell; 2023 Oct; 83(19):3546-3557.e8. PubMed ID: 37802027
    [TBL] [Abstract][Full Text] [Related]  

  • 8. SARS-CoV-2 Nsp1 mediated mRNA degradation requires mRNA interaction with the ribosome.
    Shehata SI; Parker R
    RNA Biol; 2023 Jan; 20(1):444-456. PubMed ID: 37415298
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Lysine 164 is critical for SARS-CoV-2 Nsp1 inhibition of host gene expression.
    Shen Z; Zhang G; Yang Y; Li M; Yang S; Peng G
    J Gen Virol; 2021 Jan; 102(1):. PubMed ID: 33151142
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Middle East Respiratory Syndrome Coronavirus nsp1 Inhibits Host Gene Expression by Selectively Targeting mRNAs Transcribed in the Nucleus while Sparing mRNAs of Cytoplasmic Origin.
    Lokugamage KG; Narayanan K; Nakagawa K; Terasaki K; Ramirez SI; Tseng CT; Makino S
    J Virol; 2015 Nov; 89(21):10970-81. PubMed ID: 26311885
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Clinically observed deletions in SARS-CoV-2 Nsp1 affect its stability and ability to inhibit translation.
    Kumar P; Schexnaydre E; Rafie K; Kurata T; Terenin I; Hauryliuk V; Carlson LA
    FEBS Lett; 2022 May; 596(9):1203-1213. PubMed ID: 35434785
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Nsp1 of SARS-CoV-2 stimulates host translation termination.
    Shuvalov A; Shuvalova E; Biziaev N; Sokolova E; Evmenov K; Pustogarov N; Arnautova A; Matrosova V; Egorova T; Alkalaeva E
    RNA Biol; 2021 Nov; 18(sup2):804-817. PubMed ID: 34793288
    [TBL] [Abstract][Full Text] [Related]  

  • 13. SARS-CoV-2 targets ribosomal RNA biogenesis.
    Yerlici VT; Astori A; Kejiou NS; Jordan CA; Khosraviani N; Chan JNY; Hakem R; Raught B; Palazzo AF; Mekhail K
    Cell Rep; 2024 Mar; 43(3):113891. PubMed ID: 38427561
    [TBL] [Abstract][Full Text] [Related]  

  • 14. An Evolutionarily Conserved Strategy for Ribosome Binding and Host Translation Inhibition by β-coronavirus Non-structural Protein 1.
    Maurina SF; O'Sullivan JP; Sharma G; Pineda Rodriguez DC; MacFadden A; Cendali F; Henen MA; Vögeli B; Kieft JS; Glasgow A; Steckelberg AL
    J Mol Biol; 2023 Oct; 435(20):168259. PubMed ID: 37660941
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Molecular Basis of SARS-CoV-2 Nsp1-Induced Immune Translational Shutdown as Revealed by All-Atom Simulations.
    Borišek J; Spinello A; Magistrato A
    J Phys Chem Lett; 2021 Dec; 12(48):11745-11750. PubMed ID: 34851631
    [TBL] [Abstract][Full Text] [Related]  

  • 16. In vitro reconstitution of SARS-CoV-2 Nsp1-induced mRNA cleavage reveals the key roles of the N-terminal domain of Nsp1 and the RRM domain of eIF3g.
    Abaeva IS; Arhab Y; Miścicka A; Hellen CUT; Pestova TV
    Genes Dev; 2023 Sep; 37(17-18):844-860. PubMed ID: 37821106
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The key features of SARS-CoV-2 leader and NSP1 required for viral escape of NSP1-mediated repression.
    Bujanic L; Shevchuk O; von Kügelgen N; Kalinina A; Ludwik K; Koppstein D; Zerna N; Sickmann A; Chekulaeva M
    RNA; 2022 May; 28(5):766-779. PubMed ID: 35232816
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Structural basis for translation inhibition by MERS-CoV Nsp1 reveals a conserved mechanism for betacoronaviruses.
    Devarkar SC; Vetick M; Balaji S; Lomakin IB; Yang L; Jin D; Gilbert WV; Chen S; Xiong Y
    Cell Rep; 2023 Oct; 42(10):113156. PubMed ID: 37733586
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Severe acute respiratory syndrome coronavirus protein nsp1 is a novel eukaryotic translation inhibitor that represses multiple steps of translation initiation.
    Lokugamage KG; Narayanan K; Huang C; Makino S
    J Virol; 2012 Dec; 86(24):13598-608. PubMed ID: 23035226
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Selective translational control of cellular and viral mRNAs by RPS3 mRNA binding.
    Havkin-Solomon T; Itzhaki E; Joffe N; Reuven N; Shaul Y; Dikstein R
    Nucleic Acids Res; 2023 May; 51(9):4208-4222. PubMed ID: 37070189
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 20.