BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

183 related articles for article (PubMed ID: 33499723)

  • 1. Brain pharmacokinetics of anti-transferrin receptor antibody affinity variants in rats determined using microdialysis.
    Chang HY; Wu S; Li Y; Zhang W; Burrell M; Webster CI; Shah DK
    MAbs; 2021; 13(1):1874121. PubMed ID: 33499723
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Towards a translational physiologically-based pharmacokinetic (PBPK) model for receptor-mediated transcytosis of anti-transferrin receptor monoclonal antibodies in the central nervous system.
    Chang HY; Wu S; Chowdhury EA; Shah DK
    J Pharmacokinet Pharmacodyn; 2022 Jun; 49(3):337-362. PubMed ID: 35092540
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Intracellular sorting and transcytosis of the rat transferrin receptor antibody OX26 across the blood-brain barrier in vitro is dependent on its binding affinity.
    Haqqani AS; Thom G; Burrell M; Delaney CE; Brunette E; Baumann E; Sodja C; Jezierski A; Webster C; Stanimirovic DB
    J Neurochem; 2018 Sep; 146(6):735-752. PubMed ID: 29877588
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Enhanced Delivery of Galanin Conjugates to the Brain through Bioengineering of the Anti-Transferrin Receptor Antibody OX26.
    Thom G; Burrell M; Haqqani AS; Yogi A; Lessard E; Brunette E; Delaney C; Baumann E; Callaghan D; Rodrigo N; Webster CI; Stanimirovic DB
    Mol Pharm; 2018 Apr; 15(4):1420-1431. PubMed ID: 29485883
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Advanced translational PBPK model for transferrin receptor-mediated drug delivery to the brain.
    Sato S; Liu S; Goto A; Yoneyama T; Okita K; Yamamoto S; Hirabayashi H; Iwasaki S; Kusuhara H
    J Control Release; 2023 May; 357():379-393. PubMed ID: 37031741
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Boosting brain uptake of a therapeutic antibody by reducing its affinity for a transcytosis target.
    Yu YJ; Zhang Y; Kenrick M; Hoyte K; Luk W; Lu Y; Atwal J; Elliott JM; Prabhu S; Watts RJ; Dennis MS
    Sci Transl Med; 2011 May; 3(84):84ra44. PubMed ID: 21613623
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Antibody pharmacokinetics in rat brain determined using microdialysis.
    Chang HY; Morrow K; Bonacquisti E; Zhang W; Shah DK
    MAbs; 2018; 10(6):843-853. PubMed ID: 29944439
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Characterization of basigin monoclonal antibodies for receptor-mediated drug delivery to the brain.
    Christensen SC; Krogh BO; Jensen A; Andersen CBF; Christensen S; Nielsen MS
    Sci Rep; 2020 Sep; 10(1):14582. PubMed ID: 32884039
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Pharmacokinetics and brain uptake of a genetically engineered bifunctional fusion antibody targeting the mouse transferrin receptor.
    Boado RJ; Zhou QH; Lu JZ; Hui EK; Pardridge WM
    Mol Pharm; 2010 Feb; 7(1):237-44. PubMed ID: 19921848
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Increased brain uptake of targeted nanoparticles by adding an acid-cleavable linkage between transferrin and the nanoparticle core.
    Clark AJ; Davis ME
    Proc Natl Acad Sci U S A; 2015 Oct; 112(40):12486-91. PubMed ID: 26392563
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Pharmacokinetics and blood-brain barrier transport of an anti-transferrin receptor monoclonal antibody (OX26) in rats after chronic treatment with the antibody.
    Wu D; Pardridge WM
    Drug Metab Dispos; 1998 Sep; 26(9):937-9. PubMed ID: 9733674
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Restricted transport of anti-transferrin receptor antibody (OX26) through the blood-brain barrier in the rat.
    Moos T; Morgan EH
    J Neurochem; 2001 Oct; 79(1):119-29. PubMed ID: 11595764
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Study of the transcytosis of an anti-transferrin receptor antibody with a Fab' cargo across the blood-brain barrier in mice.
    Manich G; Cabezón I; del Valle J; Duran-Vilaregut J; Camins A; Pallàs M; Pelegrí C; Vilaplana J
    Eur J Pharm Sci; 2013 Jul; 49(4):556-64. PubMed ID: 23748097
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Brain uptake of multivalent and multi-specific DVD-Ig proteins after systemic administration.
    Karaoglu Hanzatian D; Schwartz A; Gizatullin F; Erickson J; Deng K; Villanueva R; Stedman C; Harris C; Ghayur T; Goodearl A
    MAbs; 2018 Jul; 10(5):765-777. PubMed ID: 29771629
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Transcytosis of protein through the mammalian cerebral epithelium and endothelium. III. Receptor-mediated transcytosis through the blood-brain barrier of blood-borne transferrin and antibody against the transferrin receptor.
    Broadwell RD; Baker-Cairns BJ; Friden PM; Oliver C; Villegas JC
    Exp Neurol; 1996 Nov; 142(1):47-65. PubMed ID: 8912898
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Targeting rat anti-mouse transferrin receptor monoclonal antibodies through blood-brain barrier in mouse.
    Lee HJ; Engelhardt B; Lesley J; Bickel U; Pardridge WM
    J Pharmacol Exp Ther; 2000 Mar; 292(3):1048-52. PubMed ID: 10688622
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Pharmacokinetics and brain uptake of lactoferrin in rats.
    Ji B; Maeda J; Higuchi M; Inoue K; Akita H; Harashima H; Suhara T
    Life Sci; 2006 Jan; 78(8):851-5. PubMed ID: 16165165
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A human blood-brain barrier transcytosis assay reveals antibody transcytosis influenced by pH-dependent receptor binding.
    Sade H; Baumgartner C; Hugenmatter A; Moessner E; Freskgård PO; Niewoehner J
    PLoS One; 2014; 9(4):e96340. PubMed ID: 24788759
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A Perfused In Vitro Human iPSC-Derived Blood-Brain Barrier Faithfully Mimics Transferrin Receptor-Mediated Transcytosis of Therapeutic Antibodies.
    Burgio F; Gaiser C; Brady K; Gatta V; Class R; Schrage R; Suter-Dick L
    Cell Mol Neurobiol; 2023 Nov; 43(8):4173-4187. PubMed ID: 37698826
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mathematical PKPD and safety model of bispecific TfR/BACE1 antibodies for the optimization of antibody uptake in brain.
    Gadkar K; Yadav DB; Zuchero JY; Couch JA; Kanodia J; Kenrick MK; Atwal JK; Dennis MS; Prabhu S; Watts RJ; Joseph SB; Ramanujan S
    Eur J Pharm Biopharm; 2016 Apr; 101():53-61. PubMed ID: 26820920
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.