206 related articles for article (PubMed ID: 33503428)
1. Genome-wide CRISPR-Cas9 knockout library screening identified PTPMT1 in cardiolipin synthesis is crucial to survival in hypoxia in liver cancer.
Bao MH; Yang C; Tse AP; Wei L; Lee D; Zhang MS; Goh CC; Chiu DK; Yuen VW; Law CT; Chin WC; Chui NN; Wong BP; Chan CY; Ng IO; Chung CY; Wong CM; Wong CC
Cell Rep; 2021 Jan; 34(4):108676. PubMed ID: 33503428
[TBL] [Abstract][Full Text] [Related]
2. Hypoxia regulates the mitochondrial activity of hepatocellular carcinoma cells through HIF/HEY1/PINK1 pathway.
Kung-Chun Chiu D; Pui-Wah Tse A; Law CT; Ming-Jing Xu I; Lee D; Chen M; Kit-Ho Lai R; Wai-Hin Yuen V; Wing-Sum Cheu J; Wai-Hung Ho D; Wong CM; Zhang H; Oi-Lin Ng I; Chak-Lui Wong C
Cell Death Dis; 2019 Dec; 10(12):934. PubMed ID: 31819034
[TBL] [Abstract][Full Text] [Related]
3. Mitochondrial phosphatase PTPMT1 is essential for cardiolipin biosynthesis.
Zhang J; Guan Z; Murphy AN; Wiley SE; Perkins GA; Worby CA; Engel JL; Heacock P; Nguyen OK; Wang JH; Raetz CR; Dowhan W; Dixon JE
Cell Metab; 2011 Jun; 13(6):690-700. PubMed ID: 21641550
[TBL] [Abstract][Full Text] [Related]
4. CRISPR/Cas9-mediated knockout of NSD1 suppresses the hepatocellular carcinoma development via the NSD1/H3/Wnt10b signaling pathway.
Zhang S; Zhang F; Chen Q; Wan C; Xiong J; Xu J
J Exp Clin Cancer Res; 2019 Nov; 38(1):467. PubMed ID: 31727171
[TBL] [Abstract][Full Text] [Related]
5. Ptpmt1 induced by HIF-2α regulates the proliferation and glucose metabolism in erythroleukemia cells.
Xu QQ; Xiao FJ; Sun HY; Shi XF; Wang H; Yang YF; Li YX; Wang LS; Ge RL
Biochem Biophys Res Commun; 2016 Mar; 471(4):459-65. PubMed ID: 26898802
[TBL] [Abstract][Full Text] [Related]
6. Metformin suppresses hypoxia-induced stabilization of HIF-1α through reprogramming of oxygen metabolism in hepatocellular carcinoma.
Zhou X; Chen J; Yi G; Deng M; Liu H; Liang M; Shi B; Fu X; Chen Y; Chen L; He Z; Wang J; Liu J
Oncotarget; 2016 Jan; 7(1):873-84. PubMed ID: 26621849
[TBL] [Abstract][Full Text] [Related]
7. Modulation of hypoxia-signaling pathways by extracellular linc-RoR.
Takahashi K; Yan IK; Haga H; Patel T
J Cell Sci; 2014 Apr; 127(Pt 7):1585-94. PubMed ID: 24463816
[TBL] [Abstract][Full Text] [Related]
8. Genome-wide CRISPR knockout screens identify ADAMTSL3 and PTEN genes as suppressors of HCC proliferation and metastasis, respectively.
Zhou X; Li R; Jing R; Zuo B; Zheng Q
J Cancer Res Clin Oncol; 2020 Jun; 146(6):1509-1521. PubMed ID: 32266537
[TBL] [Abstract][Full Text] [Related]
9. PTPMT1 Is Required for Embryonic Cardiac Cardiolipin Biosynthesis to Regulate Mitochondrial Morphogenesis and Heart Development.
Chen Z; Zhu S; Wang H; Wang L; Zhang J; Gu Y; Tan C; Dhanani M; Wever E; Wang X; Xie B; Wang S; Huang L; van Kampen AHC; Liu J; Han Z; Patel HH; Vaz FM; Fang X; Chen J; Ouyang K
Circulation; 2021 Aug; 144(5):403-406. PubMed ID: 34339306
[No Abstract] [Full Text] [Related]
10. Downregulation of the mitochondrial phosphatase PTPMT1 is sufficient to promote cancer cell death.
Niemi NM; Lanning NJ; Westrate LM; MacKeigan JP
PLoS One; 2013; 8(1):e53803. PubMed ID: 23326511
[TBL] [Abstract][Full Text] [Related]
11. 2-Methoxyestradiol synergizes with sorafenib to suppress hepatocellular carcinoma by simultaneously dysregulating hypoxia-inducible factor-1 and -2.
Ma L; Li G; Zhu H; Dong X; Zhao D; Jiang X; Li J; Qiao H; Ni S; Sun X
Cancer Lett; 2014 Dec; 355(1):96-105. PubMed ID: 25218350
[TBL] [Abstract][Full Text] [Related]
12. Structural and functional analysis of PTPMT1, a phosphatase required for cardiolipin synthesis.
Xiao J; Engel JL; Zhang J; Chen MJ; Manning G; Dixon JE
Proc Natl Acad Sci U S A; 2011 Jul; 108(29):11860-5. PubMed ID: 21730175
[TBL] [Abstract][Full Text] [Related]
13. CRISPR/Cas9-based Pten knock-out and Sleeping Beauty Transposon-mediated Nras knock-in induces hepatocellular carcinoma and hepatic lipid accumulation in mice.
Gao M; Liu D
Cancer Biol Ther; 2017 Jul; 18(7):505-512. PubMed ID: 28513320
[TBL] [Abstract][Full Text] [Related]
14. Genome-Wide CRISPR Screen Identifies Regulators of Mitogen-Activated Protein Kinase as Suppressors of Liver Tumors in Mice.
Song CQ; Li Y; Mou H; Moore J; Park A; Pomyen Y; Hough S; Kennedy Z; Fischer A; Yin H; Anderson DG; Conte D; Zender L; Wang XW; Thorgeirsson S; Weng Z; Xue W
Gastroenterology; 2017 Apr; 152(5):1161-1173.e1. PubMed ID: 27956228
[TBL] [Abstract][Full Text] [Related]
15. Simultaneous knockdown of YAP and TAZ increases apoptosis of hepatocellular carcinoma cells under hypoxic condition.
Yan B; Li T; Shen L; Zhou Z; Liu X; Wang X; Sun X
Biochem Biophys Res Commun; 2019 Jul; 515(2):275-281. PubMed ID: 31146919
[TBL] [Abstract][Full Text] [Related]
16. NDUFA4L2 Fine-tunes Oxidative Stress in Hepatocellular Carcinoma.
Lai RK; Xu IM; Chiu DK; Tse AP; Wei LL; Law CT; Lee D; Wong CM; Wong MP; Ng IO; Wong CC
Clin Cancer Res; 2016 Jun; 22(12):3105-17. PubMed ID: 26819450
[TBL] [Abstract][Full Text] [Related]
17. Loss-of-Function Genetic Screening Identifies Aldolase A as an Essential Driver for Liver Cancer Cell Growth Under Hypoxia.
Niu Y; Lin Z; Wan A; Sun L; Yan S; Liang H; Zhan S; Chen D; Bu X; Liu P; Chen C; He W; Lu X; Wan G
Hepatology; 2021 Sep; 74(3):1461-1479. PubMed ID: 33813748
[TBL] [Abstract][Full Text] [Related]
18. A critical role of mitochondrial phosphatase Ptpmt1 in embryogenesis reveals a mitochondrial metabolic stress-induced differentiation checkpoint in embryonic stem cells.
Shen J; Liu X; Yu WM; Liu J; Nibbelink MG; Guo C; Finkel T; Qu CK
Mol Cell Biol; 2011 Dec; 31(24):4902-16. PubMed ID: 21986498
[TBL] [Abstract][Full Text] [Related]
19. Mitochondrial UQCC3 Modulates Hypoxia Adaptation by Orchestrating OXPHOS and Glycolysis in Hepatocellular Carcinoma.
Yang Y; Zhang G; Guo F; Li Q; Luo H; Shu Y; Shen Y; Gan J; Xu L; Yang H
Cell Rep; 2020 Nov; 33(5):108340. PubMed ID: 33147459
[TBL] [Abstract][Full Text] [Related]
20. Yes-associated protein (YAP) binds to HIF-1α and sustains HIF-1α protein stability to promote hepatocellular carcinoma cell glycolysis under hypoxic stress.
Zhang X; Li Y; Ma Y; Yang L; Wang T; Meng X; Zong Z; Sun X; Hua X; Li H
J Exp Clin Cancer Res; 2018 Sep; 37(1):216. PubMed ID: 30180863
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
