BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

408 related articles for article (PubMed ID: 33485974)

  • 1. Exploration of components and mechanisms of Polygoni Multiflori Radix-induced hepatotoxicity using siRNA -mediated CYP3A4 or UGT1A1 knockdown liver cells.
    Hu YH; Li DK; Quan ZY; Wang CY; Zhou M; Sun ZX
    J Ethnopharmacol; 2021 Apr; 270():113845. PubMed ID: 33485974
    [TBL] [Abstract][Full Text] [Related]  

  • 2. [Comparative study on preparation of Polygoni Multiflori Radix based on hepatotoxic bioassay].
    Ma ZJ; Li XF; Lv Y; Jiang BQ; Zhao YL; Zhang YM; Zhao KJ; Wang JB; Xiao XH
    Zhongguo Zhong Yao Za Zhi; 2015 Jun; 40(12):2325-9. PubMed ID: 26591518
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Hepatoxicity of major constituents and extractions of Radix Polygoni Multiflori and Radix Polygoni Multiflori Praeparata.
    Yu J; Xie J; Mao XJ; Wang MJ; Li N; Wang J; Zhaori GT; Zhao RH
    J Ethnopharmacol; 2011 Oct; 137(3):1291-9. PubMed ID: 21840387
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Hepatotoxic assessment of Polygoni Multiflori Radix extract and toxicokinetic study of stilbene glucoside and anthraquinones in rats.
    Ma J; Zheng L; He YS; Li HJ
    J Ethnopharmacol; 2015 Mar; 162():61-8. PubMed ID: 25557036
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Study on the protection of water extracts of Polygoni Multiflori Radix and Polygoni Multiflori Radix Praeparata against NAFLD and its mechanism.
    Lin L; Hao Z; Zhang S; Shi L; Lu B; Xu H; Ji L
    J Ethnopharmacol; 2020 Apr; 252():112577. PubMed ID: 31953200
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Pharmacokinetic studies unveiled the drug-drug interaction between trans-2,3,5,4'-tetrahydroxystilbene-2-O-β-d-glucopyranoside and emodin that may contribute to the idiosyncratic hepatotoxicity of Polygoni Multiflori Radix.
    Xing Y; Wang L; Wang C; Zhang Y; Zhang Y; Hu L; Gao X; Han L; Yang W
    J Pharm Biomed Anal; 2019 Feb; 164():672-680. PubMed ID: 30472586
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Reduction of emodin-8-O-ß-D-glucoside content participates in processing-based detoxification of polygoni multiflori radix.
    Wang X; Zhao G; Ju C; Dong L; Liu Y; Ding Z; Li W; Peng Y; Zheng J
    Phytomedicine; 2023 Jun; 114():154750. PubMed ID: 36990007
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Enhanced absorption and inhibited metabolism of emodin by 2, 3, 5, 4'-tetrahydroxystilbene-2-O-β-D-glucopyranoside: Possible mechanisms for Polygoni Multiflori Radix-induced liver injury.
    Yu Q; Jiang LL; Luo N; Fan YX; Ma J; Li P; Li HJ
    Chin J Nat Med; 2017 Jun; 15(6):451-457. PubMed ID: 28629535
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The assessment of the chronic hepatotoxicity induced by Polygoni Multiflori Radix in rats: A pilot study by using untargeted metabolomics method.
    Xia XH; Yuan YY; Liu M
    J Ethnopharmacol; 2017 May; 203():182-190. PubMed ID: 28365236
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Lipid regulation effects of Polygoni Multiflori Radix, its processed products and its major substances on steatosis human liver cell line L02.
    Wang M; Zhao R; Wang W; Mao X; Yu J
    J Ethnopharmacol; 2012 Jan; 139(1):287-93. PubMed ID: 22120683
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Polygonum multiflorum Thunb. Induces hepatotoxicity in SD rats and hepatocyte spheroids by Disrupting the metabolism of bilirubin and bile acid.
    Wang Q; Wen H; Ma S; Zhang Y
    J Ethnopharmacol; 2022 Oct; 296():115461. PubMed ID: 35728710
    [TBL] [Abstract][Full Text] [Related]  

  • 12. In vitro effects of active components of Polygonum Multiflorum Radix on enzymes involved in the lipid metabolism.
    Wang W; He Y; Lin P; Li Y; Sun R; Gu W; Yu J; Zhao R
    J Ethnopharmacol; 2014 May; 153(3):763-70. PubMed ID: 24680992
    [TBL] [Abstract][Full Text] [Related]  

  • 13. [Comparison of processed and crude Polygoni Multiflori Radix induced rat liver injury and screening for sensitive indicators].
    Tu C; Jiang BQ; Zhao YL; Li CY; Li N; Li XF; Jia GL; Pang JY; Ma ZJ; Wang JB; Xiao XH
    Zhongguo Zhong Yao Za Zhi; 2015 Feb; 40(4):654-60. PubMed ID: 26137686
    [TBL] [Abstract][Full Text] [Related]  

  • 14. [Effect of six components in Polygoni Multiflori Radix on regulation of CYP3A4 mediated by human pregnane X receptor].
    Zhang ZY; Wang YG; Huang XY; Wang MX; Yang L; Ma ZC; Tang XL; Gao Y
    Zhongguo Zhong Yao Za Zhi; 2018 Oct; 43(20):4104-4110. PubMed ID: 30486538
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Identification of urine tauro-β-muricholic acid as a promising biomarker in Polygoni Multiflori Radix-induced hepatotoxicity by targeted metabolomics of bile acids.
    Zhao DS; Jiang LL; Fan YX; Dong LC; Ma J; Dong X; Xu XJ; Li P; Li HJ
    Food Chem Toxicol; 2017 Oct; 108(Pt B):532-542. PubMed ID: 28237774
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Stilbene glucoside inhibits the glucuronidation of emodin in rats through the down-regulation of UDP-glucuronosyltransferases 1A8: application to a drug-drug interaction study in Radix Polygoni Multiflori.
    Ma J; Zheng L; Deng T; Li CL; He YS; Li HJ; Li P
    J Ethnopharmacol; 2013 May; 147(2):335-40. PubMed ID: 23523942
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Hepatoprotection and hepatotoxicity of Heshouwu, a Chinese medicinal herb: Context of the paradoxical effect.
    Li H; Wang X; Liu Y; Pan D; Wang Y; Yang N; Xiang L; Cai X; Feng Y
    Food Chem Toxicol; 2017 Oct; 108(Pt B):407-418. PubMed ID: 27484243
    [TBL] [Abstract][Full Text] [Related]  

  • 18. [Guidelines for safe use of Polygoni Multiflori Radix].
    Zhongguo Zhong Yao Za Zhi; 2020 Mar; 45(5):961-966. PubMed ID: 32237468
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Inhibition of CYP3A4 enhances aloe-emodin induced hepatocyte injury.
    Hu YH; Quan ZY; Li DK; Wang CY; Sun ZX
    Toxicol In Vitro; 2022 Mar; 79():105276. PubMed ID: 34875353
    [TBL] [Abstract][Full Text] [Related]  

  • 20. 2,3,4',5-tetrahydroxystilbene-2-O-β-D-glucoside exacerbates acetaminophen-induced hepatotoxicity by inducing hepatic expression of CYP2E1, CYP3A4 and CYP1A2.
    Xu S; Liu J; Shi J; Wang Z; Ji L
    Sci Rep; 2017 Nov; 7(1):16511. PubMed ID: 29184146
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 21.