273 related articles for article (PubMed ID: 33500247)
1. Serine Biosynthesis Is a Metabolic Vulnerability in IDH2-Driven Breast Cancer Progression.
Barnabas GD; Lee JS; Shami T; Harel M; Beck L; Selitrennik M; Jerby-Arnon L; Erez N; Ruppin E; Geiger T
Cancer Res; 2021 Mar; 81(6):1443-1456. PubMed ID: 33500247
[TBL] [Abstract][Full Text] [Related]
2. Selective loss of phosphoserine aminotransferase 1 (PSAT1) suppresses migration, invasion, and experimental metastasis in triple negative breast cancer.
Metcalf S; Dougherty S; Kruer T; Hasan N; Biyik-Sit R; Reynolds L; Clem BF
Clin Exp Metastasis; 2020 Feb; 37(1):187-197. PubMed ID: 31630284
[TBL] [Abstract][Full Text] [Related]
3. Functional genomics reveal that the serine synthesis pathway is essential in breast cancer.
Possemato R; Marks KM; Shaul YD; Pacold ME; Kim D; Birsoy K; Sethumadhavan S; Woo HK; Jang HG; Jha AK; Chen WW; Barrett FG; Stransky N; Tsun ZY; Cowley GS; Barretina J; Kalaany NY; Hsu PP; Ottina K; Chan AM; Yuan B; Garraway LA; Root DE; Mino-Kenudson M; Brachtel EF; Driggers EM; Sabatini DM
Nature; 2011 Aug; 476(7360):346-50. PubMed ID: 21760589
[TBL] [Abstract][Full Text] [Related]
4. Enhanced serine production by bone metastatic breast cancer cells stimulates osteoclastogenesis.
Pollari S; Käkönen SM; Edgren H; Wolf M; Kohonen P; Sara H; Guise T; Nees M; Kallioniemi O
Breast Cancer Res Treat; 2011 Jan; 125(2):421-30. PubMed ID: 20352489
[TBL] [Abstract][Full Text] [Related]
5. Repression of phosphoglycerate dehydrogenase sensitizes triple-negative breast cancer to doxorubicin.
Zhang X; Bai W
Cancer Chemother Pharmacol; 2016 Sep; 78(3):655-9. PubMed ID: 27473325
[TBL] [Abstract][Full Text] [Related]
6. ASS1 inhibits triple-negative breast cancer by regulating PHGDH stability and de novo serine synthesis.
Luo W; Zou Z; Nie Y; Luo J; Ming Z; Hu X; Luo T; Ouyang M; Liu M; Tang H; Xie Y; Peng K; Chen L; Zhou J; Luo Z
Cell Death Dis; 2024 May; 15(5):319. PubMed ID: 38710705
[TBL] [Abstract][Full Text] [Related]
7. Menin regulates the serine biosynthetic pathway in Ewing sarcoma.
Svoboda LK; Teh SSK; Sud S; Kerk S; Zebolsky A; Treichel S; Thomas D; Halbrook CJ; Lee HJ; Kremer D; Zhang L; Klossowski S; Bankhead AR; Magnuson B; Ljungman M; Cierpicki T; Grembecka J; Lyssiotis CA; Lawlor ER
J Pathol; 2018 Jul; 245(3):324-336. PubMed ID: 29672864
[TBL] [Abstract][Full Text] [Related]
8. PHGDH as a Key Enzyme for Serine Biosynthesis in HIF2α-Targeting Therapy for Renal Cell Carcinoma.
Yoshino H; Nohata N; Miyamoto K; Yonemori M; Sakaguchi T; Sugita S; Itesako T; Kofuji S; Nakagawa M; Dahiya R; Enokida H
Cancer Res; 2017 Nov; 77(22):6321-6329. PubMed ID: 28951458
[TBL] [Abstract][Full Text] [Related]
9. ATF3 promotes the serine synthesis pathway and tumor growth under dietary serine restriction.
Li X; Gracilla D; Cai L; Zhang M; Yu X; Chen X; Zhang J; Long X; Ding HF; Yan C
Cell Rep; 2021 Sep; 36(12):109706. PubMed ID: 34551291
[TBL] [Abstract][Full Text] [Related]
10. The NAD
Murphy JP; Giacomantonio MA; Paulo JA; Everley RA; Kennedy BE; Pathak GP; Clements DR; Kim Y; Dai C; Sharif T; Gygi SP; Gujar S
Cell Rep; 2018 Aug; 24(9):2381-2391.e5. PubMed ID: 30157431
[TBL] [Abstract][Full Text] [Related]
11. Limited Environmental Serine and Glycine Confer Brain Metastasis Sensitivity to PHGDH Inhibition.
Ngo B; Kim E; Osorio-Vasquez V; Doll S; Bustraan S; Liang RJ; Luengo A; Davidson SM; Ali A; Ferraro GB; Fischer GM; Eskandari R; Kang DS; Ni J; Plasger A; Rajasekhar VK; Kastenhuber ER; Bacha S; Sriram RK; Stein BD; Bakhoum SF; Snuderl M; Cotzia P; Healey JH; Mainolfi N; Suri V; Friedman A; Manfredi M; Sabatini DM; Jones DR; Yu M; Zhao JJ; Jain RK; Keshari KR; Davies MA; Vander Heiden MG; Hernando E; Mann M; Cantley LC; Pacold ME
Cancer Discov; 2020 Sep; 10(9):1352-1373. PubMed ID: 32571778
[TBL] [Abstract][Full Text] [Related]
12. High level PHGDH expression in breast is predominantly associated with keratin 5-positive cell lineage independently of malignancy.
Gromova I; Gromov P; Honma N; Kumar S; Rimm D; Talman ML; Wielenga VT; Moreira JM
Mol Oncol; 2015 Oct; 9(8):1636-54. PubMed ID: 26026368
[TBL] [Abstract][Full Text] [Related]
13. In Vivo Evidence for Serine Biosynthesis-Defined Sensitivity of Lung Metastasis, but Not of Primary Breast Tumors, to mTORC1 Inhibition.
Rinaldi G; Pranzini E; Van Elsen J; Broekaert D; Funk CM; Planque M; Doglioni G; Altea-Manzano P; Rossi M; Geldhof V; Teoh ST; Ross C; Hunter KW; Lunt SY; Grünewald TGP; Fendt SM
Mol Cell; 2021 Jan; 81(2):386-397.e7. PubMed ID: 33340488
[TBL] [Abstract][Full Text] [Related]
14. Wild-type IDH2 is a therapeutic target for triple-negative breast cancer.
Li JJ; Yu T; Zeng P; Tian J; Liu P; Qiao S; Wen S; Hu Y; Liu Q; Lu W; Zhang H; Huang P
Nat Commun; 2024 Apr; 15(1):3445. PubMed ID: 38658533
[TBL] [Abstract][Full Text] [Related]
15. Phosphoglycerate dehydrogenase is dispensable for breast tumor maintenance and growth.
Chen J; Chung F; Yang G; Pu M; Gao H; Jiang W; Yin H; Capka V; Kasibhatla S; Laffitte B; Jaeger S; Pagliarini R; Chen Y; Zhou W
Oncotarget; 2013 Dec; 4(12):2502-11. PubMed ID: 24318446
[TBL] [Abstract][Full Text] [Related]
16. Reducing the serine availability complements the inhibition of the glutamine metabolism to block leukemia cell growth.
Polet F; Corbet C; Pinto A; Rubio LI; Martherus R; Bol V; Drozak X; Grégoire V; Riant O; Feron O
Oncotarget; 2016 Jan; 7(2):1765-76. PubMed ID: 26625201
[TBL] [Abstract][Full Text] [Related]
17. Metabolic shift to serine biosynthesis through 3-PG accumulation and PHGDH induction promotes tumor growth in pancreatic cancer.
Itoyama R; Yasuda-Yoshihara N; Kitamura F; Yasuda T; Bu L; Yonemura A; Uchihara T; Arima K; Hu X; Jun Z; Okamoto Y; Akiyama T; Yamashita K; Nakao Y; Yusa T; Kitano Y; Higashi T; Miyata T; Imai K; Hayashi H; Yamashita YI; Mikawa T; Kondoh H; Baba H; Ishimoto T
Cancer Lett; 2021 Dec; 523():29-42. PubMed ID: 34508795
[TBL] [Abstract][Full Text] [Related]
18. p73 regulates serine biosynthesis in cancer.
Amelio I; Markert EK; Rufini A; Antonov AV; Sayan BS; Tucci P; Agostini M; Mineo TC; Levine AJ; Melino G
Oncogene; 2014 Oct; 33(42):5039-46. PubMed ID: 24186203
[TBL] [Abstract][Full Text] [Related]
19. The Role of D-3-Phosphoglycerate Dehydrogenase in Cancer.
Zhao X; Fu J; Du J; Xu W
Int J Biol Sci; 2020; 16(9):1495-1506. PubMed ID: 32226297
[TBL] [Abstract][Full Text] [Related]
20. Inhibiting phosphoglycerate dehydrogenase counteracts chemotherapeutic efficacy against MYCN-amplified neuroblastoma.
Arlt B; Zasada C; Baum K; Wuenschel J; Mastrobuoni G; Lodrini M; Astrahantseff K; Winkler A; Schulte JH; Finkler S; Forbes M; Hundsdoerfer P; Guergen D; Hoffmann J; Wolf J; Eggert A; Kempa S; Deubzer HE
Int J Cancer; 2021 Mar; 148(5):1219-1232. PubMed ID: 33284994
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]