These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

224 related articles for article (PubMed ID: 33493514)

  • 1. G protein βγ translocation to the Golgi apparatus activates MAPK via p110γ-p101 heterodimers.
    Khater M; Wei Z; Xu X; Huang W; Lokeshwar BL; Lambert NA; Wu G
    J Biol Chem; 2021; 296():100325. PubMed ID: 33493514
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Gβγ translocation to the Golgi apparatus activates ARF1 to spatiotemporally regulate G protein-coupled receptor signaling to MAPK.
    Khater M; Bryant CN; Wu G
    J Biol Chem; 2021; 296():100805. PubMed ID: 34022220
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Different inhibition of Gβγ-stimulated class IB phosphoinositide 3-kinase (PI3K) variants by a monoclonal antibody. Specific function of p101 as a Gβγ-dependent regulator of PI3Kγ enzymatic activity.
    Shymanets A; Prajwal ; Vadas O; Czupalla C; LoPiccolo J; Brenowitz M; Ghigo A; Hirsch E; Krause E; Wetzker R; Williams RL; Harteneck C; Nürnberg B
    Biochem J; 2015 Jul; 469(1):59-69. PubMed ID: 26173259
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Gβγ is a direct regulator of endogenous p101/p110γ and p84/p110γ PI3Kγ complexes in mouse neutrophils.
    Rynkiewicz NK; Anderson KE; Suire S; Collins DM; Karanasios E; Vadas O; Williams R; Oxley D; Clark J; Stephens LR; Hawkins PT
    Sci Signal; 2020 Nov; 13(656):. PubMed ID: 33144519
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Molecular determinants of PI3Kγ-mediated activation downstream of G-protein-coupled receptors (GPCRs).
    Vadas O; Dbouk HA; Shymanets A; Perisic O; Burke JE; Abi Saab WF; Khalil BD; Harteneck C; Bresnick AR; Nürnberg B; Backer JM; Williams RL
    Proc Natl Acad Sci U S A; 2013 Nov; 110(47):18862-7. PubMed ID: 24190998
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The olfactory receptor OR51E2 activates ERK1/2 through the Golgi-localized Gβγ-PI3Kγ-ARF1 pathway in prostate cancer cells.
    Xu X; Khater M; Wu G
    Front Pharmacol; 2022; 13():1009380. PubMed ID: 36313302
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The p101 subunit of PI3Kγ restores activation by Gβ mutants deficient in stimulating p110γ.
    Shymanets A; Ahmadian MR; Kössmeier KT; Wetzker R; Harteneck C; Nürnberg B
    Biochem J; 2012 Feb; 441(3):851-8. PubMed ID: 22054284
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Ras is an indispensable coregulator of the class IB phosphoinositide 3-kinase p87/p110gamma.
    Kurig B; Shymanets A; Bohnacker T; Prajwal ; Brock C; Ahmadian MR; Schaefer M; Gohla A; Harteneck C; Wymann MP; Jeanclos E; Nürnberg B
    Proc Natl Acad Sci U S A; 2009 Dec; 106(48):20312-7. PubMed ID: 19906996
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Characterizing the interactions between the two subunits of the p101/p110gamma phosphoinositide 3-kinase and their role in the activation of this enzyme by G beta gamma subunits.
    Krugmann S; Hawkins PT; Pryer N; Braselmann S
    J Biol Chem; 1999 Jun; 274(24):17152-8. PubMed ID: 10358071
    [TBL] [Abstract][Full Text] [Related]  

  • 10. p87 and p101 subunits are distinct regulators determining class IB phosphoinositide 3-kinase (PI3K) specificity.
    Shymanets A; Prajwal ; Bucher K; Beer-Hammer S; Harteneck C; Nürnberg B
    J Biol Chem; 2013 Oct; 288(43):31059-68. PubMed ID: 24014027
    [TBL] [Abstract][Full Text] [Related]  

  • 11. G protein γ (Gγ) subtype dependent targeting of GRK2 to M3 receptor by Gβγ.
    Samaradivakara S; Kankanamge D; Senarath K; Ratnayake K; Karunarathne A
    Biochem Biophys Res Commun; 2018 Sep; 503(1):165-170. PubMed ID: 29864421
    [TBL] [Abstract][Full Text] [Related]  

  • 12. p84, a new Gbetagamma-activated regulatory subunit of the type IB phosphoinositide 3-kinase p110gamma.
    Suire S; Coadwell J; Ferguson GJ; Davidson K; Hawkins P; Stephens L
    Curr Biol; 2005 Mar; 15(6):566-70. PubMed ID: 15797027
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Assigning functional domains within the p101 regulatory subunit of phosphoinositide 3-kinase gamma.
    Voigt P; Brock C; Nürnberg B; Schaefer M
    J Biol Chem; 2005 Feb; 280(6):5121-7. PubMed ID: 15611065
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Molecular basis for differential activation of p101 and p84 complexes of PI3Kγ by Ras and GPCRs.
    Rathinaswamy MK; Jenkins ML; Duewell BR; Zhang X; Harris NJ; Evans JT; Stariha JTB; Dalwadi U; Fleming KD; Ranga-Prasad H; Yip CK; Williams RL; Hansen SD; Burke JE
    Cell Rep; 2023 Mar; 42(3):112172. PubMed ID: 36842083
    [TBL] [Abstract][Full Text] [Related]  

  • 15. PI3Kgamma adaptor subunits define coupling to degranulation and cell motility by distinct PtdIns(3,4,5)P3 pools in mast cells.
    Bohnacker T; Marone R; Collmann E; Calvez R; Hirsch E; Wymann MP
    Sci Signal; 2009 Jun; 2(74):ra27. PubMed ID: 19509406
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The Human Cytomegalovirus US27 Gene Product Constitutively Activates Antioxidant Response Element-Mediated Transcription through G
    Boeck JM; Stowell GA; O'Connor CM; Spencer JV
    J Virol; 2018 Dec; 92(23):. PubMed ID: 30209167
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Inducible Inhibition of Gβγ Reveals Localization-dependent Functions at the Plasma Membrane and Golgi.
    Klayman LM; Wedegaertner PB
    J Biol Chem; 2017 Feb; 292(5):1773-1784. PubMed ID: 27994056
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Molecular basis for Gβγ-mediated activation of phosphoinositide 3-kinase γ.
    Chen CL; Syahirah R; Ravala SK; Yen YC; Klose T; Deng Q; Tesmer JJG
    Nat Struct Mol Biol; 2024 Aug; 31(8):1198-1207. PubMed ID: 38565696
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Protein Kinase D and Gβγ Subunits Mediate Agonist-evoked Translocation of Protease-activated Receptor-2 from the Golgi Apparatus to the Plasma Membrane.
    Jensen DD; Zhao P; Jimenez-Vargas NN; Lieu T; Gerges M; Yeatman HR; Canals M; Vanner SJ; Poole DP; Bunnett NW
    J Biol Chem; 2016 May; 291(21):11285-99. PubMed ID: 27030010
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Roles of non-catalytic subunits in gbetagamma-induced activation of class I phosphoinositide 3-kinase isoforms beta and gamma.
    Maier U; Babich A; Nürnberg B
    J Biol Chem; 1999 Oct; 274(41):29311-7. PubMed ID: 10506190
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.