These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

138 related articles for article (PubMed ID: 33502191)

  • 1. Machine Learning Models to Predict Inhibition of the Bile Salt Export Pump.
    McLoughlin KS; Jeong CG; Sweitzer TD; Minnich AJ; Tse MJ; Bennion BJ; Allen JE; Calad-Thomson S; Rush TS; Brase JM
    J Chem Inf Model; 2021 Feb; 61(2):587-602. PubMed ID: 33502191
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Risk factors for development of cholestatic drug-induced liver injury: inhibition of hepatic basolateral bile acid transporters multidrug resistance-associated proteins 3 and 4.
    Köck K; Ferslew BC; Netterberg I; Yang K; Urban TJ; Swaan PW; Stewart PW; Brouwer KL
    Drug Metab Dispos; 2014 Apr; 42(4):665-74. PubMed ID: 24154606
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Structure based classification for bile salt export pump (BSEP) inhibitors using comparative structural modeling of human BSEP.
    Jain S; Grandits M; Richter L; Ecker GF
    J Comput Aided Mol Des; 2017 Jun; 31(6):507-521. PubMed ID: 28527154
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The role of bile salt export pump gene repression in drug-induced cholestatic liver toxicity.
    Garzel B; Yang H; Zhang L; Huang SM; Polli JE; Wang H
    Drug Metab Dispos; 2014 Mar; 42(3):318-22. PubMed ID: 24335466
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Effect of a Common Genetic Variant (p.V444A) in the Bile Salt Export Pump on the Inhibition of Bile Acid Transport by Cholestatic Medications.
    Ali I; Khalid S; Stieger B; Brouwer KLR
    Mol Pharm; 2019 Mar; 16(3):1406-1411. PubMed ID: 30608704
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Current Concepts in Drug-Induced Bile Salt Export Pump (BSEP) Interference.
    Kenna JG
    Curr Protoc Toxicol; 2014 Aug; 61():23.7.1-15. PubMed ID: 25104267
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The C-DILI™ Assay: An Integrated In Vitro Approach to Predict Cholestatic Hepatotoxicity.
    Jackson JP; Brouwer KR
    Methods Mol Biol; 2019; 1981():75-85. PubMed ID: 31016648
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Assessment of Bile Salt Export Pump (BSEP) Inhibition in Membrane Vesicles Using Radioactive and LC/MS-Based Detection Methods.
    Marroquin LD; Bonin PD; Keefer J; Schroeter T
    Curr Protoc Toxicol; 2017 Feb; 71():14.14.1-14.14.20. PubMed ID: 28146280
    [TBL] [Abstract][Full Text] [Related]  

  • 9. BSEP inhibition: in vitro screens to assess cholestatic potential of drugs.
    Kis E; Ioja E; Rajnai Z; Jani M; Méhn D; Herédi-Szabó K; Krajcsi P
    Toxicol In Vitro; 2012 Dec; 26(8):1294-9. PubMed ID: 22120137
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Warner DJ; Chen H; Cantin LD; Kenna JG; Stahl S; Walker CL; Noeske T
    Drug Metab Dispos; 2012 Dec; 40(12):2332-41. PubMed ID: 22961681
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Toward predicting drug-induced liver injury: parallel computational approaches to identify multidrug resistance protein 4 and bile salt export pump inhibitors.
    Welch MA; Köck K; Urban TJ; Brouwer KL; Swaan PW
    Drug Metab Dispos; 2015 May; 43(5):725-34. PubMed ID: 25735837
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Drug- and estrogen-induced cholestasis through inhibition of the hepatocellular bile salt export pump (Bsep) of rat liver.
    Stieger B; Fattinger K; Madon J; Kullak-Ublick GA; Meier PJ
    Gastroenterology; 2000 Feb; 118(2):422-30. PubMed ID: 10648470
    [TBL] [Abstract][Full Text] [Related]  

  • 13. In vitro model systems to investigate bile salt export pump (BSEP) activity and drug interactions: A review.
    Cheng Y; Woolf TF; Gan J; He K
    Chem Biol Interact; 2016 Aug; 255():23-30. PubMed ID: 26683212
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A Change in Bile Flow: Looking Beyond Transporter Inhibition in the Development of Drug-induced Cholestasis.
    Garzel B; Zhang L; Huang SM; Wang H
    Curr Drug Metab; 2019; 20(8):621-632. PubMed ID: 31288715
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Hepatocanalicular bile salt export pump deficiency in patients with progressive familial intrahepatic cholestasis.
    Jansen PL; Strautnieks SS; Jacquemin E; Hadchouel M; Sokal EM; Hooiveld GJ; Koning JH; De Jager-Krikken A; Kuipers F; Stellaard F; Bijleveld CM; Gouw A; Van Goor H; Thompson RJ; Müller M
    Gastroenterology; 1999 Dec; 117(6):1370-9. PubMed ID: 10579978
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Disruption of BSEP Function in HepaRG Cells Alters Bile Acid Disposition and Is a Susceptive Factor to Drug-Induced Cholestatic Injury.
    Qiu X; Zhang Y; Liu T; Shen H; Xiao Y; Bourner MJ; Pratt JR; Thompson DC; Marathe P; Humphreys WG; Lai Y
    Mol Pharm; 2016 Apr; 13(4):1206-16. PubMed ID: 26910619
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Expression of the bile salt export pump is maintained after chronic cholestasis in the rat.
    Lee JM; Trauner M; Soroka CJ; Stieger B; Meier PJ; Boyer JL
    Gastroenterology; 2000 Jan; 118(1):163-72. PubMed ID: 10611165
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Morgan RE; Trauner M; van Staden CJ; Lee PH; Ramachandran B; Eschenberg M; Afshari CA; Qualls CW; Lightfoot-Dunn R; Hamadeh HK
    Toxicol Sci; 2010 Dec; 118(2):485-500. PubMed ID: 20829430
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The bile salt export pump (BSEP) in health and disease.
    Kubitz R; Dröge C; Stindt J; Weissenberger K; Häussinger D
    Clin Res Hepatol Gastroenterol; 2012 Dec; 36(6):536-53. PubMed ID: 22795478
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Development of a mechanistic biokinetic model for hepatic bile acid handling to predict possible cholestatic effects of drugs.
    Notenboom S; Weigand KM; Proost JH; van Lipzig MMH; van de Steeg E; van den Broek PHH; Greupink R; Russel FGM; Groothuis GMM
    Eur J Pharm Sci; 2018 Mar; 115():175-184. PubMed ID: 29309877
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.