167 related articles for article (PubMed ID: 33515864)
1. Discovery and development of novel pyrimidine and pyrazolo/thieno-fused pyrimidine derivatives as potent and orally active inducible nitric oxide synthase dimerization inhibitor with efficacy for arthritis.
Chen LZ; Shu HY; Wu J; Yu YL; Ma D; Huang X; Liu MM; Liu XH; Shi JB
Eur J Med Chem; 2021 Mar; 213():113174. PubMed ID: 33515864
[TBL] [Abstract][Full Text] [Related]
2. Novel Pyrazolo[4,3- d]pyrimidine as Potent and Orally Active Inducible Nitric Oxide Synthase (iNOS) Dimerization Inhibitor with Efficacy in Rheumatoid Arthritis Mouse Model.
Shi JB; Chen LZ; Wang BS; Huang X; Jiao MM; Liu MM; Tang WJ; Liu XH
J Med Chem; 2019 Apr; 62(8):4013-4031. PubMed ID: 30925056
[TBL] [Abstract][Full Text] [Related]
3. Design and synthesis of novel pyrazolo[4,3-
Wang BS; Huang X; Chen LZ; Liu MM; Shi JB
J Enzyme Inhib Med Chem; 2019 Dec; 34(1):1121-1130. PubMed ID: 31117832
[TBL] [Abstract][Full Text] [Related]
4. Development of a novel nitric oxide (NO) production inhibitor with potential therapeutic effect on chronic inflammation.
Yang Y; Wei Z; Teichmann AT; Wieland FH; Wang A; Lei X; Zhu Y; Yin J; Fan T; Zhou L; Wang C; Chen L
Eur J Med Chem; 2020 May; 193():112216. PubMed ID: 32208222
[TBL] [Abstract][Full Text] [Related]
5. Mechanism of inducible nitric-oxide synthase dimerization inhibition by novel pyrimidine imidazoles.
Nagpal L; Haque MM; Saha A; Mukherjee N; Ghosh A; Ranu BC; Stuehr DJ; Panda K
J Biol Chem; 2013 Jul; 288(27):19685-97. PubMed ID: 23696643
[TBL] [Abstract][Full Text] [Related]
6. Novel paeonol derivatives: Design, synthesis and anti-inflammatory activity in vitro and in vivo.
Hu YS; Han X; Yu PJ; Jiao MM; Liu XH; Shi JB
Bioorg Chem; 2020 May; 98():103735. PubMed ID: 32171986
[TBL] [Abstract][Full Text] [Related]
7. Structural exploration, synthesis and pharmacological evaluation of novel 5-benzylidenethiazolidine-2,4-dione derivatives as iNOS inhibitors against inflammatory diseases.
Ma L; Pei H; Lei L; He L; Chen J; Liang X; Peng A; Ye H; Xiang M; Chen L
Eur J Med Chem; 2015 Mar; 92():178-90. PubMed ID: 25555141
[TBL] [Abstract][Full Text] [Related]
8. Synthesis, evaluation and docking of novel pyrazolo pyrimidines as potent p38α MAP kinase inhibitors with improved anti-inflammatory, ulcerogenic and TNF-α inhibitory properties.
Somakala K; Tariq S; Amir M
Bioorg Chem; 2019 Jun; 87():550-559. PubMed ID: 30928877
[TBL] [Abstract][Full Text] [Related]
9. Pyrazoloheteroaryls: novel p38alpha MAP kinase inhibiting scaffolds with oral activity.
Revesz L; Blum E; Di Padova FE; Buhl T; Feifel R; Gram H; Hiestand P; Manning U; Neumann U; Rucklin G
Bioorg Med Chem Lett; 2006 Jan; 16(2):262-6. PubMed ID: 16249085
[TBL] [Abstract][Full Text] [Related]
10. Design, Synthesis, and Biological Activity of Tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidine Derivatives as Anti-Inflammatory Agents.
Zhang Y; Luo L; Han C; Lv H; Chen D; Shen G; Wu K; Pan S; Ye F
Molecules; 2017 Nov; 22(11):. PubMed ID: 29137170
[TBL] [Abstract][Full Text] [Related]
11. Discovery of inducible nitric oxide synthase (iNOS) inhibitor development candidate KD7332, part 1: Identification of a novel, potent, and selective series of quinolinone iNOS dimerization inhibitors that are orally active in rodent pain models.
Bonnefous C; Payne JE; Roppe J; Zhuang H; Chen X; Symons KT; Nguyen PM; Sablad M; Rozenkrants N; Zhang Y; Wang L; Severance D; Walsh JP; Yazdani N; Shiau AK; Noble SA; Rix P; Rao TS; Hassig CA; Smith ND
J Med Chem; 2009 May; 52(9):3047-62. PubMed ID: 19374401
[TBL] [Abstract][Full Text] [Related]
12. Novel Pyrazolo[3,4-d]pyrimidines as Potential Cytotoxic Agents: Design, Synthesis, Molecular Docking and CDK2 Inhibition.
Maher M; Kassab AE; Zaher AF; Mahmoud Z
Anticancer Agents Med Chem; 2019; 19(11):1368-1381. PubMed ID: 31038080
[TBL] [Abstract][Full Text] [Related]
13. Synthesis, EGFR Inhibition and Anti-cancer Activity of New 3,6-dimethyl-1-phenyl-4-(substituted-methoxy)pyrazolo[3,4-d] pyrimidine Derivatives.
Bakr RB; Mehany ABM; Abdellatif KRA
Anticancer Agents Med Chem; 2017; 17(10):1389-1400. PubMed ID: 28270084
[TBL] [Abstract][Full Text] [Related]
14. New arylpyrazoline-coumarins: Synthesis and anti-inflammatory activity.
Chen LZ; Sun WW; Bo L; Wang JQ; Xiu C; Tang WJ; Shi JB; Zhou HP; Liu XH
Eur J Med Chem; 2017 Sep; 138():170-181. PubMed ID: 28667873
[TBL] [Abstract][Full Text] [Related]
15. Synthesis and biological activity of new phthalimides as potential anti-inflammatory agents.
Bach DH; Liu JY; Kim WK; Hong JY; Park SH; Kim D; Qin SN; Luu TT; Park HJ; Xu YN; Lee SK
Bioorg Med Chem; 2017 Jul; 25(13):3396-3405. PubMed ID: 28478865
[TBL] [Abstract][Full Text] [Related]
16. Withapubesides A-D: natural inducible nitric oxide synthase (iNOS) inhibitors from Physalis pubescens.
Xia GY; Yao T; Zhang BY; Li Y; Kang N; Cao SJ; Ding LQ; Chen LX; Qiu F
Org Biomol Chem; 2017 Dec; 15(47):10016-10023. PubMed ID: 29164214
[TBL] [Abstract][Full Text] [Related]
17. Anti-inflammatory efficacy and relevant SAR investigations of novel chiral pyrazolo isoquinoline derivatives: Design, synthesis, in-vitro, in-vivo, and computational studies targeting iNOS.
Akhtar M; Niu J; Zhu Y; Luo Z; Tian T; Dong Y; Wang Y; Fareed MS; Lin L
Eur J Med Chem; 2023 Aug; 256():115412. PubMed ID: 37146344
[TBL] [Abstract][Full Text] [Related]
18. Novel unsaturated glycyrrhetic acids derivatives: Design, synthesis and anti-inflammatory activity.
Li B; Cai S; Yang YA; Chen SC; Chen R; Shi JB; Liu XH; Tang WJ
Eur J Med Chem; 2017 Oct; 139():337-348. PubMed ID: 28803048
[TBL] [Abstract][Full Text] [Related]
19. Synthesis, docking and evaluation of in vitro anti-inflammatory activity of novel morpholine capped β-lactam derivatives.
Heiran R; Sepehri S; Jarrahpour A; Digiorgio C; Douafer H; Brunel JM; Gholami A; Riazimontazer E; Turos E
Bioorg Chem; 2020 Sep; 102():104091. PubMed ID: 32717692
[TBL] [Abstract][Full Text] [Related]
20. Novel pyrazolopyrimidine derivatives targeting COXs and iNOS enzymes; design, synthesis and biological evaluation as potential anti-inflammatory agents.
Abdelazeem AH; Abdelatef SA; El-Saadi MT; Omar HA; Khan SI; McCurdy CR; El-Moghazy SM
Eur J Pharm Sci; 2014 Oct; 62():197-211. PubMed ID: 24907682
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
