BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

245 related articles for article (PubMed ID: 33510150)

  • 1. Hyperpolyploidization of hepatocyte initiates preneoplastic lesion formation in the liver.
    Lin H; Huang YS; Fustin JM; Doi M; Chen H; Lai HH; Lin SH; Lee YL; King PC; Hou HS; Chen HW; Young PY; Chao HW
    Nat Commun; 2021 Jan; 12(1):645. PubMed ID: 33510150
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Persistent hepatocyte apoptosis promotes tumorigenesis from diethylnitrosamine-transformed hepatocytes through increased oxidative stress, independent of compensatory liver regeneration.
    Nozaki Y; Hikita H; Tanaka S; Fukumoto K; Urabe M; Sato K; Myojin Y; Doi A; Murai K; Sakane S; Saito Y; Kodama T; Sakamori R; Tatsumi T; Takehara T
    Sci Rep; 2021 Feb; 11(1):3363. PubMed ID: 33564095
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Mice With Increased Numbers of Polyploid Hepatocytes Maintain Regenerative Capacity But Develop Fewer Hepatocellular Carcinomas Following Chronic Liver Injury.
    Lin YH; Zhang S; Zhu M; Lu T; Chen K; Wen Z; Wang S; Xiao G; Luo D; Jia Y; Li L; MacConmara M; Hoshida Y; Singal AG; Yopp A; Wang T; Zhu H
    Gastroenterology; 2020 May; 158(6):1698-1712.e14. PubMed ID: 31972235
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Caspase-3 suppresses diethylnitrosamine-induced hepatocyte death, compensatory proliferation and hepatocarcinogenesis through inhibiting p38 activation.
    Shang N; Bank T; Ding X; Breslin P; Li J; Shi B; Qiu W
    Cell Death Dis; 2018 May; 9(5):558. PubMed ID: 29752472
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Bile acids promote diethylnitrosamine-induced hepatocellular carcinoma via increased inflammatory signaling.
    Sun L; Beggs K; Borude P; Edwards G; Bhushan B; Walesky C; Roy N; Manley MW; Gunewardena S; O'Neil M; Li H; Apte U
    Am J Physiol Gastrointest Liver Physiol; 2016 Jul; 311(1):G91-G104. PubMed ID: 27151938
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Quantitative analysis of hepatic hypoxia-inducible factor-1alpha and its abnormal gene expression during the formation of hepatocellular carcinoma.
    Yao DF; Jiang H; Yao M; Li YM; Gu WJ; Shen YC; Qiu LW; Wu W; Wu XH; Sai WL
    Hepatobiliary Pancreat Dis Int; 2009 Aug; 8(4):407-13. PubMed ID: 19666411
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Expression Characteristics of Genes Hypermethylated and Downregulated in Rat Liver Specific to Nongenotoxic Hepatocarcinogens.
    Ito Y; Nakajima K; Masubuchi Y; Kikuchi S; Saito F; Akahori Y; Jin M; Yoshida T; Shibutani M
    Toxicol Sci; 2019 May; 169(1):122-136. PubMed ID: 30690589
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Knockdown of Anillin Actin Binding Protein Blocks Cytokinesis in Hepatocytes and Reduces Liver Tumor Development in Mice Without Affecting Regeneration.
    Zhang S; Nguyen LH; Zhou K; Tu HC; Sehgal A; Nassour I; Li L; Gopal P; Goodman J; Singal AG; Yopp A; Zhang Y; Siegwart DJ; Zhu H
    Gastroenterology; 2018 Apr; 154(5):1421-1434. PubMed ID: 29274368
    [TBL] [Abstract][Full Text] [Related]  

  • 9. EGFR has a tumour-promoting role in liver macrophages during hepatocellular carcinoma formation.
    Lanaya H; Natarajan A; Komposch K; Li L; Amberg N; Chen L; Wculek SK; Hammer M; Zenz R; Peck-Radosavljevic M; Sieghart W; Trauner M; Wang H; Sibilia M
    Nat Cell Biol; 2014 Oct; 16(10):972-7. PubMed ID: 25173978
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Metabolic reprogramming identifies the most aggressive lesions at early phases of hepatic carcinogenesis.
    Kowalik MA; Guzzo G; Morandi A; Perra A; Menegon S; Masgras I; Trevisan E; Angioni MM; Fornari F; Quagliata L; Ledda-Columbano GM; Gramantieri L; Terracciano L; Giordano S; Chiarugi P; Rasola A; Columbano A
    Oncotarget; 2016 May; 7(22):32375-93. PubMed ID: 27070090
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Interferon-microRNA signalling drives liver precancerous lesion formation and hepatocarcinogenesis.
    Yang Y; Lin X; Lu X; Luo G; Zeng T; Tang J; Jiang F; Li L; Cui X; Huang W; Hou G; Chen X; Ouyang Q; Tang S; Sun H; Chen L; Gonzalez FJ; Wu M; Cong W; Chen L; Wang H
    Gut; 2016 Jul; 65(7):1186-201. PubMed ID: 26860770
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Continuous cell injury promotes hepatic tumorigenesis in cdc42-deficient mouse liver.
    van Hengel J; D'Hooge P; Hooghe B; Wu X; Libbrecht L; De Vos R; Quondamatteo F; Klempt M; Brakebusch C; van Roy F
    Gastroenterology; 2008 Mar; 134(3):781-92. PubMed ID: 18325391
    [TBL] [Abstract][Full Text] [Related]  

  • 13. IL-17 signaling in steatotic hepatocytes and macrophages promotes hepatocellular carcinoma in alcohol-related liver disease.
    Ma HY; Yamamoto G; Xu J; Liu X; Karin D; Kim JY; Alexandrov LB; Koyama Y; Nishio T; Benner C; Heinz S; Rosenthal SB; Liang S; Sun M; Karin G; Zhao P; Brodt P; Mckillop IH; Quehenberger O; Dennis E; Saltiel A; Tsukamoto H; Gao B; Karin M; Brenner DA; Kisseleva T
    J Hepatol; 2020 May; 72(5):946-959. PubMed ID: 31899206
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Astrocyte elevated gene-1 promotes hepatocarcinogenesis: novel insights from a mouse model.
    Srivastava J; Siddiq A; Emdad L; Santhekadur PK; Chen D; Gredler R; Shen XN; Robertson CL; Dumur CI; Hylemon PB; Mukhopadhyay ND; Bhere D; Shah K; Ahmad R; Giashuddin S; Stafflinger J; Subler MA; Windle JJ; Fisher PB; Sarkar D
    Hepatology; 2012 Nov; 56(5):1782-91. PubMed ID: 22689379
    [TBL] [Abstract][Full Text] [Related]  

  • 15. STARD1 promotes NASH-driven HCC by sustaining the generation of bile acids through the alternative mitochondrial pathway.
    Conde de la Rosa L; Garcia-Ruiz C; Vallejo C; Baulies A; Nuñez S; Monte MJ; Marin JJG; Baila-Rueda L; Cenarro A; Civeira F; Fuster J; Garcia-Valdecasas JC; Ferrer J; Karin M; Ribas V; Fernandez-Checa JC
    J Hepatol; 2021 Jun; 74(6):1429-1441. PubMed ID: 33515644
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Targeted deletion of ER chaperone GRP94 in the liver results in injury, repopulation of GRP94-positive hepatocytes, and spontaneous hepatocellular carcinoma development in aged mice.
    Chen WT; Ha D; Kanel G; Lee AS
    Neoplasia; 2014 Aug; 16(8):617-26. PubMed ID: 25220589
    [TBL] [Abstract][Full Text] [Related]  

  • 17. WWOX controls hepatic HIF1α to suppress hepatocyte proliferation and neoplasia.
    Abu-Remaileh M; Khalaileh A; Pikarsky E; Aqeilan RI
    Cell Death Dis; 2018 May; 9(5):511. PubMed ID: 29724996
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Role of insulin receptor substrates in the progression of hepatocellular carcinoma.
    Sakurai Y; Kubota N; Takamoto I; Obata A; Iwamoto M; Hayashi T; Aihara M; Kubota T; Nishihara H; Kadowaki T
    Sci Rep; 2017 Jul; 7(1):5387. PubMed ID: 28710407
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Liver polyploidy: Dr Jekyll or Mr Hide?
    Gentric G; Desdouets C
    Oncotarget; 2015 Apr; 6(11):8430-1. PubMed ID: 25940698
    [No Abstract]   [Full Text] [Related]  

  • 20. Downregulation of low-density lipoprotein receptor class A domain-containing protein 4 (Ldlrad4) in the liver of rats treated with nongenotoxic hepatocarcinogen to induce transforming growth factor β signaling promoting cell proliferation and suppressing apoptosis in early hepatocarcinogenesis.
    Ito Y; Nakajima K; Masubuchi Y; Kikuchi S; Okano H; Saito F; Akahori Y; Jin M; Yoshida T; Shibutani M
    J Appl Toxicol; 2020 Nov; 40(11):1467-1479. PubMed ID: 32596862
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.