BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

226 related articles for article (PubMed ID: 33514790)

  • 1. LC-MS based case-by-case analysis of the impact of acidic and basic charge variants of bevacizumab on stability and biological activity.
    Singh SK; Kumar D; Malani H; Rathore AS
    Sci Rep; 2021 Jan; 11(1):2487. PubMed ID: 33514790
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Similarity demonstrated between isolated charge variants of MB02, a biosimilar of bevacizumab, and Avastin® following extended physicochemical and functional characterization.
    Ruppen I; Beydon ME; Solís C; Sacristán D; Vandenheede I; Ortiz A; Sandra K; Adhikary L
    Biologicals; 2022 Jun; 77():1-15. PubMed ID: 35667958
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Rapid characterization of structural and functional similarity for a candidate bevacizumab (Avastin) biosimilar using a multipronged mass-spectrometry-based approach.
    Brown KA; Rajendran S; Dowd J; Wilson DJ
    Drug Test Anal; 2019 Aug; 11(8):1207-1217. PubMed ID: 31041833
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Biophysical study of bevacizumab structure and bioactivity under thermal and pH-stresses.
    Sousa F; Sarmento B; Neves-Petersen MT
    Eur J Pharm Sci; 2017 Jul; 105():127-136. PubMed ID: 28502677
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Similarity demonstrated between isolated charge variants of MB02, a biosimilar of bevacizumab, and Avastin® following extended physicochemical and functional characterization.
    Ruppen I; Beydon ME; Solís C; Sacristán D; Vandenheede I; Ortiz A; Sandra K; Adhikary L
    Biologicals; 2021 Sep; 73():41-56. PubMed ID: 34593306
    [TBL] [Abstract][Full Text] [Related]  

  • 6. In-depth size and charge variants characterization of monoclonal antibody with native mass spectrometry.
    Dai J; Ji C
    Anal Chim Acta; 2023 Jul; 1265():341360. PubMed ID: 37230578
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Isolation and characterization of charge variants of infliximab biosimilar HS626.
    Yuan JJ; Gao D; Hu F; Shi Y; Wu ZH; Hu CQ; Huang XD; Fang WJ; Zhang HT; Wang HB
    J Chromatogr B Analyt Technol Biomed Life Sci; 2021 Jan; 1162():122485. PubMed ID: 33360415
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Structural and Functional Analysis of CEX Fractions Collected from a Novel Avastin
    Gurel B; Berksoz M; Capkin E; Parlar A; Pala MC; Ozkan A; Capan Y; Daglikoca DE; Yuce M
    Pharmaceutics; 2022 Jul; 14(8):. PubMed ID: 36015197
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Simultaneous Monitoring of Monoclonal Antibody Variants by Strong Cation-Exchange Chromatography Hyphenated to Mass Spectrometry to Assess Quality Attributes of Rituximab-Based Biotherapeutics.
    Di Marco F; Berger T; Esser-Skala W; Rapp E; Regl C; Huber CG
    Int J Mol Sci; 2021 Aug; 22(16):. PubMed ID: 34445776
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Charge Variants of an Avastin Biosimilar Isolation, Characterization, In Vitro Properties and Pharmacokinetics in Rat.
    Zhao YY; Wang N; Liu WH; Tao WJ; Liu LL; Shen ZD
    PLoS One; 2016; 11(3):e0151874. PubMed ID: 26987122
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Multiattribute Monitoring of Antibody Charge Variants by Cation-Exchange Chromatography Coupled to Native Mass Spectrometry.
    Haberger M; Heidenreich AK; Hook M; Fichtl J; Lang R; Cymer F; Adibzadeh M; Kuhne F; Wegele H; Reusch D; Bonnington L; Bulau P
    J Am Soc Mass Spectrom; 2021 Aug; 32(8):2062-2071. PubMed ID: 33687195
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Nonclinical assessments of the potential biosimilar PF-06439535 and bevacizumab.
    Peraza MA; Rule KE; Shiue MHI; Finch GL; Thibault S; Brown PR; Clarke DW; Leach MW
    Regul Toxicol Pharmacol; 2018 Jun; 95():236-243. PubMed ID: 29574193
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A Charge Variant of Bevacizumab Offers Enhanced FcRn-Dependent Pharmacokinetic Half-Life and Efficacy.
    Singh SK; Kumar D; Nagpal S; Dubey SK; Rathore AS
    Pharm Res; 2022 May; 39(5):851-865. PubMed ID: 35355206
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Assessment of change in the basic variants composition of trastuzumab during dilution in saline for administration.
    Gupta S; Schöneich C; Rathore AS
    Eur J Pharm Biopharm; 2024 Jun; 199():114295. PubMed ID: 38636881
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Characterization of therapeutic proteins by cation exchange chromatography-mass spectrometry and top-down analysis.
    Shi RL; Xiao G; Dillon TM; Ricci MS; Bondarenko PV
    MAbs; 2020; 12(1):1739825. PubMed ID: 32292112
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Part 2: Physicochemical characterization of bevacizumab in 2 mg/mL antibody solutions as used in human i.v. administration: Comparison of originator with a biosimilar candidate.
    Arvinte T; Palais C; Poirier E; Cudd A; Rajendran S; Brokx S; Dowd J
    J Pharm Biomed Anal; 2019 Nov; 176():112802. PubMed ID: 31446298
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Characterization of Recombinant Monoclonal Antibody Charge Variants Using OFFGEL Fractionation, Weak Anion Exchange Chromatography, and Mass Spectrometry.
    Neill A; Nowak C; Patel R; Ponniah G; Gonzalez N; Miano D; Liu H
    Anal Chem; 2015 Jun; 87(12):6204-11. PubMed ID: 25977987
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Insights into the generation of monoclonal antibody acidic charge variants during Chinese hamster ovary cell cultures.
    Tang H; Miao S; Zhang X; Fan L; Liu X; Tan WS; Zhao L
    Appl Microbiol Biotechnol; 2018 Feb; 102(3):1203-1214. PubMed ID: 29238873
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Assessment of structural and functional similarity of biosimilar products: Bevacizumab as a case study.
    Bhattacharya S; Rathore AS
    J Chromatogr B Analyt Technol Biomed Life Sci; 2023 Sep; 1229():123896. PubMed ID: 37776677
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Investigation of the correlation between charge and glycosylation of IgG1 variants by liquid chromatography-mass spectrometry.
    Yang JM; Ai J; Bao Y; Yuan Z; Qin Y; Xie YW; Tao D; Fu D; Peng Y
    Anal Biochem; 2014 Mar; 448():82-91. PubMed ID: 24287081
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.