BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

143 related articles for article (PubMed ID: 33495803)

  • 1. Discovery of natural adenosine monophosphate‑activated protein kinase activators through virtual screening and activity verification studies.
    Hao J; Yang Z; Li J; Han L; Zhang Y; Wang T
    Mol Med Rep; 2021 Mar; 23(3):. PubMed ID: 33495803
    [TBL] [Abstract][Full Text] [Related]  

  • 2. In silico Analysis of AMP-activated Protein Kinase and Ligand-based Virtual Screening for Identification of Novel AMPK Activators.
    Ghaffar A; Batool S; Mushtaq G; Kamal MA
    Curr Comput Aided Drug Des; 2017; 13(3):222-233. PubMed ID: 28294049
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Identification of Direct Activator of Adenosine Monophosphate-Activated Protein Kinase (AMPK) by Structure-Based Virtual Screening and Molecular Docking Approach.
    Huang T; Sun J; Zhou S; Gao J; Liu Y
    Int J Mol Sci; 2017 Jun; 18(7):. PubMed ID: 28665353
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Identification of potential AMPK activator by pharmacophore modeling, molecular docking and QSAR study.
    Li Y; Peng J; Li P; Du H; Li Y; Liu X; Zhang L; Wang LL; Zuo Z
    Comput Biol Chem; 2019 Apr; 79():165-176. PubMed ID: 30836318
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Biophysical Interactions of Direct AMPK Activators.
    Kurumbail RG; West GM; Dharmarajan V; Borzilleri KA; Withka JM; Ward J; Reyes AR; Rajamohan F; Griffin PR; Calabrese MF
    Methods Mol Biol; 2018; 1732():29-55. PubMed ID: 29480467
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Probing the enzyme kinetics, allosteric modulation and activation of α1- and α2-subunit-containing AMP-activated protein kinase (AMPK) heterotrimeric complexes by pharmacological and physiological activators.
    Rajamohan F; Reyes AR; Frisbie RK; Hoth LR; Sahasrabudhe P; Magyar R; Landro JA; Withka JM; Caspers NL; Calabrese MF; Ward J; Kurumbail RG
    Biochem J; 2016 Mar; 473(5):581-92. PubMed ID: 26635351
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Ligand-based modeling followed by in vitro bioassay yielded new potent glucokinase activators.
    Taha MO; Habash M; Hatmal MM; Abdelazeem AH; Qandil A
    J Mol Graph Model; 2015 Mar; 56():91-102. PubMed ID: 25574766
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Pharmacophore-based virtual screening approach for identification of potent natural modulatory compounds of human Toll-like receptor 7.
    Gupta CL; Babu Khan M; Ampasala DR; Akhtar S; Dwivedi UN; Bajpai P
    J Biomol Struct Dyn; 2019 Nov; 37(18):4721-4736. PubMed ID: 30661449
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Design, synthesis and biological evaluation of mogrol derivatives as a novel class of AMPKα2β1γ1 activators.
    Wang J; Liu J; Xie Z; Li J; Li J; Hu L
    Bioorg Med Chem Lett; 2020 Jan; 30(2):126790. PubMed ID: 31744674
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Pharmacophore modeling and virtual screening in search of novel Bruton's tyrosine kinase inhibitors.
    Sharma A; Thelma BK
    J Mol Model; 2019 Jun; 25(7):179. PubMed ID: 31172362
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Ligand-based and e-pharmacophore modeling, 3D-QSAR and hierarchical virtual screening to identify dual inhibitors of spleen tyrosine kinase (Syk) and janus kinase 3 (JAK3).
    Kaur M; Silakari O
    J Biomol Struct Dyn; 2017 Nov; 35(14):3043-3060. PubMed ID: 27678281
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Repurposing existing drugs for new AMPK activators as a strategy to extend lifespan: a computer-aided drug discovery study.
    Mofidifar S; Sohraby F; Bagheri M; Aryapour H
    Biogerontology; 2018 Apr; 19(2):133-143. PubMed ID: 29335817
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Development of Potent Adenosine Monophosphate Activated Protein Kinase (AMPK) Activators.
    Dokla EM; Fang CS; Lai PT; Kulp SK; Serya RA; Ismail NS; Abouzid KA; Chen CS
    ChemMedChem; 2015 Nov; 10(11):1915-23. PubMed ID: 26350292
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Structures of AMP-activated protein kinase bound to novel pharmacological activators in phosphorylated, non-phosphorylated, and nucleotide-free states.
    Yan Y; Zhou XE; Novick SJ; Shaw SJ; Li Y; Brunzelle JS; Hitoshi Y; Griffin PR; Xu HE; Melcher K
    J Biol Chem; 2019 Jan; 294(3):953-967. PubMed ID: 30478170
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Recent progress in the identification of adenosine monophosphate-activated protein kinase (AMPK) activators.
    Cameron KO; Kurumbail RG
    Bioorg Med Chem Lett; 2016 Nov; 26(21):5139-5148. PubMed ID: 27727125
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Discovery, synthesis, and structure-activity relationships of 20(S)-protopanaxadiol (PPD) derivatives as a novel class of AMPKα2β1γ1 activators.
    Liu J; Chen D; Liu P; He M; Li J; Li J; Hu L
    Eur J Med Chem; 2014 May; 79():340-9. PubMed ID: 24747289
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Natural activators of adenosine 5'-monophosphate (AMP)-activated protein kinase (AMPK) and their pharmacological activities.
    Vazirian M; Nabavi SM; Jafari S; Manayi A
    Food Chem Toxicol; 2018 Dec; 122():69-79. PubMed ID: 30290216
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Towards multi-target antidiabetic agents: Discovery of biphenyl-benzimidazole conjugates as AMPK activators.
    Babkov DA; Zhukowskaya ON; Borisov AV; Babkova VA; Sokolova EV; Brigadirova AA; Litvinov RA; Kolodina AA; Morkovnik AS; Sochnev VS; Borodkin GS; Spasov AA
    Bioorg Med Chem Lett; 2019 Sep; 29(17):2443-2447. PubMed ID: 31358465
    [TBL] [Abstract][Full Text] [Related]  

  • 19. In Silico Design of Novel Sirtuin 1 Enzyme Activators for the Treatment of Age-related Diseases and Life Span.
    Ertan-Bolelli T; Bolelli K
    Curr Comput Aided Drug Des; 2021; 17(3):412-420. PubMed ID: 32321406
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Design, synthesis, and biological evaluation of 1,2,4-oxadiazole-containing pyrazolo[3,4-b]pyridinones as a new series of AMPKɑ1β1γ1 activators.
    Xiao Z; Peng Y; Zheng B; Chang Q; Guo Y; Chen Z; Li Q; Hu G
    Arch Pharm (Weinheim); 2021 Jul; 354(7):e2000458. PubMed ID: 33683726
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.